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Journal of Clinical Medicine, Volume 13, Issue 21

2024 November-1 - 337 articles

Cover Story: Thoracostomy and chest tube placement are essential for treating fluid or air buildup in the pleural cavity. Key historical advancements include closed drainage systems to prevent air entry into the pleural space, the use of plastic materials, and the Heimlich valve. Modern technology offers various chest tube designs (straight, angled, pig-tail) and advanced drainage systems, such as PVC or silicone tubes with radiopaque stripes for improved imaging. Current chest drainage units can incorporate digital systems that monitor and graph pleural pressure and fluid/air removal. Intrapleural therapies, suction, pleurodesis, and long-term indwelling catheters are among the latest applications of chest drain in pleural disease management. View this paper
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Articles (337)

  • Review
  • Open Access
4 Citations
4,517 Views
12 Pages

Outcome Through the Years of Left-Ventricular Assist Devices Therapy for End-Stage Heart Failure: A Review

  • Ilaria Tropea,
  • Giovanni Domenico Cresce,
  • Valerio Sanesi,
  • Loris Salvador and
  • Daniele Zoni

4 November 2024

Heart transplantation remains the gold standard surgical treatment for advanced heart failure. Over time, medical therapies have achieved remarkable outcomes in terms of survival and quality of life, yet their results may be insufficient, even when m...

  • Article
  • Open Access
1 Citations
2,334 Views
10 Pages

The Tinetti Balance Test Is an Effective Predictor of Functional Decline in Non-Hospitalized Post-COVID-19 Individuals: A Cross-Sectional Study

  • Janice R. M. Bastos,
  • Arthur S. Ferreira,
  • Agnaldo J. Lopes,
  • Talita P. Pinto,
  • Erika Rodrigues and
  • Fabio V. dos Anjos

4 November 2024

Background/Objectives: Individuals with post-COVID-19 conditions risk developing short- and/or long-term neuromuscular impairments, including postural imbalance. However, there is limited evidence showing whether balance deficits are associated with...

  • Article
  • Open Access
1 Citations
2,801 Views
14 Pages

Comparison of the Effectiveness of Body Surface Area Estimation Formulas in Predicting the Risk of Death in Patients with Heart Failure

  • Małgorzata Piecuch,
  • Maciej Chylak,
  • Michał Górski,
  • Jagoda Garbicz-Kata,
  • Anna Szczyrba,
  • Marta Buczkowska,
  • Jolanta Malinowska-Borowska,
  • Jolanta Urszula Nowak,
  • Jacek T. Niedziela and
  • Piotr Rozentryt
  • + 1 author

4 November 2024

Background/Objectives: Body surface area is one of the most important anthropometric parameters in medicine. The study’s primary objective is to compare the consistency of the BSA estimation results through applying available formulas. Other ob...

  • Article
  • Open Access
1 Citations
3,022 Views
10 Pages

Molecular Diagnostics for Group A Streptococcal Pharyngitis: Clinical and Economic Benefits in the Belgian Healthcare Context

  • Mohammad Hossein Panahandeh,
  • Reza Soleimani,
  • Yasmine Nezzar,
  • Hector Rodriguez-Villalobos,
  • Benoît Kabamba-Mukadi,
  • Alexandre Grimmelprez and
  • Patricia Schatt

4 November 2024

(1) Background: Group A Streptococcal (GAS) pharyngitis is common, resulting in numerous ambulatory visits. Accurate diagnosis is challenging. This study evaluated the clinical utility, cost, and performance of a nucleic acid amplification test (NAAT...

  • Article
  • Open Access
3 Citations
3,832 Views
14 Pages

4 November 2024

Background/Objectives: Basal cell carcinoma (BCC), the most prevalent form of human cancer, is traditionally treated by surgical and alternative destructive or topical chemical means, each with its advantages, challenges, and drawbacks. We describe o...

  • Article
  • Open Access
2 Citations
1,323 Views
11 Pages

Assessment of Professional Practices in the Care Pathway of Patients with Upper Aerodigestive Tract Cancer in a University Hospital

  • Dounia Chbihi,
  • Morgane Corda,
  • Thomas Thibault,
  • Jérémy Baude,
  • Caroline Guigou and
  • Mireille Folia

4 November 2024

Objectives: The main objective of this study was to evaluate the alignment between treatment decisions made during multidisciplinary team meetings (MTMs) and the treatments received by patients with upper aerodigestive tract cancers. The secondary ob...

  • Feature Paper
  • Review
  • Open Access
24 Citations
25,278 Views
21 Pages

IgA Vasculitis (Henoch–Schönlein Purpura): An Update on Treatment

  • Santos Castañeda,
  • Patricia Quiroga-Colina,
  • Paz Floranes,
  • Miren Uriarte-Ecenarro,
  • Cristina Valero-Martínez,
  • Esther F. Vicente-Rabaneda and
  • Miguel A. González-Gay

4 November 2024

Objective: IgA vasculitis (IgAV), previously named as Henoch–Schönlein purpura, is the most frequent systemic vasculitis in children. In adults, IgAV is less common although it is associated with more severe disease. In fact, the frequency...

  • Article
  • Open Access
2,209 Views
10 Pages

The Triple Procedure in Patients with Congenital Aniridia

  • Bogumił Henryk Wowra,
  • Olga Łach-Wojnarowicz,
  • Marzena Wysocka-Kosmulska,
  • Dariusz Dobrowolski and
  • Edward Wylęgała

4 November 2024

Background: Aniridia is a rare panocular, bilateral, and congenital disease characterized by complete or partial iris hypoplasia and foveal hypoplasia, leading to decreased visual acuity and nystagmus. AAK, also referred to as aniridic keratopathy, m...

  • Article
  • Open Access
1 Citations
2,031 Views
12 Pages

4 November 2024

Background/Objectives: The 28-day mortality rate for septic shock is high, necessitating rapid and effective empiric antimicrobial therapy. In this study, we investigate whether the rate of catecholamine dose reduction in septic shock can indicate ba...

  • Systematic Review
  • Open Access
6 Citations
14,711 Views
35 Pages

Hip Flexor Muscle Activation During Common Rehabilitation and Strength Exercises

  • Jessica Juan,
  • Gretchen Leff,
  • Kate Kevorken and
  • Michael Jeanfavre

4 November 2024

Background/Objectives: The iliopsoas muscle plays an essential role in lumbopelvic and hip anterior stability, which is particularly important in the presence of limited osseous acetabular coverage anteriorly as in hip dysplasia and/or hip micro-inst...

  • Systematic Review
  • Open Access
7 Citations
6,519 Views
28 Pages

Effectiveness of Robotic Devices for Medical Rehabilitation: An Umbrella Review

  • Kei Kiyono,
  • Shigeo Tanabe,
  • Satoshi Hirano,
  • Takuma Ii,
  • Yuki Nakagawa,
  • Koki Tan,
  • Eiichi Saitoh and
  • Yohei Otaka

4 November 2024

Background/Objectives: Clinical trials have investigated the efficacy of rehabilitation robotics for various pathological conditions, but the overall impact on rehabilitation practice remains unclear. We comprehensively examined and analyzed systemat...

  • Article
  • Open Access
2 Citations
1,650 Views
12 Pages

Cirrhosis Progression Is Not Associated with Clinically Significant Alterations in Global Hemostasis Assessed by Thromboelastography

  • Rareș Crăciun,
  • Alina Buliarcă,
  • Daniela Matei,
  • Cristiana Grapă,
  • Iuliana Nenu,
  • Horia Ștefănescu,
  • Tudor Mocan,
  • Bogdan Procopeț and
  • Zeno Spârchez

4 November 2024

(1) Background: Cirrhosis is associated with frequent alterations in standard coagulation tests that do not adequately reflect hemostasis. Thromboelastography provides a global assessment of coagulation and evaluates the functional status of clotting...

  • Article
  • Open Access
2 Citations
1,901 Views
25 Pages

A Multifaceted Exploration of Status Asthmaticus: A Retrospective Analysis in a Romanian Hospital

  • Adriana Ana Trusculescu,
  • Versavia Maria Ancusa,
  • Camelia Corina Pescaru,
  • Norbert Wellmann,
  • Corneluta Fira-Mladinescu,
  • Cristian Iulian Oancea and
  • Ovidiu Fira-Mladinescu

4 November 2024

Background: Status asthmaticus is a severe, life-threatening asthma exacerbation requiring urgent medical intervention. This study aims to examine its epidemiology in Timis County, Romania, over 11 years. Methods: A retrospective analysis was conduct...

  • Hypothesis
  • Open Access
2 Citations
2,695 Views
14 Pages

Intra-Articular Physiological Saline in Temporomandibular Disorders May Be a Treatment, Not a Placebo: A Hypothesis, Systematic Review, and Meta-Analysis

  • Maciej Chęciński,
  • Kamila Chęcińska,
  • Katarzyna Cholewa-Kowalska,
  • Kalina Romańczyk,
  • Dariusz Chlubek and
  • Maciej Sikora

4 November 2024

Background: Intra-articular injections reduce pain in patients with temporomandibular joint (TMJ) disorders who are unresponsive to conservative treatment. Hyaluronic acid, blood products, and medications provide rapid relief when administered this w...

  • Article
  • Open Access
2 Citations
2,682 Views
13 Pages

Applications of Near Infrared Spectroscopy and Mirror Therapy for Upper Limb Rehabilitation in Post-Stroke Patients: A Brain Plasticity Pilot Study

  • Caterina Formica,
  • Simona De Salvo,
  • Nunzio Muscarà,
  • Lilla Bonanno,
  • Francesca Antonia Arcadi,
  • Viviana Lo Buono,
  • Giuseppe Acri,
  • Angelo Quartarone and
  • Silvia Marino

4 November 2024

Objectives: The aim of this study was to identify the neural pattern activation during mirror therapy (MT) and explore any cortical reorganization and reducing asymmetry of hemispheric activity for upper limb rehabilitation in post-stroke patients. M...

  • Review
  • Open Access
3 Citations
4,266 Views
16 Pages

Activation of Irrigants in Root Canals with Open Apices: A Narrative Review

  • Dina Abdellatif,
  • Massimo Pisano,
  • Luigi Cecere,
  • Valentino Natoli,
  • Davide Mancino,
  • Eduard Euvrard and
  • Alfredo Iandolo

4 November 2024

Performing endodontic treatment on a tooth with an immature apex can be challenging due to the risk of irrigant extrusion beyond the apex. This narrative review investigates the over-apex extrusion of activated irrigants in teeth with open and immatu...

  • Article
  • Open Access
4 Citations
2,098 Views
13 Pages

Hemodialysis Experience After Kahramanmaraş Earthquake

  • Bulent Kaya,
  • Mustafa Balal,
  • Neslihan Seyrek,
  • Burak Mete and
  • Ibrahim Karayaylali

4 November 2024

Background: Hemodialysis treatment for acute kidney injury associated with crush syndrome is very complex. In our study, we summarized the problems and complications experienced by our hemodialysis center after the Kahramanmaraş earthquake. Meth...

  • Article
  • Open Access
1,618 Views
9 Pages

Flow-Adjusted Trabeculectomy

  • Assaf Kratz,
  • Ivan Goldberg,
  • Tal Koren,
  • Aviel Hadad,
  • Boris Knyazer and
  • Ridia Lim

4 November 2024

Background/Objectives: As one of the most efficacious glaucoma surgical techniques, trabeculectomy is considered by many surgeons to be the “gold standard” intra-ocular pressure (IOP)-reducing intervention. The purpose of this study is to...

  • Feature Paper
  • Review
  • Open Access
10 Citations
5,116 Views
19 Pages

3 November 2024

Insulin acts on different organs, including the brain, which helps it regulate energy metabolism. Insulin signaling plays an important role in the function of different cell types. In this review, we have summarized the key roles of insulin and insul...

  • Article
  • Open Access
1,474 Views
9 Pages

Dual-Fluoroscopy vs. Single-Fluoroscopy in Balloon Kyphoplasty: A Study of Efficiency and Safety

  • Roy Romem,
  • Itzhak Engel,
  • David Segal,
  • Refael Behrbalk,
  • David Schleifer,
  • Jonathan EJ Koch,
  • Nissim Ohana and
  • Yuval Baruch

3 November 2024

Background: Vertebral compression fractures (VCFs) are the most prevalent type of osteoporotic fractures, often causing significant pain, morbidity, and mortality. Vertebral augmentation procedures like balloon kyphoplasty (BK) are effective in treat...

  • Article
  • Open Access
2,175 Views
10 Pages

3 November 2024

Background: Deranged antepartum laboratory parameters may be risk factors for postpartum hemorrhage (PPH). However, whether this is also valid in women who give birth prematurely is currently unknown. Methods: We performed a retrospective single-cent...

  • Systematic Review
  • Open Access
3 Citations
4,660 Views
17 Pages

Prothrombotic Rebound After Discontinuation of Direct Oral Anticoagulants Therapy: A Systematic Review

  • Marta Frydrych,
  • Maciej Janeczek,
  • Agata Małyszek,
  • Kamil Nelke,
  • Maciej Dobrzyński and
  • Marceli Lukaszewski

3 November 2024

Background/Objectives: The practice of holding anticoagulation is a relatively common approach, with the aim of either preventing excessive bleeding in preparation for surgical procedures or managing acute bleeding episodes. Methods: To assess the re...

  • Article
  • Open Access
8 Citations
4,271 Views
15 Pages

The Effects of an 8-Month Multicomponent Training Program in Body Composition, Functional Fitness, and Sleep Quality in Aged People: A Randomized Controlled Trial

  • Pedro Forte,
  • Samuel G. Encarnação,
  • Luís Branquinho,
  • Tiago M. Barbosa,
  • António M. Monteiro and
  • Daniel Pecos-Martín

3 November 2024

Background/Objectives: This study examined the effects of an intervention on anthropometrics, body composition, physical fitness, and sleep quality in aged individuals, comparing a control group (N = 11) and an experimental group (N = 13) across two...

  • Article
  • Open Access
2 Citations
2,129 Views
9 Pages

Cerebral Overperfusion Despite Reduced Cortical Metabolism Is Associated with Postoperative Delirium in Cardiac Surgery Patients: A Prospective Observational Study

  • Marcus Thudium,
  • Lara Braun,
  • Annika Stroemer,
  • Andreas Mayr,
  • Jan Menzenbach,
  • Thomas Saller,
  • Martin Soehle,
  • Evgeniya Kornilov and
  • Tobias Hilbert

3 November 2024

Background: Decreased cerebral oximetry (rSO2) in cardiac surgery is associated with postoperative delirium (POD). However, interventions optimizing intraoperative rSO2 are inconclusive. Methods: In this prospective observational cohort study, the re...

  • Article
  • Open Access
3 Citations
3,740 Views
10 Pages

3 November 2024

Background: Using intelligent monitoring systems can potentially improve the identification and management of ventilator-associated events (VAEs). This single-center retrospective observational study evaluated the impact of implementing intelligent m...

  • Article
  • Open Access
1 Citations
2,442 Views
13 Pages

A Proton Pump Inhibitor Independently Elevates Gastrin Levels as a Marker for Metachronous Gastric Cancer After Endoscopic Submucosal Dissection

  • Hajime Teshima,
  • Hidehiko Takigawa,
  • Takahiro Kotachi,
  • Akiyoshi Tsuboi,
  • Hidenori Tanaka,
  • Ken Yamashita,
  • Yoshihiro Kishida,
  • Yuji Urabe,
  • Toshio Kuwai and
  • Shiro Oka
  • + 1 author

3 November 2024

Background and Objective: Serum markers such as gastrin and pepsinogen are useful for stratifying gastric cancer risk. However, their utility in predicting metachronous gastric cancer after endoscopic submucosal dissection (ESD) in patients with gast...

  • Article
  • Open Access
1,709 Views
11 Pages

Diagnosis of Enlarged Vestibular Aqueduct Using Wideband Tympanometry

  • Akira Ganaha,
  • Nao Nojiri,
  • Takeshi Nakamura,
  • Teruyuki Higa,
  • Shunsuke Kondo and
  • Tetsuya Tono

3 November 2024

Background: Wideband tympanometry (WBT) has the potential to distinguish various mechanical middle ear and inner ear pathologies noninvasively. This study investigated the diagnostic value of WBT in the diagnosis of enlarged vestibular aqueduct (EVA)...

  • Article
  • Open Access
4 Citations
2,707 Views
10 Pages

An MRI-Based Method for the Morphologic Assessment of the Anterior Tibial Tuberosity

  • Emi Marinela Preda,
  • Nicolae Constantin,
  • Serban Dragosloveanu,
  • Romica Cergan and
  • Cristian Scheau

3 November 2024

Background: A prominent anterior tibial tuberosity (or tibial tubercle) can be seen in ongoing Osgood–Schlatter disease (OSD) in teenagers or as a sequela of OSD in adults. Current radiological methods do not provide a true anatomical assessmen...

  • Article
  • Open Access
1 Citations
4,460 Views
11 Pages

Cholecystectomy Increases the Risk of Chronic Kidney Disease: A Nationwide Longitudinal Cohort Study

  • Ji Hye Heo,
  • Eun Ji Kim,
  • Han Na Jung,
  • Kyung-Do Han,
  • Jun Goo Kang,
  • Seong Jin Lee,
  • Sung-Hee Ihm and
  • Eun Roh

2 November 2024

Background/Objectives: Growing evidence suggests that cholecystectomy is associated with adverse health outcomes, including the development of metabolic diseases. However, data on the association between cholecystectomy and kidney disease are limited...

  • Article
  • Open Access
3 Citations
1,994 Views
12 Pages

The Impact of Neutrophil-to-High-Density Lipoprotein Ratio and Serum 25-Hydroxyvitamin D on Ischemic Heart Disease

  • Ewelina A. Dziedzic,
  • Jakub S. Gąsior,
  • Kamila Koseska,
  • Michał Karol,
  • Ewa Czestkowska,
  • Kamila Pawlińska and
  • Wacław Kochman

2 November 2024

Background: This study describes the complex association between the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR), 25-hydroxyvitamin D (25(OH)D) levels, and cardiovascular disease (CVD), such as stable ischemic heart disease (IHD),...

  • Review
  • Open Access
2 Citations
2,786 Views
12 Pages

2 November 2024

Upper tract urothelial carcinoma (UTUC) accounts for 5–10% of urothelial cancers and is associated with high morbidity and mortality. Increasing incidence of UTUC has been observed since the 1970’s, alongside the evolution of advance imag...

  • Article
  • Open Access
3 Citations
2,588 Views
11 Pages

Long-Term Follow-Up After Non-Curative Endoscopic Submucosal Dissection for Early Gastrointestinal Cancer—A Retrospective Multicenter Analysis

  • Philipp Pimingstorfer,
  • Matus Gregus,
  • Alexander Ziachehabi,
  • Reinhold Függer,
  • Alexander R. Moschen and
  • Rainer Schöfl

2 November 2024

Background: Endoscopic Submucosal Dissection (ESD) has become the standard therapy for early malignant lesions in the gastrointestinal tract and has shown as good oncological surgery results. Approximately 30% of ESDs do not meet the criteria for onc...

  • Article
  • Open Access
2,312 Views
13 Pages

To Treat or to Extract Necrotic First Permanent Molars Between 8 and 12 Years of Age: A Retrospective Cohort Study

  • Valentin Vergier,
  • Pierre-Jean Berat,
  • Anne-Margaux Collignon,
  • Sibylle Vital and
  • Anne-Laure Bonnet

2 November 2024

Background: First permanent molars (FPM) are highly susceptible to decay before the age of 15. When they are severely affected, the decision between conservation and extraction arises, particularly considering the potential for the second permanent m...

  • Case Report
  • Open Access
1,180 Views
7 Pages

2 November 2024

Background: Ruptured pseudoaneurysm of the distal anterior inferior cerebellar artery (AICA) in patients with a history of gamma knife surgery (GKS) for vestibular schwannoma (VS) is rare. Several previous reports have described treatment strategies...

  • Article
  • Open Access
2,068 Views
12 Pages

Hospitalizations of Patients with Atrial Fibrillation (AF) in Poland: A Nationwide Study Based on over One Million AF Hospitalizations in 2017–2021

  • Martyna Dąbrowska,
  • Michał Rząd,
  • Krzysztof Kanecki,
  • Katarzyna Lewtak,
  • Piotr Tyszko,
  • Paweł Goryński and
  • Aneta Nitsch-Osuch

2 November 2024

Background/Objectives: Atrial fibrillation (AF) is one of the most common forms of persistent arrhythmia in adults worldwide. The aim of this study was to present recent data on the epidemiology of patients hospitalized with AF in Poland. Methods: Th...

  • Article
  • Open Access
7 Citations
5,991 Views
12 Pages

2 November 2024

Background: Total hip arthroplasty (THA) is a well-established and effective treatment for advanced osteoarthritis (OA) of the hip joint. While commonly performed in older patients, THA is increasingly used in younger individuals, especially in cases...

  • Article
  • Open Access
2,520 Views
11 Pages

Minimally Invasive Tube Surgery (MITS)—A Novel Method in Glaucoma Drainage Device Implantation

  • Bharpoor Singh,
  • Andrew J. Swampillai,
  • Mrudula Utukuri,
  • Eduardo M. Normando,
  • Ahmed Mazrouaa,
  • Ahmed Al-Nahrawy and
  • Faisal Ahmed

1 November 2024

Background/Objectives: We introduce a new surgical technique for inserting the eyePlate-300—a glaucoma drainage device (GDD). The flexibility of the eyePlate-300 allows for folding and insertion through a smaller conjunctival incision. The proc...

  • Article
  • Open Access
1 Citations
2,358 Views
12 Pages

Clinical and Structural Results Following Arthroscopic and Open Repair of Isolated Subscapularis Tears

  • Christoph Bartl,
  • Janna Dolde,
  • Florian Gebhard,
  • Stefan Eichhorn,
  • Lisa Hainzer and
  • Stephan Pauly

1 November 2024

Objective: With advances in techniques, arthroscopic repair of isolated subscapularis tendon tears has become increasingly popular in recent years. The aim of this study was to analyze the clinical and structural results of arthroscopic repair versus...

  • Systematic Review
  • Open Access
3 Citations
7,628 Views
10 Pages

Safety of Obstetric Ultrasound: Mechanical and Thermal Indexes—A Systematic Review

  • Antonia Varthaliti,
  • Zacharias Fasoulakis,
  • Vasilios Lygizos,
  • Vasiliki Zolota,
  • Maria Ioanna Chatziioannou,
  • Maria Anastasia Daskalaki,
  • George Daskalakis and
  • Panos Antsaklis

1 November 2024

Background/Objectives: Obstetric ultrasound is one of the most commonly used imaging modalities during pregnancy to detect any fetal abnormalities. The aim of this systematic review was to appraise all available scientific literature and summarize cu...

  • Article
  • Open Access
5 Citations
1,702 Views
10 Pages

Hemoperfusion with CytoSorb® in Pediatric Patients: A Monocentric Case Series

  • Eva Rihar,
  • Vanja Peršič,
  • Alexander Jerman,
  • Tina Plankar Srovin,
  • Gorazd Mlakar,
  • Neva Bezeljak,
  • Marko Pokorn and
  • Petja Fister

1 November 2024

Background: Pro- and anti-inflammatory cytokines help regulate the inflammatory response. A cytokine storm is a dysregulated cytokine response associated with sepsis and other conditions that result in a hyper-inflammatory state. Extracorporeal cytok...

  • Review
  • Open Access
2 Citations
2,502 Views
10 Pages

Optimal Use of Drain Tubes for DIEP Flap Breast Reconstruction: Comprehensive Review

  • Bryan Lim,
  • Ishith Seth,
  • Konrad Joseph,
  • Jevan Cevik,
  • Henry Li,
  • Yi Xie,
  • Axel Mendoza Hernandez,
  • Roberto Cuomo and
  • Warren M. Rozen

1 November 2024

Background: Deep inferior epigastric perforator (DIEP) flap breast reconstruction is an increasingly popular technique, but controversy exists regarding the optimal use of closed suction drains (CSD) at the abdominal donor site. This narrative review...

  • Article
  • Open Access
1,969 Views
12 Pages

Discriminating Diseases Mimicking Normal-Tension Glaucoma (NTG) from NTG

  • Hee-Kyung Ryu,
  • Seong-Ah Kim,
  • Hee-Jong Shin,
  • Chan-Kee Park and
  • Hae-Young Lopilly Park

1 November 2024

Background/Objectives: The aim of this study was to identify the most reliable ocular exam and establish a threshold for deciding whether to perform neuroimaging in order to screen for diverse diseases other than normal-tension glaucoma (NTG). A retr...

  • Article
  • Open Access
2 Citations
2,644 Views
12 Pages

Beyond the Surgery: The Impact of Coping Strategies on Persistent Pain After Rotator Cuff Repair

  • Daniela Brune,
  • David Endell,
  • Steven Z. George,
  • Robert Edwards,
  • Markus Scheibel and
  • Asimina Lazaridou

1 November 2024

Background: Rotator cuff repair is widely recognized as one of the most painful orthopedic surgeries, yet postoperative pain management in these patients is often underexplored. This study aimed to explore the relationship between pain outcomes and f...

  • Article
  • Open Access
1 Citations
1,960 Views
8 Pages

Severe Uncontrolled Asthma: A Longitudinal Retrospective Study Illustrating the Experience of the Pulmonology Clinic of Târgu-Mureș, Romania

  • Edith-Simona Ianoși,
  • Dragoș Huțanu,
  • Mara Andreea Vultur,
  • Hédi-Katalin Sárközi,
  • Delia-Liana Rachiș and
  • Gabriela Jimborean

1 November 2024

Introduction: Severe uncontrolled asthma (SUA) affects approximately 5% of asthma patients, leading to frequent exacerbations, reduced lung function, and lower quality of life. Recent biologic therapies target specific inflammatory pathways, offering...

  • Article
  • Open Access
2 Citations
2,997 Views
12 Pages

1 November 2024

Background: With growing concerns about opioid-related risks, efforts to reduce opioid use throughout the perioperative period have increased. This study aimed to compare postoperative recovery outcomes between opioid-free anesthesia (OFA) and opioid...

  • Feature Paper
  • Article
  • Open Access
2,128 Views
9 Pages

Optical Coherence Tomography Study of Choroidal Response to Exercise-Induced Hypertension in Chronic Central Serous Chorioretinopathy

  • Anindya Samanta,
  • Giulia Gregori,
  • Alessio Muzi,
  • Ramkailash Gujar,
  • Cesare Mariotti,
  • Daniela Fruttini,
  • Kiran K. Vupparaboina,
  • Jay Chhablani,
  • Massimo Nicolò and
  • Marco Lupidi
  • + 2 authors

1 November 2024

Background/Objectives: The aim of this study was to evaluate the choroidal vascular response using optical coherence tomography (OCT) in patients with chronic central serous chorioretinopathy (CSCR) during transient increases in blood pressure. Metho...

  • Article
  • Open Access
1,595 Views
13 Pages

Can Artificial Intelligence Help Us in the Evaluation of Coronary Artery Calcification Scores by Acting as a Prognosticator in Patients That Are Operated on Due to Non-Small Cell Lung Cancer? A Pivotal Study

  • Tomasz Marjanski,
  • Michal Chmielecki,
  • Kaja Klein-Awerjanow,
  • Wojciech Cytawa,
  • Patrycja Ciepialowska,
  • Andrii Bilyk,
  • Rafal Peksa and
  • Magdalena Dudek

1 November 2024

Background: Non-small cell lung cancer (NSCLC) is the leading cause of death from malignancies, and surgical resection is the most effective form of treatment. Coronary artery disease (CAD) is a common comorbidity in patients with NSCLC. A coronary a...

  • Review
  • Open Access
42 Citations
4,790 Views
15 Pages

Fecal Microbiota Transplantation: Insights into Colon Carcinogenesis and Immune Regulation

  • Olga Brusnic,
  • Danusia Onisor,
  • Adrian Boicean,
  • Adrian Hasegan,
  • Cristian Ichim,
  • Andreea Guzun,
  • Radu Chicea,
  • Samuel Bogdan Todor,
  • Bogdan Ioan Vintila and
  • Adrian Nicolae Cristian
  • + 4 authors

1 November 2024

Colorectal cancer (CRC) constitutes a significant global health challenge, with recent studies underscoring the pivotal role of the gut microbiome in its pathogenesis and progression. Fecal microbiota transplantation (FMT) has emerged as a compelling...

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J. Clin. Med. - ISSN 2077-0383