Clinical Updates and Perspectives on Subarachnoid Hemorrhage

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 20 April 2025 | Viewed by 114

Special Issue Editor


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Guest Editor
Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan
Interests: subarachnoid hemorrhage; outcome of subarachnoid hemorrhage; delayed cerebral ischemia, ruptured cerebral aneurysm; unruptured cerebral aneurysm; artificial intelligence

Special Issue Information

Dear Colleagues,

Subarachnoid hemorrhage (SAH) is a severe condition with a mortality rate of approximately 35%. However, unlike ischemic stroke, the treatment outcomes for SAH have not significantly improved. The management of post-SAH brain injury and delayed cerebral ischemia (DCI) remains inadequate. The prognosis of SAH is influenced not only by the neurological severity at onset and surgical outcomes but also by the occurrence of delayed cerebral ischemia. Therefore, improving the treatment of DCI is crucial for enhancing the prognosis of SAH.

The etiology of DCI following SAH involves not only cerebral vasospasm but also primary brain injury, increased intracranial pressure, microcirculatory disturbances, microthrombosis, blood–brain barrier disruption, and cortical spreading ischemia. Therefore, a comprehensive prevention and treatment strategy is essential.

Japan has a higher incidence of SAH compared to the global average, suggesting that preventive measures against SAH in Japan may be insufficient. Risk factors for SAH include hypertension, smoking, alcohol abuse, and the use of certain drugs. Factors more prevalent among the Japanese population include genetics, aging, high smoking rates, and a higher detection rate of SAH, though these are not definitively identified.

This Special Issue calls for original research utilizing novel data to address the aforementioned issues.

Dr. Fusao Ikawa
Guest Editor

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Keywords

  • subarachnoid hemorrhage
  • outcome of subarachnoid hemorrhage
  • delayed cerebral ischemia,
  • ruptured cerebral aneurysm
  • unruptured cerebral aneurysm
  • artificial intelligence
  • epidemiology

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