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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Application of Echocardiography in the Diagnosis of Cardiovascular Diseases
edited by Francesco Melillo
submission deadline 25 Feb 2025 | 1 articles | Viewed by 1431 | Submission Open
Keywords: echocardiography; 3D-echo; speckle tracking; diagnosis; subclinical myocardial disease
(This special issue belongs to the Section Cardiology)
Sleep in Neurology—Sleep Disorders and Dysfunction of the Nervous System
edited by
submission deadline 25 Feb 2025 | 1 articles | Viewed by 904 | Submission Open
Keywords: sleep; neurology; insomnia; restless leg syndrome; REM sleep behavior disorder; parasomnia; somnambulism; neurodegenerative disorders; brain injury; sleep-related movement disorders
(This special issue belongs to the Section Clinical Neurology)
Clinical Challenges in Heart Failure Management
edited by Paolo Severino and Gaetano M. Ruocco
submission deadline 25 Feb 2025 | 1 articles | Viewed by 704 | Submission Open
Keywords: acute heart failure; chronic heart failure; inotropic support; left ventricular assist device; cardiac contractility modulation; guanylate cyclase stimulators; quality of life; telemedicine; palliative care
(This special issue belongs to the Section Cardiology)
Orthopedic Trauma and Fracture Care: Patient Expectations and Fulfillment in Clinical Practice
edited by Tim Saier
submission deadline 25 Feb 2025 | 1 articles | Viewed by 515 | Submission Open
Keywords: fracture; trauma surgery; patient-reported outcome; expectation; fulfillment
(This special issue belongs to the Section Orthopedics)
Juvenile Idiopathic Arthritis (JIA): Diagnosis, Treatment and Latest Updates
edited by
submission deadline 25 Feb 2025 | 1 articles | Viewed by 509 | Submission Open
Keywords: juvenile idiopathic arthritis; pathophysiology; genetic predisposition; immunologic abnormalities; diagnosis; treatment; outcome
(This special issue belongs to the Section Clinical Pediatrics)
New Directions for Treatment and Assessment of Ulcerative Colitis submission deadline 25 Feb 2025 | 1 articles | Viewed by 484 | Submission Open
Keywords: treatment; ulcerative colitis; treatment target; ultrasound assessment; approach
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Insights into Joint Arthroplasty
edited by
submission deadline 25 Feb 2025 | 1 articles | Viewed by 480 | Submission Open
Keywords: total hip arthroplasty; total knee arthroplasty; robotic-assisted technology and navigation; modern implant materials; modern implant fixation techniques; alignment in TKA; spinopelvic alignment in THA
(This special issue belongs to the Section Orthopedics)
The Intersection of Diabetes and Heart Diseases: Advances in Science and Management
edited by Krishnaswami Vijayaraghavan
submission deadline 25 Feb 2025 | Viewed by 315 | Submission Open
Keywords: type 2 diabetes; heart failure; hypertension; heart disease
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Treatment and Management of Pulmonary Arterial Hypertension
edited by , Megan Griffiths and Michael Risbano
submission deadline 25 Feb 2025 | Viewed by 289 | Submission Open
Keywords: pulmonary arterial hypertension; pulmonary hypertension; pulmonary vascular remodeling; right ventricle; right ventricular– pulmonary artery uncoupling; six-minute walk distance
(This special issue belongs to the Section Cardiovascular Medicine)
New Clinical Insights into Exercise, Obesity, and Diabetes
edited by , , Ana Conceição and
submission deadline 25 Feb 2025 | Viewed by 251 | Submission Open
Keywords: diabetes; obesity; physical activity; exercise prescription; physically active learning; tissue oxidation; exercise physiology; physically active senior centres
(This special issue belongs to the Section Sports Medicine)
Robotic Urological Surgery: Clinical Updates for Better Outcomes
edited by
submission deadline 25 Feb 2025 | Viewed by 250 | Submission Open
Keywords: robotic urological surgery; clinical outcomes; surgical techniques; surgical navigation; patient-reported outcomes; side effects; incident
(This special issue belongs to the Section Nephrology & Urology)
New Challenges in Psoriasis Management
edited by Mario Valenti
submission deadline 25 Feb 2025 | Viewed by 232 | Submission Open
Keywords: psoriasis; psoriatic arthritis; biologics; small molecules; immune-mediated skin diseases
(This special issue belongs to the Section Dermatology)
New Advances in Total Knee Arthroplasty
edited by
submission deadline 25 Feb 2025 | Viewed by 209 | Submission Open
Keywords: artificial intelligence; bone tumors; knee joint; knee pain; knee replacement; knee surgery; orthopedic surgery; osteoarthritis; prognostic markers; radiological evaluation
(This special issue belongs to the Section Orthopedics)
Interventional Pulmonology: Advances and Future Directions
edited by Martina Ferioli and Piero Candoli
submission deadline 25 Feb 2025 | Viewed by 191 | Submission Open
Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging
(This special issue belongs to the Section Pulmonology)
Parkinson's Disease: Diagnosis, Treatment, and Management
edited by
submission deadline 25 Feb 2025 | Viewed by 188 | Submission Open
Keywords: Parkinson’ s; early diagnosis of Parkinson’ s; therapeutics; molecular interventions
(This special issue belongs to the Section Clinical Neurology)
Updates on Rheumatoid Arthritis: From Diagnosis to Treatment
edited by
submission deadline 25 Feb 2025 | Viewed by 187 | Submission Open
Keywords: rheumatoid arthritis; pharmacological intervention; treatment; clinical development; effectiveness; safety; immune therapy; biological disease-modifying antirheumatic drugs (bDMARDs); synthetic disease-modifying antirheumatic drugs (sDMARDs)
(This special issue belongs to the Section Immunology)
Thrombosis: Latest Advances and Prospects
edited by Manila Gaddh
submission deadline 25 Feb 2025 | Viewed by 173 | Submission Open
Keywords: thromboembolism; venous thrombosis; arterial thrombosis; anticoagulation
(This special issue belongs to the Section Hematology)
Psoriasis and Psoriatic Arthritis: How to Treat in the Era of Biologics and Small Molecule Inhibitors: 3rd Edition submission deadline 25 Feb 2025 | Viewed by 160 | Submission Open
Keywords: psoriasis; psoriatic arthritis; biologics; small molecule inhibitors; conventional therapies
(This special issue belongs to the Section Dermatology)
Clinical Diagnostics and Treatment of Macular Degeneration
edited by Moreno Menghini and
submission deadline 25 Feb 2025 | Viewed by 159 | Submission Open
Keywords: age-related macular degeneration; AMD; geographic atrophy; optical coherence tomography; OCT; artificial intelligence; AI; anti-VEGF; anti-ANG2; complement inhibition
(This special issue belongs to the Section Ophthalmology)
New Clinical Insights into Aortic Surgery
edited by Rainald Seitelberger and Andreas Vötsch
submission deadline 25 Feb 2025 | Viewed by 139 | Submission Open
Keywords: aortic organ; aortic aneurysm; aortic syndrome; aortic dissection; frozen elephant trunk; TEVAR; aortic center
(This special issue belongs to the Section Cardiology)
Personalized Treatment Modalities for Rectal Cancer
edited by Christy E. Cauley and Srinivas Joga Ivatury
submission deadline 25 Feb 2025 | Viewed by 137 | Submission Open
Keywords: rectal cancer; decision support; sphincter-sparing surgery; early onset colorectal cancer; pelvic radiation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Orthopedic Trauma Surgery: Current Challenges and Future Perspectives
edited by Paolo Schiavi, Enrico Vaienti and Francesco Pogliacomi
submission deadline 26 Feb 2025 | Viewed by 308 | Submission Open
Keywords: trauma surgery; politrauma; osteosynthesis; arthroplasty; internal fixation; MIPO; outcome
(This special issue belongs to the Section Orthopedics)
Sepsis: New Insights into Diagnosis and Treatment
edited by and Etrusca Brogi
submission deadline 27 Feb 2025 | Viewed by 238 | Submission Open
Keywords: sepsis and sepsis subphenotypes; adjuvant therapy; blood purification strategies; immunomonitoring and immunotherapy; the microbiome in sepsis; crosstalk in multi-organ failure (MOF); ultrasound in sepsis (POCUS); sepsis-induced coagulophaty and DIC; antibiotic therapy; multimodal approaches to surgical source control
(This special issue belongs to the Section Infectious Diseases)
Clinical Diagnostics and Therapeutics Advances in Acute and Chronic Heart Failure
edited by Ilaria Battistoni and Emilia D'Elia
submission deadline 27 Feb 2025 | Viewed by 141 | Submission Open
Keywords: acute heart failure; chronic heart failure; gray zones; SGLT2i; cardiogenic shock; cardiopulmonary test; vericiguat; worsening heart failure; advanced heart failure; biomarkers; palliative care
(This special issue belongs to the Section Cardiology)
Sports Exercise: How It Benefits Health and Disease submission deadline 28 Feb 2025 | 17 articles | Viewed by 26414 | Submission Open
Keywords: metabolic disease; muscle; high-intensity interval training; strength training; sports exercise
(This special issue belongs to the Section Sports Medicine)
Advanced Research in Myopia and Other Visual Disorders submission deadline 28 Feb 2025 | 8 articles | Viewed by 19056 | Submission Open
Keywords: refractive errors; visual disorders; epidemiology; myopia; children; interventions; prevention; risk factors; ocular pathologies
(This special issue belongs to the Section Ophthalmology)
Modern Patient-Centered Dental Care
edited by Eitan Mijiritsky
submission deadline 28 Feb 2025 | 13 articles | Viewed by 18302 | Submission Open
Keywords: dental implants; digital dentistry; patient satisfaction; innovative clinical dental approaches
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Mechanical Circulatory Support in Patients with Heart Failure
edited by Arun K Singhal and Ernesto Ruiz Duque
submission deadline 28 Feb 2025 | 6 articles | Viewed by 14374 | Submission Open
Keywords: mechanical circulatory support; ECMO; impella; left ventricular assist device; heart failure; cardiogenic shock; microaxial support pump
(This special issue belongs to the Section Cardiology)
Knee Osteoarthritis: Clinical Updates and Perspectives
edited by and Shinnosuke Hada
submission deadline 28 Feb 2025 | 8 articles | Viewed by 12105 | Submission Open
Keywords: knee osteoarthritis; diagnosis; cell therapy; platelet-rich plasma; exosome; knee osteotomy; arthroplasty; physiotherapy; conservative treatment; surgical treatment
(This special issue belongs to the Section Orthopedics)
Kidney Failure: Diagnosis and Treatment of Acute and Chronic Conditions
edited by Nikolina Basic-Jukic
submission deadline 28 Feb 2025 | 8 articles | Viewed by 10549 | Submission Open
Keywords: kidney failure; renal dysfunction; hyponatremia; peritoneal dialysis; hemodialysis; renal transplantation; immunoadsorption; plasma exchange
(This special issue belongs to the Section Nephrology & Urology)
Management of Atherosclerosis
edited by Luca Di Vito
submission deadline 28 Feb 2025 | 4 articles | Viewed by 8782 | Submission Open
Keywords: plaque erosion; plaque rupture; myocardial strain; coronary computed tomography angiography; MINOCA; recurrent coronary events; PCSK9 inhibitors; inclisiran; microvascular dysfunction
(This special issue belongs to the Section Cardiology)
Advances in the Clinical Management of Perioperative Anesthesia
edited by Alessia Mattei, Rita Cataldo and
submission deadline 28 Feb 2025 | 7 articles | Viewed by 8376 | Submission Open
Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit
(This special issue belongs to the Section Anesthesiology)
Acute Ischemic Stroke: Current Status and Future Challenges
edited by
submission deadline 28 Feb 2025 | 6 articles | Viewed by 7634 | Submission Open
Keywords: acute ischemic stroke; atrial fibrillation; endovascular thrombectomy; intravenous thrombolysis; direct oral anticoagulants
(This special issue belongs to the Section Clinical Neurology)
Gastrointestinal Cancer: Outcomes and Therapeutic Management
edited by Maximos Frountzas
submission deadline 28 Feb 2025 | 6 articles | Viewed by 7431 | Submission Open
Keywords: surgical oncology; gastrointestinal cancer; esophageal; gastric; hepatic; biliary; pancreatic; colon; rectal; neoplasm
(This special issue belongs to the Section Oncology)
New and Emerging Concepts in Cardiometabolic Risk Factors and Cognitive Disorders
edited by and Ihab M. Hajjar
submission deadline 28 Feb 2025 | 4 articles | Viewed by 6842 | Submission Open
Keywords: Alzheimer’ s disease; cognition; dementia; hypertension; older adults
(This special issue belongs to the Section Cardiology)
Clinical Management of Pregnancy-Related Complications—Part II
edited by , Stephanos Zervoudis and
submission deadline 28 Feb 2025 | 3 articles | Viewed by 5187 | Submission Open
Keywords: diabetes; hypertension; post-partum hemorrhage; preterm labor; infection; cancer
(This special issue belongs to the Section Obstetrics & Gynecology)
Manual Therapy for the Prevention and Management of Musculoskeletal and Related Disorders across the Life Course submission deadline 28 Feb 2025 | 3 articles | Viewed by 5009 | Submission Open
Keywords: physiotherapy; osteopathy; chiropractic; functional restoration; pain management; biopsychosocial model; psychoneuroim-munology; person-centered care; manual therapy interventions
(This special issue belongs to the Section Orthopedics)
Physical Activity, Exercise, and Health: Bridging Research and Clinical Practice
edited by
submission deadline 28 Feb 2025 | 4 articles | Viewed by 4999 | Submission Open
Keywords: physical activity; exercise; health; disease prevention; clinical practice; exercise physiology; exercise prescription; rehabilitation; chronic diseases
(This special issue belongs to the Section Sports Medicine)
Autoimmune Diseases and Cardiovascular System: Physiopathology, Epidemiology, Clinical Characteristics and Therapeutic Strategies
edited by Gian Luca Erre
submission deadline 28 Feb 2025 | 2 articles | Viewed by 4866 | Submission Open
Keywords: cardiovascular events; cardiovascular risk; atherosclerosis; autoimmune diseases; treatment
(This special issue belongs to the Section Immunology)
Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment submission deadline 28 Feb 2025 | 4 articles | Viewed by 4639 | Submission Open
Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment
(This special issue belongs to the Section Clinical Rehabilitation)
Diagnosing Pancreatic Cancer: Imaging Scan and Endoscopic Ultrasound
edited by , Ioannis Anastasiou and
submission deadline 28 Feb 2025 | 2 articles | Viewed by 4464 | Submission Open
Keywords: pancreatic cancer; endoscopic ultrasound (EUS); artificial intelligence; staging and biopsy (FNA / FNB); pancreatitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Clinical Advances in Pediatric Allergic Diseases
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 4393 | Submission Open
Keywords: allergic diseases; biomarkers; tailor treatment; allergen immunotherapy; biologics
(This special issue belongs to the Section Clinical Pediatrics)
Targeted Treatment in Head–Neck Cancer
edited by Jacopo Zocchi, Gerardo Petruzzi and
submission deadline 28 Feb 2025 | 3 articles | Viewed by 4307 | Submission Open
Keywords: head and neck squamous cell carcinoma; precision medicine; targeted therapies; immunotherapy; tumor heterogeneity; treatment response monitoring
(This special issue belongs to the Section Otolaryngology)
Clinical Perspectives on Adenomyosis- and Endometriosis-Associated Infertility
edited by Dimitrios Rafail Kalaitzopoulos and Angelos Daniilidis
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3717 | Submission Open
Keywords: endometriosis; adenomyosis; infertility; assisted reproductive technology; IVF; laparoscopy; hormonal therapy; reproductive outcomes
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Coronary Artery Disease
edited by and Jose M Montero-Cabezas
submission deadline 28 Feb 2025 | 4 articles | Viewed by 3630 | Submission Open
Keywords: coronary artery disease; acute coronary syndromes; chronic coronary syndromes; myocardial infarction with non-obstructive coronary artery disease; spontaneous coronary artery dissection; myocardial infarction; coronary physiology; multimodality imaging
(This special issue belongs to the Section Cardiology)
Recent Developments in Transcatheter Aortic Valve Implantation submission deadline 28 Feb 2025 | 3 articles | Viewed by 3580 | Submission Open
Keywords: transcatheter aortic valve implantation; TAVI; aortic valve stenosis; interventional cardiac surgery; heart valve disease
(This special issue belongs to the Section Cardiovascular Medicine)
Innovations and Management of Cardiovascular, Respiratory, and Complex Conditions in Anesthesia and Critical Care Medicine
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3564 | Submission Open
Keywords: respiratory failure; emergency management; critical care medicine; airway management; mechanical ventilation; sepsis management; acute respiratory distress syndrome (ARDS); point-of-care ultrasound; critical care ultrasound; noninva-sive respiratory support; heart failure; respiratory failure
(This special issue belongs to the Section Pulmonology)
Updates on Interstitial Lung Disease
edited by and Sameep Sehgal
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3447 | Submission Open
Keywords: interstitial lung disease; idiopathic pulmonary fibrosis; lung transplantation; connective tissue disease; bronchoscopy
(This special issue belongs to the Section Pulmonology)
Cerebrovascular Disease: Symptoms, Diagnosis and Current Treatment
edited by Alba Scerrati and Giorgio Mantovani
submission deadline 28 Feb 2025 | 3 articles | Viewed by 3216 | Submission Open
Keywords: ischemic stroke; cerebral aneurysms; cerebral vascular malformation; cerebral venous disease; cerebral venous thrombosis
(This special issue belongs to the Section Clinical Neurology)
Current Practice and Future Perspectives in Laryngeal Surgery
edited by
submission deadline 28 Feb 2025 | 3 articles | Viewed by 3158 | Submission Open
Keywords: laryngeal disorders; laryngeal surgery; microsurgery; endoscopic surgery; open surgery; laser surgery
(This special issue belongs to the Section Otolaryngology)
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