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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Aortic Dissection: Current Trends, Complexities, and Future Directions

edited by Aung Ye Oo

submission deadline 15 Jul 2026 | 1 articles | Viewed by 920 | Submission Open

Keywords: aortic dissection; aortic surgery; hybrid and endovascular repair; diagnostic delay; systems of care; patient safety; biomarkers and imaging; postoperative outcomes; multidisciplinary collaboration in aortic disease management

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Updates on Epilepsy Research

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jul 2026 | 2 articles | Viewed by 807 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Glaucoma: Advances in Diagnosis, Management, and Vision Preservation

edited by

Masaki Tanito

and

Takuhei Shoji

submission deadline 15 Jul 2026 | 1 articles | Viewed by 696 | Submission Open

Keywords: glaucoma diagnosis; OCT and OCT angiography; laser therapies (SLT; micropulse; cyclophotocoagulation; etc.); minimally invasive glaucoma surgery (MIGS); long-tube devices; artificial intelligence and imaging; pharmacological therapy; visual field and retinal ganglion cell function

(This special issue belongs to the Section Ophthalmology)

Minimally Invasive Cardiothoracic Surgery: Current Status and Future Perspectives

edited by

Shun-Ichiro Sakamoto

submission deadline 15 Jul 2026 | 1 articles | Viewed by 694 | Submission Open

Keywords: aortic-preserving surgery; hybrid cardiovascular surgery; autologous tissue repair; enhanced recovery after surgery; minimally invasive cardiac surgery (MICS); geriatric surgery

(This special issue belongs to the Section Cardiovascular Medicine)

Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options

edited by Przemysław Puz,

Nikolaos Grigoriadis

and

Eduardo Agüera-Morales

submission deadline 15 Jul 2026 | 2 articles | Viewed by 684 | Submission Open

Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection

(This special issue belongs to the Section Clinical Neurology)

Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment

edited by

Nicholas David Clement

submission deadline 15 Jul 2026 | Viewed by 263 | Submission Open

Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment

(This special issue belongs to the Section Orthopedics)

Novel Therapeutic Strategies in Rheumatoid Arthritis

edited by Mislav Radić

submission deadline 15 Jul 2026 | Viewed by 213 | Submission Open

Keywords: rheumatoid arthritis; targeted therapies; biological agents; small molecule inhibitors; biomarkers; personalized medicine; treatment response

(This special issue belongs to the Section Immunology & Rheumatology)

New Challenges and Perspectives in Polycystic Ovary Syndrome/Polyendocrine Metabolic Ovarian Syndrome: 2nd Edition

edited by

Jim Parker

submission deadline 15 Jul 2026 | Viewed by 187 | Submission Open

Keywords: polycystic ovary syndrome; evolutionary origins; developmental origins; pathogenesis; pathophysiology; microbiome; pregnancy complications; lifestyle

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Challenges and Advancements in Stroke Prevention and Cerebrovascular Disorders

edited by

Ewelina Bak

and Sylwia Krzemińska

submission deadline 15 Jul 2026 | Viewed by 174 | Submission Open

Keywords: risk factors; secondary prevention; health education; health behaviors

(This special issue belongs to the Section Clinical Rehabilitation)

Personalized Medicine for the Management of Non-Communicable Disease (NCDs)

edited by

Alessandro Mattina

, Giulio Geraci and

Vincenzina Lo Re

submission deadline 16 Jul 2026 | 11 articles | Viewed by 24033 | Submission Open

Keywords: personalized medicine; precision medicine; non-communicable disease; cardiovascular disease; cancer; diabetes; chronic obstructive pulmonary disease; cognitive impairment; atherosclerosis; lipids; inflammation; immunity; therapy

(This special issue belongs to the Section Epidemiology & Public Health)

Plastic Surgery: Challenges and Future Directions

edited by Philip Brazio and Edward C. Ray

submission deadline 20 Jul 2026 | 7 articles | Viewed by 19922 | Submission Open

Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Artificial Intelligence (AI) and Deep Learning (DL) in Medical Imaging

edited by

Francesco Pucciarelli

submission deadline 20 Jul 2026 | 6 articles | Viewed by 13697 | Submission Open

Keywords: artificial intelligence; deep learning; imaging; diagnosis; precision medicine; oncologic

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Advances and Perspectives in Cancer Diagnostics and Treatment

edited by Alexandru E. Eniu,

Cristina Marinela Oprean

and

Simona Ruxandra Volovat

submission deadline 20 Jul 2026 | 9 articles | Viewed by 13484 | Submission Open

Keywords: solid tumors; new advances; diagnostics and treatment; clinical– pathological; genetic factors; AI; RWD; radiotherapy; biomarkers; prevention in cancer care; target therapy; immunotherapy

(This special issue belongs to the Section Oncology)

Insights and Innovations in Sports Cardiology

edited by

Garyfallia K. Pepera

submission deadline 20 Jul 2026 | 6 articles | Viewed by 11263 | Submission Open

Keywords: sports cardiology; athlete heart; cardiovascular screening; arrhythmias; sudden cardiac death; cardiac rehabilitation; exercise prescription; mobile health; preventive cardiology; personalized medicine; pediatric fitness

(This special issue belongs to the Section Sports Medicine)

Clinical Guidelines in Critical Care Medicine

edited by

Ana Vujaklija Brajković

Andrej Markota

and Daniela Bandic-Pavlovic

submission deadline 20 Jul 2026 | 4 articles | Viewed by 10902 | Submission Open

Keywords: critical illness; immunocompromised host; biomarkers; thrombocytopenia; blood coagulation disorders; multiple trauma; diagnostic imaging

(This special issue belongs to the Section Intensive Care)

Foot and Ankle Surgery: Current Advances and Prospects

edited by

Jaeho Cho

submission deadline 20 Jul 2026 | 8 articles | Viewed by 10872 | Submission Open

Keywords: foot and ankle surgery; foot pathologies; ankle disease and trauma; diabetic foot; epidemiology; clinical anatomy; foot orthoses; weight-bearing CT

(This special issue belongs to the Section Orthopedics)

Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome

edited by

Razvan Ionut Ghinea

Ioana-Sofia Pop-Ciutrilă

and

Luminita-Maria Nica

submission deadline 20 Jul 2026 | 4 articles | Viewed by 10108 | Submission Open

Keywords: endodontics; apical periodontitis; pulpitis; root canal treatment; risk factors; treatment outcomes; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiac Arrhythmias: Current Status and Future Directions

edited by

Jackson J. Liang

submission deadline 20 Jul 2026 | 1 articles | Viewed by 9358 | Submission Open

Keywords: ventricular tachycardia; atrial fibrillation; catheter ablation; novel therapies; complex arrhythmias

(This special issue belongs to the Section Cardiology)

Acute Myocardial Infarction: Diagnosis, Treatment, and Rehabilitation

edited by

Francesca Giordana

submission deadline 20 Jul 2026 | 8 articles | Viewed by 9249 | Submission Open

Keywords: acute myocardial infarction; coronary angioplasty; acute heart failure; cardiogenic shock; rehabilitation programs

(This special issue belongs to the Section Cardiovascular Medicine)

State of the Art in Hand Surgery

edited by Leszek Romanowski and

Piotr Czarnecki

submission deadline 20 Jul 2026 | 5 articles | Viewed by 9057 | Submission Open

Keywords: hand surgery; nerve surgery; state-of-the-art; hand therapy; tendons; thumb arthritis; hand fractures

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Sustaining Success Through Innovation in Kidney Transplantation

edited by Junji Uchida

submission deadline 20 Jul 2026 | 7 articles | Viewed by 8891 | Submission Open

Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Autoimmune Disorders

edited by

Chiara Pellicano

and

Edoardo Rosato

submission deadline 20 Jul 2026 | 6 articles | Viewed by 8681 | Submission Open

Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition

edited by

Silvia Cimino

submission deadline 20 Jul 2026 | 4 articles | Viewed by 8560 | Submission Open

Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver– patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support

(This special issue belongs to the Section Intensive Care)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 20 Jul 2026 | 4 articles | Viewed by 8408 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

Interventional Cardiology—Challenges and Solutions

edited by

Yonggu Lee

submission deadline 20 Jul 2026 | 5 articles | Viewed by 8331 | Submission Open

Keywords: chronic total occlusion; highly calcified coronary or lower extremity arteries; stentless percutaneous coronary intervention; chronic limb threatening ischemia; instent restenosis in the extremity artery diseases; endovascular therapy for pulmonary thromboembolism; transcatheter aortic valve replacemment for the bicuspid aortic valve; transcatheter aortic valve replacement for the valve-in-valve procedure; endovascular therapy for tricospid valve regurgitation; transcatheter edge-to-edge repair for mitral valve regurgitation

(This special issue belongs to the Section Cardiovascular Medicine)

Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies

edited by

Ralph Mösges

submission deadline 20 Jul 2026 | 5 articles | Viewed by 8196 | Submission Open

Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT

(This special issue belongs to the Section Immunology & Rheumatology)

Inflammatory Bowel Diseases: Clinical Advances and Emerging Therapies

edited by

Ewa Malecka-Wojciesko

submission deadline 20 Jul 2026 | 5 articles | Viewed by 6556 | Submission Open

Keywords: inflammatory bowel disease (IBD); ulcerative colitis; Crohn’ s disease; gut inflammation; bowel perforation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Glaucoma Surgery: Current Challenges and Future Perspectives

edited by

Tina Tzee Ling Wong

and

Esther M. Hoffmann

submission deadline 20 Jul 2026 | 6 articles | Viewed by 6514 | Submission Open

Keywords: glaucoma; filtration surgery; trabeculectomy; MIGS; scarring; anti-metabolites; wound healing; anti-fibrotics

(This special issue belongs to the Section Ophthalmology)

Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition

edited by Jaime A. Hernández-Montfort

submission deadline 20 Jul 2026 | 3 articles | Viewed by 6230 | Submission Open

Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement

(This special issue belongs to the Section Cardiology)

Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis

edited by

Małgorzata Sobiecka

and

Monika Szturmowicz

submission deadline 20 Jul 2026 | 3 articles | Viewed by 5822 | Submission Open

Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines

(This special issue belongs to the Section Respiratory Medicine)

Chronic Kidney Disease: Current Challenges and Adverse Outcomes

edited by

Diana Tania Luminița Moldovan

and Flaviu Bob

submission deadline 20 Jul 2026 | 6 articles | Viewed by 5599 | Submission Open

Keywords: chronic kidney disease; CKD progression; hemodialysis; cardiovascular complications; vascular calcification; lifestyle; nutrition; bone and mineral disorders; CKD-associated osteoporosis; mortality

(This special issue belongs to the Section Nephrology & Urology)

Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives

edited by

Do-youn Lee

and

Myoung-Kwon Kim

submission deadline 20 Jul 2026 | 2 articles | Viewed by 5590 | Submission Open

Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine

(This special issue belongs to the Section Clinical Rehabilitation)

New Advances in Hip and Knee Arthroplasty

edited by Jun-Dong Chang

submission deadline 20 Jul 2026 | 7 articles | Viewed by 5476 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; revision surgery; orthopedic implants; robotic surgery; peri-operative care; functional outcomes; complication management; orthopedic innovation

(This special issue belongs to the Section Orthopedics)

Artificial Intelligence (AI) in Dental Clinical Practice

edited by

Eiji Tanaka

and Keiichiro Watanabe

submission deadline 20 Jul 2026 | 4 articles | Viewed by 5273 | Submission Open

Keywords: artificial intelligence; dental diagnostics; machine learning; deep learning; digital dentistry; clinical decision support; diagnostic automation; data transparency; evidence-based dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention

edited by Marco Ciardetti and Alessio Mattesini

submission deadline 20 Jul 2026 | 2 articles | Viewed by 4924 | Submission Open

Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification

(This special issue belongs to the Section Cardiology)

Broadening the Knowledge of Autism Spectrum Disorder in Adulthood: Advances in Diagnosis, Assessment and Treatment

edited by

Camilla Gesi

submission deadline 20 Jul 2026 | 1 articles | Viewed by 4427 | Submission Open

Keywords: autism spectrum disorder; adulthood; autism; comorbidity; gender; age-adjusted

(This special issue belongs to the Section Mental Health)

From Dual Diagnosis to Dual Disorder(s): Bridging Comorbidity and Integrated Clinical Understanding

edited by

Angelo G. I. Maremmani

submission deadline 20 Jul 2026 | 4 articles | Viewed by 4320 | Submission Open

Keywords: dual diagnosis; dual disorder; psychiatric comorbidity; addiction; integrated care; self-medication; substance use; mental illness; treatment models

(This special issue belongs to the Section Mental Health)

Atrial Fibrillation and Heart Failure: Diagnostic and Therapeutic Challenges and Breakthroughs

edited by

Silvius Alexandru Pescariu

Felix Bratosin

and

Cristian Mornos

submission deadline 20 Jul 2026 | 2 articles | Viewed by 3871 | Submission Open

Keywords: atrial fibrillation; heart failure; cardiac electrophysiology; ventricular remodelling; rhythm control; catheter abla-tion; neurohormonal activation; biomarkers; ischemia; integrated cardiovascular care

(This special issue belongs to the Section Cardiology)

Obesity-Related Metabolic and Cardiovascular Disorders

edited by

Lucia Frittitta

and Federica Vinciguerra

submission deadline 20 Jul 2026 | 4 articles | Viewed by 3545 | Submission Open

Keywords: obesity; type 2 diabetes mellitus; insulin resistance; metabolic syndrome; cardiovascular disease; lipid disorder; adipose tissue dysfunction; visceral adiposity; cardiometabolic risk; endothelial dysfunction; health disparities; gut microbiota; bariatric surgery; precision medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in the Management of Chronic Cough and Severe Asthma

edited by Ebymar Arismendi

submission deadline 20 Jul 2026 | 2 articles | Viewed by 3534 | Submission Open

Keywords: asthma; chronic cough; biomarkers; exacerbations; biologics; precision medicine; airway inflammation; pediatric asthma

(This special issue belongs to the Section Respiratory Medicine)

Aortic Valve Disease: Current Evolution and Future Opportunities

edited by Gianluigi Perri

submission deadline 20 Jul 2026 | 4 articles | Viewed by 3534 | Submission Open

Keywords: aortic valve disease; aortic valve repair; Ross procedure; aortic valve replacement; diagnosis of aortic valve disease

(This special issue belongs to the Section Cardiology)

Insights on Cancer Diagnosis, Treatment and Side Effects Management

edited by

Octav Ginghină

Mihai-Teodor Georgescu

and

Laurentia Nicoleta Gales

submission deadline 20 Jul 2026 | 3 articles | Viewed by 3474 | Submission Open

Keywords: cancer diagnosis; cancer treatment; side effects management; oncology; personalized medicine; supportive care

(This special issue belongs to the Section Oncology)

Advances in Hepatitis: Prevention, Treatment, and Global Health Impact

edited by

Michał Brzdęk

Dorota Zarębska-Michaluk

and

Krystyna Dobrowolska

submission deadline 20 Jul 2026 | 4 articles | Viewed by 3399 | Submission Open

Keywords: hepatitis B; hepatitis C; liver disease; direct-acting antivirals (DAAs); global health; public health policy; viral hepa-titis elimination; health disparities; cirrhosis; vaccination programs

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis

edited by

Roberto Carbone

submission deadline 20 Jul 2026 | 2 articles | Viewed by 3394 | Submission Open

Keywords: pulmonary hypertension; interstitial lung disease; idiopathic pulmonary fibrosis; heart failure; mitral valve disease

(This special issue belongs to the Section Respiratory Medicine)

Ocular Surface Disease: Epidemiology, Diagnosis and Management

edited by

Sandeep K. Dhallu

and

Nicole Carnt

submission deadline 20 Jul 2026 | 3 articles | Viewed by 3386 | Submission Open

Keywords: dry eye disease; risk factors; ocular surface disease; inflammatory biomarkers; anterior segment imaging; emerging therapies

(This special issue belongs to the Section Ophthalmology)

Innovations in Interventional Cardiology: Advancing Minimally Invasive Cardiac Care

edited by

Konstantinos Stathogiannis

submission deadline 20 Jul 2026 | 3 articles | Viewed by 3382 | Submission Open

Keywords: TAVI; TAVR; MTEER; TTEER; TTVR; ASD; PFO; IVUS; OCT

(This special issue belongs to the Section Cardiology)

Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition)

edited by

Carlo Barausse

and

Gerardo Pellegrino

submission deadline 20 Jul 2026 | 2 articles | Viewed by 3297 | Submission Open

Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Challenges and Advances in Periodontology and Oral Surgery: 2nd Edition

edited by

Glauco Chisci

submission deadline 20 Jul 2026 | 3 articles | Viewed by 3187 | Submission Open

Keywords: oral surgery; third molar; periodontitis; antibiotics; infection; pain; research; advances; complications; dental implants; bone regeneration; maxillofacial surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications

edited by

Petroula N. Nana

, Tilo Kölbel and José Ignacio F. Torrealba

submission deadline 20 Jul 2026 | 6 articles | Viewed by 3150 | Submission Open

Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes

(This special issue belongs to the Section Vascular Medicine)

Paradigms, Advances and Future Directions in Oral Medicine

edited by

Pia Lopez-Jornet

submission deadline 20 Jul 2026 | 4 articles | Viewed by 3096 | Submission Open

Keywords: oral medicine; oral potentially malignant disorders; leukoplakia; oral lichen planus; orofacial pain; biopsy and liquid biopsy; biomarkers

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 251-300 on page 6 of 31.

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