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State-of-the-Art Developments in Percutaneous Coronary Intervention (PCI)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (20 July 2024) | Viewed by 1864

Special Issue Editor


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Guest Editor
Cardiology Department, Saitama Sekishinkai Hospital, 2-37-20 Irumagawa, Sayama 350-1305, Saitama, Japan
Interests: chronic total occlusion; percutaneous coronary intervention; PCI; interventional cardiology; coronary angiography; myocardial infarction; coronary CTOPCI

Special Issue Information

Dear Colleagues,

Though it has been over 40 years since the inception of percutaneous coronary intervention (PCI), PCI is not yet on a par with surgical revascularization (CABG) for occlusive coronary stenoses. While the adoption of Drug Eluting Stent (DES), high-speed atherectomy, dual-antiplatelet agents, intravascular imaging, and the therapeutic algorithm has contributed enormously to maximizing PCI procedural success, coronary chronic total occlusion (CTO) PCI remains the last frontier of interventional cardiology in terms of procedural success in comparison with non-CTO PCI. Since every coronary artery disease (CAD) is different, given lesion complexities, patient co-morbidities, and financial equities available in the healthcare system, much more than specialist expertise is needed to successfully treat the condition. While PCI has been proven to improve angina symptoms (an indication justifying the procedure), novel therapies have been developed and implemented with potentially durable, better clinical outcomes.

In this Special Issue, we welcome authors to submit papers on the clinical advancements of complex PCI or CTO PCI, thereby improving current indication, technicality, and device application.

Dr. Masahisa Yamane
Guest Editor

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Keywords

  • coronary artery disease
  • percutaneous coronary intervention
  • chronic total occlusion
  • cto-pci
  • drug eluting stent
  • drug coating balloon
  • intravascular lithotripsy
  • intravascular imaging
  • coronary computed tomography angiography
  • complex high-risk coronary intervention

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Published Papers (2 papers)

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Review

16 pages, 1091 KiB  
Review
Role of Mechanical Circulatory Support in Complex High-Risk and Indicated Percutaneous Coronary Intervention: Current Indications, Device Options, and Potential Complications
by Francesca Maria Di Muro, Michele Bellino, Luca Esposito, Tiziana Attisano, Francesco Meucci, Alessio Mattesini, Gennaro Galasso, Carmine Vecchione and Carlo Di Mario
J. Clin. Med. 2024, 13(16), 4931; https://doi.org/10.3390/jcm13164931 - 21 Aug 2024
Viewed by 516
Abstract
Improved expertise and technological advancements have enabled the safe and effective performance of complex and high-risk-indicated percutaneous coronary intervention (CHIP) in patients previously considered inoperable or high-risk. Mechanical circulatory support (MCS) devices play a crucial role in stabilizing hemodynamics during percutaneous coronary intervention [...] Read more.
Improved expertise and technological advancements have enabled the safe and effective performance of complex and high-risk-indicated percutaneous coronary intervention (CHIP) in patients previously considered inoperable or high-risk. Mechanical circulatory support (MCS) devices play a crucial role in stabilizing hemodynamics during percutaneous coronary intervention (PCI) -related ischemia, thereby reducing the risk of major adverse events and achieving a more complete revascularization. However, the use of MCS devices in protected PCI is not without risks, including peri-procedural myocardial infarction (MI), bleeding, and access-related complications. Despite numerous observational studies, there is a significant lack of randomized clinical trials comparing different MCS devices in various CHIP scenarios and evaluating their long-term safety and efficacy profiles. This review aims to summarize the current evidence regarding the benefits of MCS devices during CHIPs, offer a practical guide for selecting appropriate devices based on clinical scenarios, and highlight the unanswered questions that future trials need to address. Full article
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28 pages, 4291 KiB  
Review
Innovations in Intracoronary Imaging: Present Clinical Practices and Future Outlooks
by Andreas Mitsis, Christos Eftychiou, Nikolaos P. E. Kadoglou, Konstantinos C. Theodoropoulos, Efstratios Karagiannidis, Athina Nasoufidou, Antonios Ziakas, Stergios Tzikas and George Kassimis
J. Clin. Med. 2024, 13(14), 4086; https://doi.org/10.3390/jcm13144086 - 12 Jul 2024
Cited by 1 | Viewed by 946
Abstract
Engaging intracoronary imaging (IC) techniques such as intravascular ultrasound or optical coherence tomography enables the precise description of vessel architecture. These imaging modalities have well-established roles in providing guidance and optimizing percutaneous coronary intervention (PCI) outcomes. Furthermore, IC is increasingly recognized for its [...] Read more.
Engaging intracoronary imaging (IC) techniques such as intravascular ultrasound or optical coherence tomography enables the precise description of vessel architecture. These imaging modalities have well-established roles in providing guidance and optimizing percutaneous coronary intervention (PCI) outcomes. Furthermore, IC is increasingly recognized for its diagnostic capabilities, as it has the unique capacity to reveal vessel wall characteristics that may not be apparent through angiography alone. This manuscript thoroughly reviews the contemporary landscape of IC in clinical practice. Focused on current methodologies, the review explores the utility and advancements in IC techniques. Emphasizing their role in clarifying coronary pathophysiology, guiding PCI, and optimizing patient outcomes, the manuscript critically evaluates the strengths and limitations of each modality. Additionally, the integration of IC into routine clinical workflows and its impact on decision-making processes are discussed. By synthesizing the latest evidence, this review provides valuable insights for clinicians, researchers, and healthcare professionals involved in the dynamic field of interventional cardiology. Full article
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