Advances in Pediatric Otorhinolaryngology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 21457

Special Issue Editors


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Guest Editor
Department of Clinical Sciences and Community Health, Ospedale Maggiore Policlinico Pad. Monteggia, Milan, Italy
Interests: infectious otolaryngology; pediatric otolaryngology; rhinosinusitis
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy
2. Fondazione I.R.C.C.S. Ca’ Granda Policlinico, Milan, Italy
Interests: pediatric otolaryngology; head and neck surgery; salivary gland disease
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Clinical Sciences and Community Health, Ospedale Maggiore Policlinico - Pad. Monteggia, Milan, Italy
Interests: pediatric otolaryngology; head and neck cancer; head and neck surgery

E-Mail Website
Guest Editor
1. Department of Otolaryngology and Head and Neck Surgery, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
2. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
Interests: pediatric otolaryngology; head and neck surgery; endoscopic surgery; ear surgery; salivary disease; airway surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Pediatric otorhinolaryngological disorders are frequently encountered in clinical practice, sometimes requiring an undesired surgical proposal after an adequate but challenging comprehensive diagnostic workup.

Recurrences of chronic infectious processes sustained by bacterial biofilm or impairment in the respiratory microbiota are troublesome situations requiring the adoption of new diagnostic and therapeutic options in order to avoid surgery. Moreover, technological advances, in particular in the field of optic endoscopic systems, favor the transition from traditional invasive surgery to minimally invasive surgical modalities to treat children with otorhinolaryngological diseases. In addition, the ongoing COVID-19 pandemic has upset our routine clinical practice, leading, on the one hand, to a delay in the treatment of some patients, and, on the other hand, to a significant modification of the natural history of the disease, attested to by a consistent reduction in the number of acute exacerbations as previously documented in otitis-prone children during the lockdown.

We invite authors to contribute to this Special Issue of the Journal of Clinical Medicine (PubMed indexed) with articles focusing on any new topic dealing with the pathogenesis, diagnosis, and treatment of otorhinolaryngological disorders in children and the modification of clinical protocols and strategies during the ongoing COVID-19 pandemic.

Prof. Sara Torretta
Prof. Pasquale Capaccio
Prof. Pignataro Lorenzo
Dr. Michele Gaffuri
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • otolaryngology
  • children
  • infection
  • otitis
  • salivary gland disease
  • adenoid
  • covid
  • airway

Published Papers (9 papers)

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10 pages, 1181 KiB  
Article
Intrapatient Comparison of Coblation versus Electrocautery Tonsillectomy in Children: A Randomized, Controlled Trial
by Kyu Young Choi, Jae-Cheul Ahn, Chae-Seo Rhee and Doo Hee Han
J. Clin. Med. 2022, 11(15), 4561; https://doi.org/10.3390/jcm11154561 - 4 Aug 2022
Cited by 3 | Viewed by 1995
Abstract
Many surgical instruments have been introduced and compared for safety and surgical efficiency in tonsillectomy. This study aimed to compare postoperative pain between coblation and conventional monopolar electrocautery tonsillectomy by intrapatient comparison in children. Thirty pediatric patients over six years of age undergoing [...] Read more.
Many surgical instruments have been introduced and compared for safety and surgical efficiency in tonsillectomy. This study aimed to compare postoperative pain between coblation and conventional monopolar electrocautery tonsillectomy by intrapatient comparison in children. Thirty pediatric patients over six years of age undergoing tonsillectomies were enrolled. Coblation and electrocautery were used to remove both tonsils in one patient; one was removed by coblation and the other by electrocautery. The coblation side was randomly selected, and it was blinded to the patients. Each side’s daily pain scores were collected on the visual analogue scale (VAS) during ten postoperative days. On the day of surgery, 22 (73%) patients identified less pain on the coblation side, while others felt similar pain. The mean pain scores were significantly lower on the coblation side during the postoperative ten days (except for the 6th and 8th) than on the electrocautery side. The duration of severe pain (VAS > 5) was significantly shorter on the coblation side than on the electrocautery side (2.0 versus 3.7 days, respectively; p = 0.042). Coblation tonsillectomy induced less pain than electrocautery in pediatric patients; therefore, surgeons could choose the coblator as a surgical instrument for tonsillectomy to improve the pediatric postoperative quality of life. Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
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10 pages, 873 KiB  
Article
Predictors of Surgical Intervention for Pediatric Acute Rhinosinusitis with Periorbital Infection
by Pei-Wen Wu, Yen-Ling Lin, Yun-Shien Lee, Cheng-Hsun Chiu, Ta-Jen Lee and Chien-Chia Huang
J. Clin. Med. 2022, 11(13), 3831; https://doi.org/10.3390/jcm11133831 - 1 Jul 2022
Cited by 2 | Viewed by 1390
Abstract
Background: Medical versus surgical management of pediatric periorbital infection secondary to acute bacterial rhinosinusitis (ABRS) can be a dilemma for clinicians. This study aimed to evaluate the prognostic factors related to the need for surgical drainage and to help direct management decisions. Methods: [...] Read more.
Background: Medical versus surgical management of pediatric periorbital infection secondary to acute bacterial rhinosinusitis (ABRS) can be a dilemma for clinicians. This study aimed to evaluate the prognostic factors related to the need for surgical drainage and to help direct management decisions. Methods: Children admitted for periorbital infection secondary to ABRS between 2001 and 2019 were retrospectively reviewed. Demographics, clinical presentations, laboratory data, comorbidities, and computed tomography results were collected from medical records. Results: A total of 141 pediatric patients were enrolled. Forty-two patients (29.8%) required surgical intervention. Multivariate logistic regression analysis identified that delayed initiation of intravenous antibiotics from the onset of periorbital swelling (odds ratio [OR] = 1.94; p < 0.001) and proptosis at initial presentation (OR = 6.63; p = 0.008) were significantly associated with the need for surgical intervention. A C-reactive protein value of > 55.73 mg/L and initiation of intravenous antibiotic treatment > 2 days from the onset of periorbital swelling showed the best predictive power for surgery. Conclusions: Pediatric patients with delayed initiation of intravenous antibiotic treatment and initial presentation of proptosis had worse outcomes and required surgical intervention. Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
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11 pages, 850 KiB  
Article
The Effect of Pre-Emptive Analgesia on the Postoperative Pain in Pediatric Otolaryngology: A Randomized, Controlled Trial
by Jakub Zieliński, Monika Morawska-Kochman, Krzysztof Dudek, Michał Czapla and Tomasz Zatoński
J. Clin. Med. 2022, 11(10), 2713; https://doi.org/10.3390/jcm11102713 - 11 May 2022
Cited by 4 | Viewed by 2053
Abstract
The aim of this randomized, controlled trial was to determine whether children undergoing otolaryngological procedures (adenoidectomy, adenotonsillotomy, or tonsillectomy) benefit from pre-emptive analgesia in the postoperative period. Methods: Fifty-five children were assessed for eligibility for the research. Four children refused to participate during [...] Read more.
The aim of this randomized, controlled trial was to determine whether children undergoing otolaryngological procedures (adenoidectomy, adenotonsillotomy, or tonsillectomy) benefit from pre-emptive analgesia in the postoperative period. Methods: Fifty-five children were assessed for eligibility for the research. Four children refused to participate during the first stage of the study, leaving fifty-one (n = 51) to be randomly assigned either to receive pre-emptive analgesic acetaminophen (15 mg/kg; n = 26) or a placebo (n = 25) in addition to midazolam (0.5 mg/kg) as premedication. All children were anesthetized with sevoflurane, propofol (2–4 mg/kg), and fentanyl (2 mcg/kg). Postoperative pain was assessed using the Visual Analogue Scale (VAS), the Wong–Baker Faces Pain Rating Scale, and the Face, Legs, Activity, Cry, and Consolability (FLACC) scale. The postoperative pain was measured 1, 2, 4, and 6 h after the surgery. Results: The clinical trial reported a statistically significant correlation between administering pre-emptive analgesia (acetaminophen) and reducing pain in children after otolaryngological procedures compared to placebo. The ratio of boys to girls and age were similar among the groups (p > 0.05), so the groups of children were not divided by gender or age. Conclusions: Standard pre-emptive analgesia reduced the severity of pain in the postoperative period after otolaryngological procedures in children. Acetaminophen given before surgery reduces postoperative pain in children undergoing otolaryngological procedures. Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
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14 pages, 1630 KiB  
Article
The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children
by Aleksander Zwierz, Krystyna Masna, Krzysztof Domagalski and Paweł Burduk
J. Clin. Med. 2022, 11(3), 507; https://doi.org/10.3390/jcm11030507 - 20 Jan 2022
Cited by 10 | Viewed by 5972
Abstract
Background: The purpose of this study is to analyse the long-term effects of a 12-week course of topical steroids on adenoid size and its mucus using endoscopy and on middle ear effusion measured by tympanometry. Methods: The study presents an endoscopic choanal assessment [...] Read more.
Background: The purpose of this study is to analyse the long-term effects of a 12-week course of topical steroids on adenoid size and its mucus using endoscopy and on middle ear effusion measured by tympanometry. Methods: The study presents an endoscopic choanal assessment of the change in adenoid size (adenoid to choanae ratio, A/C ratio) and its mucus coverage in 165 children with Grade II and III adenoid hypertrophy three to six months after finishing a 12-week course of intranasal steroid treatment with mometasone furoate. Additionally, tympanometry was performed to measure middle ear effusion. Changes in the tympanograms were analysed. Results: The mean A/C ratio before treatment was 65.73%. Three to six months after finishing a 12-week course of intranasal steroid treatment, the mean A/C ratio decreased to 65.52%, although the change was not statistically significant (p = 0.743). There was no change in adenoid mucus according to the MASNA scale before and three to six months after the end of the steroid treatment (p = 0.894). Long-term observations of tympanograms before and three to six months after the end of the treatment did not show improvement (p = 0.428). Conclusions: The results indicate that there was no effect of topical steroids on adenoid size, its mucus and otitis media with effusion (OME) three to six months after finishing a 12-week course of treatment. In the light of performed study, decision of adenoidectomy and tympanostomy should not be procrastinated. Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
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11 pages, 550 KiB  
Article
The Impact of the Thermal Seasons on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study
by Krystyna Masna, Aleksander Zwierz, Krzysztof Domagalski and Paweł Burduk
J. Clin. Med. 2021, 10(23), 5603; https://doi.org/10.3390/jcm10235603 - 28 Nov 2021
Cited by 12 | Viewed by 3148
Abstract
Background: The purpose of this study is to analyze seasonal differences in adenoid size and related mucus levels via endoscopy, as well as to estimate changes in middle ear effusion via tympanometry. Methods: In 205 children with adenoid hypertrophy, endoscopic choanal assessment, adenoid [...] Read more.
Background: The purpose of this study is to analyze seasonal differences in adenoid size and related mucus levels via endoscopy, as well as to estimate changes in middle ear effusion via tympanometry. Methods: In 205 children with adenoid hypertrophy, endoscopic choanal assessment, adenoid hypertrophy assessment using the Bolesławska scale, and mucus coverage assessment using the MASNA scale were performed in two different thermal seasons, summer and winter. The study was conducted in two sequences of examination, summer to winter and winter to summer, constituting two separate groups. Additionally, in order to measure changes in middle ear effusion, tympanometry was performed. Results: Overall, 99 (48.29%) girls and 106 (51.71%) boys, age 2–12 (4.46 ± 1.56) were included in the study. The first group, examined in summer (S/W group), included 100 (48.78%) children, while the group first examined in winter (W/S group) contained 105 (51.22%) children. No significant relationship was observed between the respective degrees of adenoid hypertrophy as measures by the Bolesławska scale between the S/W and W/S groups in winter (p = 0.817) and in summer (p = 0.432). The degrees of mucus coverage of the adenoids using the MASNA scale and tympanograms were also comparable in summer (p = 0.382 and p = 0.757, respectively) and in winter (p = 0.315 and p = 0.252, respectively) between the S/W and W/S groups. In the total sample, analyses of the degrees of adenoid hypertrophy using the Bolesławska three-step scale for seasonality showed that patients analysed in the summer do not differ significantly when compared to patients analysed in the winter (4.39%/57.56%/38.05% vs. 4.88%/54.63%/40.49%, respectively; p = 0.565). In contrast, the amount of mucus on the adenoids increased in winter on the MASNA scale (p = 0.000759). In addition, the results of tympanometry showed deterioration of middle ear function in the winter (p = 0.0000149). Conclusions: The obtained results indicate that the thermal seasons did not influence the size of the pharyngeal tonsils. The increase and change in mucus coverage of the adenoids and deterioration of middle ear tympanometry in winter may be the cause of seasonal clinical deterioration in children, rather than tonsillar hypertrophy. The MASNA scale was found to be useful for comparing endoscopy results. Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
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9 pages, 2255 KiB  
Article
Clinical Prognostic Factors Associated with Good Outcomes in Pediatric Bell’s Palsy
by Myung Chul Yoo, Dong Choon Park, Jae Yong Byun and Seung Geun Yeo
J. Clin. Med. 2021, 10(19), 4368; https://doi.org/10.3390/jcm10194368 - 24 Sep 2021
Cited by 1 | Viewed by 1788
Abstract
The prognosis of children with Bell’s palsy remains unclear due to its relatively low incidence, and thus, the small number of patients included in individual studies. To evaluate the prognosis of children with Bell’s palsy and identify the predictive value of specific factors [...] Read more.
The prognosis of children with Bell’s palsy remains unclear due to its relatively low incidence, and thus, the small number of patients included in individual studies. To evaluate the prognosis of children with Bell’s palsy and identify the predictive value of specific factors that contribute to complete recovery, a retrospective cohort study was conducted of all patients with Bell’s palsy who visited the outpatient clinic of our university hospital between January 2005 and December 2020. We identified the parameters associated with a favorable recovery after 6 months in pediatric patients with Bell’s palsy. Factors recorded for each patient included age, sex, side affected by palsy, time between symptom onset and start of treatment, treatment methods, and the House–Brackmann grade (H–B) grade. The results of the multivariable analysis revealed that the lower degree of initial facial nerve paralysis presented as H–B grade II–IV was a significant favorable prognostic factor (OR: 3.86; 95% CI: 1.27–11.70; p < 0.05). Our results showed that the most important factor influencing the complete recovery of Bell’s palsy in children was the lower initial H–B grade at initial presentation. Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
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2 pages, 187 KiB  
Reply
Reply to Kalfert, D. Comment on “Zwierz et al. The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children. J. Clin. Med. 2022, 11, 507”
by Aleksander Zwierz
J. Clin. Med. 2022, 11(9), 2270; https://doi.org/10.3390/jcm11092270 - 19 Apr 2022
Viewed by 1068
Abstract
We wish to thank the author for raising the issues of how we performed the adenoid size classification and why we did not classify the condition of the nasopharyngeal orifice of the Eustachian tube [...] Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
1 pages, 182 KiB  
Comment
Comment on Zwierz et al. The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children. J. Clin. Med. 2022, 11, 507
by David Kalfert
J. Clin. Med. 2022, 11(7), 1983; https://doi.org/10.3390/jcm11071983 - 2 Apr 2022
Cited by 1 | Viewed by 1059
Abstract
I read with great interest the article entitled “The Long-Term Effects of 12-Week Intranasal Steroid Therapy on Adenoid Size, Its Mucus Coverage and Otitis Media with Effusion: A Cohort Study in Preschool Children” by Zwierz et al. [...] Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
8 pages, 454 KiB  
Brief Report
Has Otitis Media Disappeared during COVID-19 Pandemic? A Fortuitus Effect of Domestic Confinement
by Sara Torretta, Barbara Cantoni, Giuseppe Bertolozzi, Pasquale Capaccio, Gregorio Paolo Milani, Lorenzo Pignataro, Sebastiano Aleo and Paola Marchisio
J. Clin. Med. 2021, 10(13), 2851; https://doi.org/10.3390/jcm10132851 - 27 Jun 2021
Cited by 20 | Viewed by 1973
Abstract
Background: To measure patient flow at our Pediatric Emergency Department (PED) during the Italian lockdown, with particular care in terms of otolaryngological (ENT)-related diagnoses. Methods: A retrospective evaluation of electronic charts of children admitted to our PED in the City Center of Milan [...] Read more.
Background: To measure patient flow at our Pediatric Emergency Department (PED) during the Italian lockdown, with particular care in terms of otolaryngological (ENT)-related diagnoses. Methods: A retrospective evaluation of electronic charts of children admitted to our PED in the City Center of Milan (Italy) for any disease. The outcome was to compare distribution of diagnoses performed at our PED during 21 February–3 May 2019 (period 1) to 21 February–3 May 2020 (period 2). Results: A total of 4538 children were evaluated during period 1 compared to 1310 during period 2. A statistically significant overall effect on diagnosis between the study periods was attested (p-value < 0.001; pseudo R2 = 0.010), ENT-related diagnoses being more frequently documented in period 1 (80.4% vs. 19.5%; p-value < 0.001), as well as those related to middle ear infections (92.8% vs. 7.2%; p-value < 0.001). Non-complicated acute otitis media more frequently occurred in period 1 (92.0% vs. 8.0%; p-value < 0.001); no significant difference in the number of complicated middle ear infections occurred (95.8% vs. 4.2%). Conclusions: The exceptional circumstances of the Italian lockdown resulted in a significant decrease in patients’ attendance to our PED, especially when considering diagnoses related to any ENT disorder, middle ear disease, and non-complicated middle ear infection. Full article
(This article belongs to the Special Issue Advances in Pediatric Otorhinolaryngology)
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