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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Management of Atherosclerosis

edited by Luca Di Vito

submission deadline 28 Feb 2025 | 2 articles | Viewed by 3142 | Submission Open

Keywords: plaque erosion; plaque rupture; myocardial strain; coronary computed tomography angiography; MINOCA; recurrent coronary events; PCSK9 inhibitors; inclisiran; microvascular dysfunction

(This special issue belongs to the Section Cardiology)

Chronic Obstructive Pulmonary Disease (COPD): Treatment and Management

edited by Maurizio Marvisi and Alfredo Chetta

submission deadline 28 Feb 2025 | 2 articles | Viewed by 2046 | Submission Open

Keywords: COPD; treatable traits; precision medicine; COPD comorbidities; COPD mortality

(This special issue belongs to the Section Pulmonology)

Recent Developments in Transcatheter Aortic Valve Implantation

edited by

Edward James Frazer Danson

submission deadline 28 Feb 2025 | 2 articles | Viewed by 1625 | Submission Open

Keywords: transcatheter aortic valve implantation; TAVI; aortic valve stenosis; interventional cardiac surgery; heart valve disease

(This special issue belongs to the Section Cardiovascular Medicine)

Cerebrovascular Disease: Symptoms, Diagnosis and Current Treatment

edited by Alba Scerrati and Giorgio Mantovani

submission deadline 28 Feb 2025 | 1 articles | Viewed by 1452 | Submission Open

Keywords: ischemic stroke; cerebral aneurysms; cerebral vascular malformation; cerebral venous disease; cerebral venous thrombosis

(This special issue belongs to the Section Clinical Neurology)

Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment

edited by

Rubén Cuesta-Barriuso

submission deadline 28 Feb 2025 | 3 articles | Viewed by 1299 | Submission Open

Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment

(This special issue belongs to the Section Clinical Rehabilitation)

Challenges in the Field of Psycho-Oncology: Insights from Research

edited by

Ana Bartolo

Sara Monteiro

, Tânia Brandão and Ricardo Teixeira

submission deadline 28 Feb 2025 | 1 articles | Viewed by 1158 | Submission Open

Keywords: cancer; psycho-oncology; survivorship care; psychological distress; quality of life; sustainable development goals; global health; health disparities

(This special issue belongs to the Section Oncology)

Advances in the Prevention, Management, and Rehabilitation of Sports Injuries

edited by

Mutsuaki Edama

submission deadline 28 Feb 2025 | 1 articles | Viewed by 1007 | Submission Open

Keywords: prevention; rehabilitation; physical therapy; clinical anatomy; exercise; ultrasonography; foot and ankle; tendon; musculoskeletal; female athlete

(This special issue belongs to the Section Sports Medicine)

Recent Advances in Neurorehabilitation: Emerging Techniques and Technologies

edited by

Serena Dattola

and

Lilla Bonanno

submission deadline 28 Feb 2025 | 1 articles | Viewed by 737 | Submission Open

Keywords: neurorehabilitation; neuroimaging; robotic rehabilitation; virtual reality therapy; neuroprosthetics; brain– computer interfaces; pharmacological interventions; functional recovery; neuroplasticity; cognitive rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Clinical Perspectives on Adenomyosis- and Endometriosis-Associated Infertility

edited by Dimitrios Rafail Kalaitzopoulos and Angelos Daniilidis

submission deadline 28 Feb 2025 | 1 articles | Viewed by 728 | Submission Open

Keywords: endometriosis; adenomyosis; infertility; assisted reproductive technology; IVF; laparoscopy; hormonal therapy; reproductive outcomes

(This special issue belongs to the Section Obstetrics & Gynecology)

Manual Therapy for the Prevention and Management of Musculoskeletal and Related Disorders across the Life Course

edited by

Christian Lunghi

and

Federica Tamburella

submission deadline 28 Feb 2025 | Viewed by 405 | Submission Open

Keywords: physiotherapy; osteopathy; chiropractic; functional restoration; pain management; biopsychosocial model; psychoneuroim-munology; person-centered care; manual therapy interventions

(This special issue belongs to the Section Orthopedics)

New Insights into Glaucoma

edited by

Su-Ho Lim

and Daniel Laroche

submission deadline 28 Feb 2025 | Viewed by 324 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)

(This special issue belongs to the Section Ophthalmology)

Endocrine Surgery: Current Developments and Trends

edited by Leonardo Rossi and Gabriele Materazzi

submission deadline 28 Feb 2025 | Viewed by 183 | Submission Open

Keywords: thyroid; parathyroid; adrenal gland; minimally invasive surgery; remote-access surgery; robotic surgery; parathyroid fluorescence; adrenal fluorescence

(This special issue belongs to the Section Endocrinology & Metabolism)

Updates on Interstitial Lung Disease

edited by

Atul C. Mehta

and Sameep Sehgal

submission deadline 28 Feb 2025 | Viewed by 158 | Submission Open

Keywords: interstitial lung disease; idiopathic pulmonary fibrosis; lung transplantation; connective tissue disease; bronchoscopy

(This special issue belongs to the Section Pulmonology)

Challenges and Opportunities in Cardiac Anesthesiology

edited by

Henning Hermanns

and Ragnar Huhn

submission deadline 28 Feb 2025 | Viewed by 126 | Submission Open

Keywords: cardiac surgery; perioperative monitoring; hemodynamic management; anesthetic agents; enhanced recovery; minimally invasive surgery; robotic-assisted surgery; patient outcomes; anesthesia techniques; pharmacological innovations

(This special issue belongs to the Section Anesthesiology)

Physical Activity, Exercise, and Health: Bridging Research and Clinical Practice

edited by

Hannah Moir

submission deadline 28 Feb 2025 | Viewed by 112 | Submission Open

Keywords: physical activity; exercise; health; disease prevention; clinical practice; exercise physiology; exercise prescription; rehabilitation; chronic diseases

(This special issue belongs to the Section Sports Medicine)

New Approaches in Intravenous Anesthesia and Anesthetics—Part IV

edited by

Keira P. Mason

submission deadline 28 Feb 2025 | Viewed by 112 | Submission Open

Keywords: sedation; safety; intravenous; target-controlled infusions; adverse events; future; regional anesthesia

(This special issue belongs to the Section Anesthesiology)

Updates in the Orthopedic Management of Foot Disorders: 2nd Edition

edited by

Carlo Biz

and

Pietro Ruggieri

submission deadline 28 Feb 2025 | Viewed by 101 | Submission Open

Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Diagnosis and Treatment of Myocardial Infarction

edited by

Clara Bonanad

submission deadline 28 Feb 2025 | Viewed by 98 | Submission Open

Keywords: myocardial infarction; ischemic heart disease; coronary artery disease; coronary syndrome; atherosclerosis

(This special issue belongs to the Section Cardiology)

Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

edited by Ahmed Abuzaid

submission deadline 28 Feb 2025 | Viewed by 93 | Submission Open

Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations

(This special issue belongs to the Section Cardiology)

Updates on Brain Tumors: Diagnosis and Treatment

edited by Jigisha P. Thakkar and

Rimas V Lukas

submission deadline 28 Feb 2025 | Viewed by 93 | Submission Open

Keywords: primary brain tumors; glioblastoma; IDH mutant glioma; meningioma; brain metastases; leptomeningeal disease

(This special issue belongs to the Section Clinical Neurology)

New Trends in Minimally Invasive Thoracic Surgery

edited by Maria Letizia Vita, Leonardo Petracca Ciavarella and Alberto Biondi

submission deadline 28 Feb 2025 | Viewed by 84 | Submission Open

Keywords: thoracic surgery; minimally invasive surgery; VATS; awake surgery; esophageal cancer

(This special issue belongs to the Section General Surgery)

Non-Small-Cell Lung Cancer: Screening, Diagnosis and Treatment Options in the AI and Omics Era

edited by Miljana Tanić

submission deadline 28 Feb 2025 | Viewed by 82 | Submission Open

Keywords: lung cancer; NSCLC; radiomics; digital pathology; electronic health records; tumor profiling; AI; machine learning; deep learning; liquid biopsy; early detection; diagnosis; prognosis; therapy; biomarkers; management

(This special issue belongs to the Section Pulmonology)

Advancements in Cardiac Electrophysiology through Biomedical Engineering for Abnormality Monitoring and Detection in Clinical Practice

edited by Ilaria Marcantoni and Michela Casella

submission deadline 28 Feb 2025 | Viewed by 82 | Submission Open

Keywords: electrocardiogram; cardiac electrophysiology; cardiac risk index; cardiac arrhythmias; electrocardiographic alternans; long QT syndrome; heart electrical system anomalies; monitoring of heart electrical system; prevention; biomedical engineering in electrocardiology; cardiac signal processing; cardiac image processing

(This special issue belongs to the Section Cardiology)

Clinical Implications of Neuroglia in the Development of Neurological Disorders

edited by Clarissa Fantin Cavarsan

submission deadline 28 Feb 2025 | Viewed by 75 | Submission Open

Keywords: neuroglia cells; clinical implications; neurological disorders; neuroinflammation; neurodegeneration; neuroregen-eration; therapeutic targets; disease progression

(This special issue belongs to the Section Clinical Neurology)

Targeted Treatment in Chronic Inflammatory Arthritis

edited by

Cinzia Rotondo

Simone Parisi

and Simone Perniola

submission deadline 28 Feb 2025 | Viewed by 63 | Submission Open

Keywords: rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis; spondyloarthritis; disease-modifying antirheumatic drugs (DMARDs); personalized medicine; immunomodulatory therapies; patient outcomes; combination therapies

(This special issue belongs to the Section Immunology)

New Diagnostic and Therapeutic Trends in Sepsis and Septic Shock

edited by Christian Zanza,

Luigi La Via

Antonio Voza

and

Yaroslava Longhitano

submission deadline 28 Feb 2025 | Viewed by 63 | Submission Open

Keywords: sepsis; septic shock; diagnostics; therapeutics; biomarkers; critical care

(This special issue belongs to the Section Hematology)

Pediatric Critical Care: Clinical Recognition, Management, and Outcomes

edited by Janet Hume

submission deadline 28 Feb 2025 | Viewed by 60 | Submission Open

Keywords: pediatric critical care medicine; sepsis; pediatric acute respiratory distress syndrome; mechanical ventilation; renal replacement therapy; chronic critical illness; post-intensive care syndrome

(This special issue belongs to the Section Clinical Pediatrics)

Orthopedic Surgery: Recent Advances and Prospects

edited by Mitchell K. Ng

submission deadline 28 Feb 2025 | Viewed by 58 | Submission Open

Keywords: orthopedic surgery; clinical updates; joint reconstruction; spine surgery; trauma; elective surgery; peri-operative management

(This special issue belongs to the Section Orthopedics)

New Advances in Keratoplasty

edited by Cristina Bovone

submission deadline 28 Feb 2025 | Viewed by 58 | Submission Open

Keywords: lamellar keratoplasty; descemet stripping endothelial keratoplasty (DSAEK); descemet membrane endothelial keratoplasty (DMEK); deep anterior lamellar keratoplasty (DALK); keratoconus; corneal dystrophies; bullous keratopathy; anterior segment OCT

(This special issue belongs to the Section Ophthalmology)

Cutting Edge of Minimally Invasive Spine Surgery

edited by

Yoshihisa Kotani

submission deadline 28 Feb 2025 | Viewed by 57 | Submission Open

Keywords: spine surgery; minimally invasive surgery; spinal deformity; spine fusion; enabling technology; spinal navigation; robotic surgery; spine materials; spinal endoscopy

(This special issue belongs to the Section Orthopedics)

Perioperative Management and Outcome of General and Abdominal Surgery

edited by

Valeriu Surlin

submission deadline 28 Feb 2025 | Viewed by 56 | Submission Open

Keywords: perioperative management; enhanced recovery after surgery; postoperative recovery; preoperative preparation; surgical outcome

(This special issue belongs to the Section General Surgery)

Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)

edited by

Pierluigi Carratù

submission deadline 28 Feb 2025 | Viewed by 54 | Submission Open

Keywords: obstructive sleep apnea syndrome; diagnosis; obesity; treatment; CPAP; comorbidities; cardiovascular risk

(This special issue belongs to the Section Pulmonology)

Blood Disorders: Diagnosis, Management, and Future Opportunities

edited by

Cristina Panuzzo

and

Barbara Pergolizzi

submission deadline 28 Feb 2025 | Viewed by 54 | Submission Open

Keywords: blood disorders; biomarkers; personalized medicine; diagnosis; NGS; metabolomics; digital droplet PCR (ddPCR)

(This special issue belongs to the Section Hematology)

Advances in Diagnosis and Treatment of Thyroid Disorders

edited by

Eleonora Lori

Salvatore Ulisse

and

Salvatore Sorrenti

submission deadline 28 Feb 2025 | Viewed by 50 | Submission Open

Keywords: thyroid surgery; targeted therapy; goiter; papillary thyroid cancer; medullary thyroid cancer; artificial intelligence; ultrasound imaging; minimally invasive approach; remote access; molecular biomarkers

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Progress of Mastectomy and Breast Reconstruction Surgery

edited by Antoine L. Carre and Mouchammed Agko

submission deadline 28 Feb 2025 | Viewed by 48 | Submission Open

Keywords: autologous breast reconstruction; reinnervation; mastectomy; robotic DIEP (deep inferior epigastric perforator) flap; rib-sparing DIEP flap; neurotization of DIEP flap; nipple-sparing neurotization; nipple-sparing mastectomy of large breasts; hematoma after mastectomy; robotic mastectomy; pre-pectoral alloplastic reconstruction

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Research Trends and Applications of Hematopoietic Stem Cell Transplantation

edited by David C. Shyr and Robertson Parkman

submission deadline 28 Feb 2025 | Viewed by 46 | Submission Open

Keywords: hematopoietic stem cell transplant; conditioning regimen; immunology; graft-versus-host disease; gene therapy; transplant-related toxicities; alternative donor stem cell transplant; supportive care

(This special issue belongs to the Section Hematology)

Current and Emerging Treatment Options in Skull Base Surgery and Neuro-Oncology

edited by Antonio Meola and Leonello Tacconi

submission deadline 28 Feb 2025 | Viewed by 46 | Submission Open

Keywords: skull base; neuro-oncology; brain tumor; artificial intelligence; radiosurgery; targeted therapy; neuro endoscopy

(This special issue belongs to the Section Clinical Neurology)

High-Flow Nasal Cannula (HFNC) and Noninvasive Ventilation: What Is New in Acute, Chronic and Rehabilitation Settings?

edited by

Paola Pierucci

and

Anna Annunziata

submission deadline 28 Feb 2025 | Viewed by 43 | Submission Open

Keywords: NIV; HFNC; noninvasive ventilation; acute respiratory insufficiency; chronic respiratory insufficiency

(This special issue belongs to the Section Pulmonology)

Eosinophilic Esophagitis: Clinical Advances in Diagnosis, Treatment, and Monitoring

edited by Pierfrancesco Visaggi, Edoardo Vincenzo Savarino and

Nicola De Bortoli

submission deadline 28 Feb 2025 | Viewed by 41 | Submission Open

Keywords: eosinophilic esophagitis (EoE); diagnosis ; treatment ; monitoring; disease assessment; precision medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Severe Infection and Antimicrobial Management in ICU

edited by Ming Chen

submission deadline 28 Feb 2025 | Viewed by 40 | Submission Open

Keywords: early diagnosis of bacteremia in ICUs; rational antibiotic treatment of bacteremia in ICUs; relationship between early diagnosis and antimicrobial management in ICUs

(This special issue belongs to the Section Infectious Diseases)

Autoimmunity—Affecting Different Organ Systems (from Guts to Brain)

edited by

Markus C. Kowarik

and Sebastian Saur

submission deadline 28 Feb 2025 | Viewed by 39 | Submission Open

Keywords: autoimmune diseases; inflammatory bowl diseases; rheumatological diseases; neuro-inflammatory diseases; immunosuppression; overlap syndromes; treatment options for autoimmune diseases

(This special issue belongs to the Section Immunology)

Clinical Advances in Valvular Heart Diseases

edited by

Mohammad Kassar

submission deadline 5 Mar 2025 | Viewed by 49 | Submission Open

Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis

(This special issue belongs to the Section Cardiology)

Clinical Perspectives on Cardiac Electrophysiology and Arrhythmias

edited by Constantin T. Luca and

Simina Crisan

submission deadline 8 Mar 2025 | 2 articles | Viewed by 748 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; cardiac pacing; implantable cardioverter-defibrillators; cardiac resynchronization therapy; catheter ablation; arrhythmogenic disorders; cardiomyopathy; electrical storm; heart failure

(This special issue belongs to the Section Cardiovascular Medicine)

Adverse Pregnancy Outcomes: Current Status, Challenges and Future Directions

edited by

Demetra Socolov

, Iuliana Ceausu and Elena Bernad

submission deadline 10 Mar 2025 | Viewed by 55 | Submission Open

Keywords: great obstetrical syndromes; adverse pregnancy outcomes; screening; prediction; prophylaxis; diagnosis; long-term follow-up; perinatal management; intrapartum management

(This special issue belongs to the Section Obstetrics & Gynecology)

Chronic Coronary Artery Disease: New Treatments and Future Directions

edited by

Ioannis Vogiatzis

submission deadline 12 Mar 2025 | Viewed by 42 | Submission Open

Keywords: risk assessment; coronary atherosclerosis; platelet disorders; lipid reduction; angina; percutaneous coronary intervention (PCI); coronary artery bypass grafting (CABG); patient recovery and rehabilitation; smoking; second-hand smoke and e-cigarettes cessation

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Updates and Perspectives of Implant Dentistry

edited by

Renzo Guarnieri

and

Rodolfo Reda

submission deadline 13 Mar 2025 | Viewed by 35 | Submission Open

Keywords: osseointegration; soft tissue integration; peri-implant diseases

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Trends in Vascular and Endovascular Surgery

edited by Karin Pfister and Fiona Rohlffs

submission deadline 15 Mar 2025 | 7 articles | Viewed by 6177 | Submission Open

Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept

(This special issue belongs to the Section Vascular Medicine)

Emerging Technologies for Dental Imaging

edited by

Egon Burian

submission deadline 15 Mar 2025 | 2 articles | Viewed by 1777 | Submission Open

Keywords: dental imaging; dental MRI; caries; periodontitis; orthodontics; oral surgery; craniomaxillofacial surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiomyopathies: Current Treatment and Future Options: Second Edition

edited by

Stefan Peters

submission deadline 15 Mar 2025 | Viewed by 71 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; restrictive cardiomyopathy; amyloid cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy

(This special issue belongs to the Section Cardiology)

New Trends in the Management of Periodontitis and Peri-Implantitis

edited by

João Botelho

submission deadline 15 Mar 2025 | Viewed by 33 | Submission Open

Keywords: periodontitis; periodontal disease; peri-implantitis; regenerative therapies; diagnostic markers; biomaterials; personalized medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 1051-1100 on page 22 of 25.

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