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Journal of Clinical Medicine, Volume 13, Issue 20

October-2 2024 - 266 articles

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Cover Story: Hypertension is emerging as a modifiable risk factor for major neurocognitive disorders, contributing to neurodegenerative processes through vascular damage, inflammation, and blood–brain barrier disruption. However, the role of antihypertensive treatments in preventing or treating cognitive decline remains unclear, with mixed evidence varying by antihypertensive class and the type of neurocognitive disorder, including delirium, Alzheimer’s disease, vascular dementia, Lewy body dementia, and frontotemporal dementia. The complex, bidirectional relationship between hypertension and these disorders—along with variations in hypertension definitions, diagnostic criteria, and confounding factors like medication adherence—underscores the need for long-term studies to clarify the potential therapeutic benefits of antihypertensive treatments. View this paper

Articles (266)

  • Article
  • Open Access
1,460 Views
22 Pages

Clinical and Electrocardiographic Predictors of Cardiac Resynchronization Therapy Response That Correlate with the 6 min Walking Test

  • Andrei Mihnea Rosu,
  • Theodor Georgian Badea,
  • Florentina Luminita Tomescu,
  • Andreea Liana Rosu,
  • Emanuel Stefan Radu,
  • Oana Andreea Popa,
  • Liliana Catalina Andrei and
  • Crina Julieta Sinescu

21 October 2024

Background: Cardiac resynchronization therapy is an essential treatment for heart failure patients. Candidates typically have cardiomyopathy accompanied by delayed electrical activation in the left ventricular lateral wall, causing uncoordinated cont...

  • Systematic Review
  • Open Access
1 Citations
3,248 Views
24 Pages

Allograft Prosthetic Composite (APC) for Proximal Humeral Bone Deficiency in Revision Reverse Shoulder Arthroplasty: A Technical Note and Systematic Review

  • Hean Wu Kang,
  • Christopher Child,
  • Kristine Italia,
  • Mirek Karel,
  • Luke Gilliland,
  • Helen Ingoe,
  • Jashint Maharaj,
  • Sarah Whitehouse,
  • Kenneth Cutbush and
  • Ashish Gupta

21 October 2024

Background: Proximal humeral bone deficiency in revision shoulder arthroplasty is an emerging and challenging problem as the use of reverse shoulder arthroplasty (RSA) increases. This paper presents a technical note discussing our detailed preoperati...

  • Article
  • Open Access
1,254 Views
9 Pages

Vertebral Body Morphology in Neuromuscular Scoliosis with Spastic Quadriplegic Cerebral Palsy

  • Göker Utku Değer,
  • Heon Jung Park,
  • Kyeong-Hyeon Park,
  • Hoon Park,
  • Mohammed Salman Alhassan,
  • Hyun Woo Kim and
  • Kun-Bo Park

21 October 2024

Background/Objectives: The distorted vertebral body has been studied in scoliosis; however, there is little knowledge about the difference between neuromuscular and idiopathic scoliosis. This study aimed to investigate the vertebral body morphology i...

  • Article
  • Open Access
1 Citations
1,588 Views
14 Pages

Diagnostic Utility of the “Air Sign” as a Radiological Indicator for Mandibular Body and Angle Fractures

  • Weronika Michalik,
  • Joanna Kuczera,
  • Jakub Bargiel,
  • Krzysztof Gąsiorowski,
  • Tomasz Marecik,
  • Paweł Szczurowski,
  • Grażyna Wyszyńska-Pawelec and
  • Michał Gontarz

21 October 2024

Background: To plan optimal treatment, obtain satisfactory outcomes, and avoid undesirable clinical errors, surgeons need to have efficient tools for providing a complete and prompt diagnosis. The aim of this study was to establish the sensitivity, s...

  • Article
  • Open Access
4 Citations
2,142 Views
13 Pages

Dysmenorrhea in Polish Adolescent Girls: Impact on Physical, Mental, and Social Well-Being—Results from POLKA 18 Study

  • Michalina Drejza,
  • Katarzyna Rylewicz,
  • Ewa Majcherek,
  • Joanna Barwińska,
  • Grzegorz Łopiński,
  • Małgorzata Mizgier,
  • Katarzyna Plagens-Rotman,
  • Magdalena Pisarska-Krawczyk,
  • Grażyna Jarząbek-Bielecka and
  • Witold Kędzia

21 October 2024

Background: Dysmenorrhea, characterised by painful menstrual cramps, is a pressing issue among adolescent girls globally. It significantly impacts their quality of life and has been associated with increased mental health issues and engagement in ris...

  • Article
  • Open Access
2,085 Views
13 Pages

Evaluation and Treatment of Congenital Syphilis: A National Survey of US Pediatric Specialists

  • David B. Banks,
  • John M. Flores,
  • Jose Luis Paredes and
  • Simon L. Parzen-Johnson

21 October 2024

Background/Objectives: As congenital syphilis incidence continues to increase yearly in the United States (US), recommendations from government and professional organizations aim to inform effective clinical practice, although it is unclear how close...

  • Article
  • Open Access
5 Citations
3,916 Views
13 Pages

Enhanced Recovery After Surgery Protocols in One- or Two-Level Posterior Lumbar Fusion: Improving Postoperative Outcomes

  • Ji Uk Choi,
  • Tae-Hong Kee,
  • Dong-Ho Lee,
  • Chang Ju Hwang,
  • Sehan Park and
  • Jae Hwan Cho

21 October 2024

Background/Objectives: Enhanced recovery after surgery (ERAS) protocols optimize perioperative care and improve recovery. This study evaluated the effectiveness of ERAS in one- or two-level posterior lumbar fusion surgeries, focusing on perioperative...

  • Article
  • Open Access
2,296 Views
9 Pages

Self-Cross-Linked Hyaluronic Acid Gel for Adhesion Prophylaxis in Laparoscopic Deep Endometriosis Removal: Safety Report of a Prospective Pilot Study

  • Maya Sophie de Wilde,
  • Rajesh Devassy,
  • Harald Krentel,
  • Rudy Leon De Wilde and
  • Luz Angela Torres-de la Roche

21 October 2024

Background/Objectives: Surgical removal of deep endometriosis lesions is an established method of reducing patient symptoms, but it often results in iatrogenic adhesions that lead to further problems. This pilot study presents the safety evaluation o...

  • Systematic Review
  • Open Access
6 Citations
4,839 Views
20 Pages

Approaches to Deprescribing Proton Pump Inhibitors in Clinical Practice: A Systematic Review

  • Andrea Rossi,
  • Lara Perrella,
  • Stefano Scotti,
  • Elena Olmastroni,
  • Federica Galimberti,
  • Ilaria Ardoino,
  • Valentina Orlando,
  • Enrica Menditto,
  • Carlotta Franchi and
  • Manuela Casula

21 October 2024

Background: Proton pump inhibitors (PPIs) are some of the most frequently prescribed medications, but they are often used inappropriately, either being prescribed without a clear indication or continued for longer than necessary. In such cases, depre...

  • Article
  • Open Access
1 Citations
2,825 Views
14 Pages

Exploring Patient Empowerment in Major Depressive Disorder: Correlations of Trust, Active Role in Shared Decision-Making, and Symptomatology in a Sample of Italian Patients

  • Alessandro Rodolico,
  • Pierfelice Cutrufelli,
  • Giuliana Maccarone,
  • Gabriele Avincola,
  • Carmen Concerto,
  • Alfio Luca Cunsolo,
  • Antonio Di Francesco,
  • Rosaria Furnari,
  • Ludovico Mineo and
  • Federico Salerno
  • + 4 authors

21 October 2024

Background/Objectives: Empowerment in medicine and psychiatry involves patients gaining control over health-related decisions, improving treatment adherence, outcomes, and satisfaction. This concept is especially significant in psychiatric care due t...

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