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Clinical Advances in Structural Heart Diseases
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Clinical Advances in Structural Heart Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 943

Special Issue Editor

Dr. Aigul Baltabaeva

E-Mail Website
Guest Editor
1. Department of Cardiology, Harefield Hospital, Guy’s and St Thomas’ NHS Foundation Trust, London UB9 6JH, UK
2. Department of Cardiology, St. Peter’s Hospital, Surrey KT16 0PZ, UK
Interests: cardiac remodeling; valvular heart disease; hypertension; coronary artery disease; heart failure

Special Issue Information

Dear Colleagues,

Welcome to a Special Issue of JCM, dedicated to “Clinical Advances in Structural Heart Diseases”.

Structural heart diseases (SHDs) cover a wide range of congenital and acquired cardiac abnormalities affecting the heart valves, chambers, and associated structures. With new technologies and collaborative efforts, we are witnessing a transformation in how we approach these conditions.

Ground-breaking advances in diagnostics and treatment options in SHD have already made changes in the prognosis and quality of life of thousands of patients. Nevertheless, the rapid pace of evolution and development of devices in transcatheter edge-to-edge valve repair, valve implantations in native and prosthetic positions, and endoscopic surgical interventions are maintained. Interventional echocardiography has become a completely new discipline to reflect the importance of new device applicability in real-life scenarios.

In this issue, we will gather articles addressing recent breakthroughs in diagnosis, treatments, and management strategies with a focus on a multidisciplinary approach. Our contributors, experts in the field, will share insights on the following:

  • Cutting-edge imaging techniques;
  • Advancements in minimally invasive procedures;
  • Comprehensive care.

We hope this collection will serve as a practical resource for clinicians, researchers, and healthcare professionals involved in SHD care. This issue will explore the latest innovations and strive for better outcomes in patient care.

Dr. Aigul Baltabaeva
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • valvular heart disease
  • mitral regurgitation
  • aortic stenosis
  • structural heart disease
  • transcatheter

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Published Papers (1 paper)

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Research

11 pages, 1202 KiB  
Article
Impact of Accidental High or Low Implantation Depth on Peri-Procedural Outcomes after Implantation with the Self-Expanding ACURATE neo2
by Clemens Eckel, Won-Keun Kim, Judith Schlüter, Matthias Renker, Sophie Bargon, Christina Grothusen, Albrecht Elsässer, Guido Dohmen, Yeong-Hoon Choi, Efstratios I. Charitos, Christian W. Hamm, Samuel Sossalla, Helge Möllmann and Johannes Blumenstein
J. Clin. Med. 2024, 13(17), 5342; https://doi.org/10.3390/jcm13175342 - 9 Sep 2024
Viewed by 721
Abstract
Background: Precise implantation could play a crucial role in the technical success of transcatheter aortic valve replacement (TAVR) for some prostheses. The impact of an accidental implantation depth (ID) outside the recommended range has not been assessed for the ACURATE neo2 (NEO2). [...] Read more.
Background: Precise implantation could play a crucial role in the technical success of transcatheter aortic valve replacement (TAVR) for some prostheses. The impact of an accidental implantation depth (ID) outside the recommended range has not been assessed for the ACURATE neo2 (NEO2). Methods: Data from 1839 patients with severe native aortic stenosis treated with the NEO2 prosthesis were evaluated. We compared the results of prostheses implanted in an ID both inside and outside the recommendations. The outcome assessment followed the Valve Academic Research Consortium-3 criteria. Results: Patients were retrospectively divided into high (<3 mm; n = 412), optimal (3–7 mm; n = 1236), and low (>7 mm; n = 169) implantations. Technical success (94.7% vs. 94.7% vs. 91.7%, p = 0.296) and device success were high (90.1% vs. 89.3% vs. 84.6%, p = 0.112) without differences between groups. Rates of relevant paravalvular regurgitation (PVL; >mild or VinV due to PVL) were comparable (1.2% vs. 1.8% vs. 1.2%, p = 0.759). Even when hemodynamics were superior in the high-implantation group, with greater iEOA (1.01 cm2/m2 vs. 0.95 cm2/m2 vs. 0.92 cm2/m2, p < 0.001), spontaneous embolization or after post-dilatation was more common. Low implantation was associated with a higher rate of associated pacemaker implantation (PPI) (6.1% vs. 8.8% vs. 14.8%, p = 0.001). Conclusions: Implantation with the ACURATE neo2 showed excellent hemodynamic results, including low gradients and a small number of relevant PVL, in line with a high technical success rate that was irrespective of the ID. A favorable outcome can also be achieved in accidental low or high positions. Low implantation was associated with a higher rate of associated pacemaker implantation. Deliberately high implantation should be avoided due to the risk of embolization. Full article
(This article belongs to the Special Issue Clinical Advances in Structural Heart Diseases)
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