New Advances and Perspectives in Ophthalmology: Progress and Modern Challenges

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1587

Special Issue Editor


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Guest Editor
Eye Unit "Luigi Curto" Hospital, Azienda Sanitaria Locale Salerno, 84035 Polla, Salerno, Italy
Interests: ophthalmology; medical retina; ocular ultrasound; optical coherence tomography; OCT; optic nerve diseases; glaucoma
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the field of Ophthalmology has been constantly updated, thanks to the development of increasingly modern technologies that have allowed significant progress in diagnosing, managing, and treating ocular pathologies.

In particular, ocular diagnostic technology (optical coherence tomography, optical coherence tomography angiography, ocular ultrasound, etc.), as well as new genetic discoveries, have provided new insights and increased our knowledge about several ocular diseases, such as retinal and choroidal diseases, ocular oncology, optic nerve diseases, and anterior segment diseases, which poses a compelling challenge in Ophthalmology.

This Special Issue will aim to promote research on the new advances and perspectives in Ophthalmology, going from diseases’ etiology to the diagnosis and the tailored treatment of ophthalmic pathologies, trying to better understand the nature of these challenging ocular conditions and how to properly deal with them.

Dr. Livio Vitiello
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • clinical ophthalmology
  • eye diseases
  • retinal diseases
  • corneal diseases
  • optic nerve diseases
  • glaucoma
  • dry eye disease
  • maculopathies
  • choroidal diseases
  • ocular oncology

Published Papers (2 papers)

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Review

18 pages, 2222 KiB  
Review
Ocular Manifestations and Complications of Patent Foramen Ovale: A Narrative Review
by Filippo Lixi, Luca Fazzini, Claudia Cannas, Roberta Montisci and Giuseppe Giannaccare
J. Pers. Med. 2024, 14(7), 695; https://doi.org/10.3390/jpm14070695 - 27 Jun 2024
Viewed by 775
Abstract
Patent foramen ovale (PFO) is a prevalent congenital cardiac anomaly associated with a persistent opening between the atrial septum, allowing communication between the left and right atria. Despite often being asymptomatic, PFO can lead to various clinical presentations, including cryptogenic stroke and other [...] Read more.
Patent foramen ovale (PFO) is a prevalent congenital cardiac anomaly associated with a persistent opening between the atrial septum, allowing communication between the left and right atria. Despite often being asymptomatic, PFO can lead to various clinical presentations, including cryptogenic stroke and other embolic events. Transient visual disturbances, alterations in the visual field, migraine with aura, impaired eye movement and endogenous eye infections may prompt patients to seek ophthalmological consultation. Understanding these diverse clinical scenarios is crucial for early detection, appropriate management and mitigating the morbidity burden associated with PFO. This narrative review aims at examining the spectrum of clinical presentations of ocular pictures associated with PFO. The pathophysiology, diagnosis and treatment methods for PFO will be described, emphasizing the importance of a multidisciplinary approach involving ophthalmologists, cardiologists, neurologists and imaging specialists. In the future, prospective studies and clinical trials are warranted to provide further insights into the preventive role and optimal therapeutic strategies for managing PFO-related ocular complications, ultimately guiding clinical decision making and optimizing patient care. Full article
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21 pages, 1773 KiB  
Review
The Role of Oral Supplementation for the Management of Age-Related Macular Degeneration: A Narrative Review
by Angela D’Angelo, Livio Vitiello, Vincenzo Gagliardi, Giulio Salerno, Ilaria De Pascale, Alessia Coppola, Giulia Abbinante, Alfonso Pellegrino and Giuseppe Giannaccare
J. Pers. Med. 2024, 14(6), 653; https://doi.org/10.3390/jpm14060653 - 18 Jun 2024
Viewed by 610
Abstract
The majority of neurodegenerative eye disorders occur with aging and significantly impair quality of life. Age-related macular degeneration (AMD) is the third most common cause of visual impairment and blindness worldwide. One of the most important elements in the pathophysiology of neurodegenerative eye [...] Read more.
The majority of neurodegenerative eye disorders occur with aging and significantly impair quality of life. Age-related macular degeneration (AMD) is the third most common cause of visual impairment and blindness worldwide. One of the most important elements in the pathophysiology of neurodegenerative eye disease is certainly oxidative stress, with neuroinflammation and ocular ischemia which may also be significant factors. Antioxidants, either by food or oral supplementation, may be able to mitigate the deleterious effects of reactive oxygen species that build as a result of oxidative stress, ischemia, and inflammation. Over the past few decades, a number of research works examining the potential adjuvant impact of antioxidants in AMD have been published. In fact, there is not only more and more interest in already known molecules but also in new molecules that can help clinicians in the management of this complex multifactorial disease, such as astaxanthin and melatonin. However, while some studies showed encouraging outcomes, others were conflicting. In addition, more and more attention is also being paid to nutrition, considered a pivotal key point, especially to prevent AMD. For this reason, the purpose of this review is to analyze the main antioxidant molecules currently used as oral supplements for AMD treatment, as well as the role of diet and food intake in this ocular disease, to better understand how all these factors can improve the clinical management of AMD patients. Full article
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