Advances in the Diagnosis, Treatment, and Prognosis of Aortic Stenosis
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 1639
Special Issue Editor
Special Issue Information
Dear Colleagues,
Aortic stenosis was first described in 1663 by Lazare Riviere with “ossified” aortic stenosis further delineated by Jean Nicolas Corvisart in the late 18th century.
Aortic stenosis is the most common valvular heart disease diagnosed in Western countries. Patients with a tri-leaflet aortic valve present with calcific aortic stenosis in an older patient population with multiple co-morbidities; however, bicuspid aortic valve disease causes aortic stenosis in a younger population, in which long-term outcomes are especially relevant. Untreated aortic stenosis can progress to heart failure, and subsequent mortality can be high. Unlike other causes of heart failure, no effective medical therapy to prevent or abate aortic stenosis has been identified since it was first described in 1663. As such, aortic valve replacement is the only therapeutic option to impact both the survival and quality of life of these patients. Therefore, it is imperative to identify accurate and innovative methodologies to understand the genetic and acquired etiologies of aortic stenosis. In light of the continually aging population, it is equally as imperative to delineate effective diagnostic and therapeutic strategies to optimize outcomes in all age and economic subpopulations. Models of risk stratification permit timely therapeutic options for both moderate and severe aortic stenosis. This includes clearly defined indications for surgical and transcatheter aortic valve replacement.
The goal of this Special Issue is to highlight novel and innovative approaches to the diagnosis and risk stratification of aortic stenosis to optimize therapeutic strategies including surgical aortic valve replacement (SAVR) and transfemoral aortic valve replacement (TAVR).
Dr. Rita Milewski
Guest Editor
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Keywords
- aortic valve stenosis
- aortic valve replacement
- surgical aortic valve replacement
- transfemoral aortic valve replacement
- risk stratification for aortic stenosis
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