Precision Medicine in Breast Cancer: Challenges and Opportunities in Diagnostic and Therapeutic Purposes
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".
Deadline for manuscript submissions: closed (25 September 2021) | Viewed by 21791
Special Issue Editor
Interests: mitochondrial medicine; free radical biology; reproduction; cancer biology; chronic diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Breast cancer emergencies have become a rapidly evolving field in medicine over the last ten years. Carcinogenesis is a multiparametric process that involves diverse factors such as genetic, environmental, or aging. Recent research that elucidates the tumor biology and molecular pathways that mediate cancer progression and drug resistance has led to the development of various molecular targeted therapies involving monoclonal antibodies, small molecule receptor tyrosine kinase inhibitors, and agents blocking downstream signaling pathways in breast cancer. Breast cancer has become a prominent example of the success of precision medicine in treating solid tumor malignancies. The first step in this process involves new blood-based diagnostics, which can now noninvasively provide clinically useful information. However, the identification of novel biomarkers that could be used in early diagnosis is urgently needed, especially for guiding initial therapy and predicting relapse or drug resistance following the administration of novel targeted therapies. In this Special Issue, we invite research and review papers in any area of breast cancer, including but not limited to fundamental understanding of oncogenomics and cancer signaling pathways, diagnostic, prognostic, and pharmacogenomic biomarkers, molecular diagnosis by gene expression profiling, molecular targets driving the progression of human breast cancer, cancer drug development on these targets, and clinical trials with new agents and cancer epigenetics.
Dr. Chia-Jung Li
Guest Editor
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Keywords
- Breast cancer
- Molecular heterogeneity
- Biomarkers
- Signaling pathways
- Targeted therapies
- Development of novel drugs
- Preclinical models
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