Latest Advances in Lower Urinary Tract Symptoms and Pelvic Floor Dysfunction Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 6 November 2024 | Viewed by 493

Special Issue Editors


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Guest Editor
Department of Obstetrics and Gynecology, Clinical Division of General Gynecology and Gynecologic Oncology, Medical University of Vienna, 1090 Vienna, Austria
Interests: microbiome; urinary incontinence; overactive bladder syndrome; stress urinary incontinence; postpartum pelvic floor disorders

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Guest Editor
1. Department of Urogynaecology, LNWH NHS Trust, London, UK
2. Department of Epidemiology & Biostatistics, Imperial College London, London, UK
Interests: fibroids; heavy periods; gender affirmation surgery; incontinence; ovarian cysts; pelvic floor reconstructive surgery; prolapse; urinary tract infection

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Guest Editor
Department of Obstetrics and Gynaecology, Jeroen Bosch Hospital, Den Bosch, The Netherlands
Interests: postpartum pelvic floor disorder; obstetric defaecation; obstetric anal sphincter

Special Issue Information

Dear Colleagues,

This Special Issue aims to address the pressing issues surrounding female lower urinary tract symptoms (LUTSs), including pelvic organ prolapse (POP) and urinary incontinence (UI). Despite significant advancements in research, there remain core problems to be solved, such as understanding the multifactorial etiology of these conditions, improving diagnostic accuracy and refining treatment modalities to enhance patient outcomes. In the current era in which women grow older, there will be more women suffering from pelvic floor disease. They will increasingly rely on healthcare as they are motivated to continue their work, informal care and leisure time. The increasing costs associated with healthcare and the reduction in the number of healthcare professionals mean that we need to treat all women in a suitable manner, including the need for prevention. The scope of this Special Issue encompasses a broad array of topics, including, but not limited to, epidemiology, pathophysiology, risk factors, diagnostic techniques, treatment strategies and patient outcomes related to female LUTSs. By mobilizing contributions from diverse research disciplines, including gynecology and obstetrics, urology, physiotherapy, general surgery and basic science, this Special Issue seeks to foster interdisciplinary collaboration and knowledge exchange, ultimately advancing our understanding and management of these complex and prevalent conditions in women.

Dr. Marianne Koch
Dr. Rufus Cartwright
Dr. Kim W.M. Van Delft
Guest Editors

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Keywords

  • pelvic organ prolapse
  • urinary incontinence
  • overactive bladder syndrome
  • stress urinary incontinence
  • postpartum pelvic floor dysfunction
  • bladder dysfunction
  • obstetric anal sphincter injury
  • lower urinary tract dysfunction

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Published Papers (1 paper)

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Research

9 pages, 1009 KiB  
Article
Explorative Identification of Anatomical Parameters Associated with Successful Pessary Fitting in Pelvic Organ Prolapse Using Dynamic Magnetic Resonance Imaging
by Charlotte P. R. Triepels, Lars L. Boogaard, Jurgen J. Fütterer, Sander M. J. van Kuijk, Wilbert A. Spaans, Roy F. P. M. Kruitwagen, Mirjam Weemhoff and Kim J. B. Notten
J. Clin. Med. 2024, 13(16), 4819; https://doi.org/10.3390/jcm13164819 - 15 Aug 2024
Viewed by 251
Abstract
Background: Pelvic organ prolapse (POP) affects many women and is often managed with pessary treatment, yet predicting the success of fitting remains challenging. This study aims to identify anatomical parameters associated with successful and unsuccessful pessary treatment using dynamic magnetic resonance imaging (dMRI). [...] Read more.
Background: Pelvic organ prolapse (POP) affects many women and is often managed with pessary treatment, yet predicting the success of fitting remains challenging. This study aims to identify anatomical parameters associated with successful and unsuccessful pessary treatment using dynamic magnetic resonance imaging (dMRI). Methods: A cross-sectional study in Maastricht University Medical Centre (MUMC+), the Netherlands. Sixteen women with a cystocele and/or descensus uteri minimal POP-Q stage 2, using pessary treatment, were included. All women underwent a dynamic MRI of the pelvic floor at rest, during contraction and on Valsalva. The anatomical parameters evaluated included various lengths and angles. The association between the anatomical parameters and pessary fitted is assessed using partial least squares regression. The predictive accuracy was tested using cross-validation based on the partial least squares model with the most important variables. Results: Seven of the sixteen women (43.8%) were in the non-fitting group (due to movement, rotation or expulsion of the pessary), and nine women (56.3%) were in the fitting group. Participants in the non-fitting group had a significantly lower body mass index (BMI). Variables such as total vaginal length (TVL) and certain angles were highly predictive of pessary fitting success, with variable importance of projection (VIP) scores indicating their importance. The prediction models showed accuracies ranging from 53.3% to 80.0%. Conclusions: In this explorative study, TVL, cervical length (CL), sacrococcygeal angle and pubococcygeal angle were key variables associated with pessary fitting success. These findings offer valuable insights for optimizing pessary fitting procedures and the development of new pessaries. Full article
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