Molecular Mechanisms and Treatment of Retinal Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 722
Special Issue Editors
Interests: retinal ischemic diseases; anti-aging; anti-Inflammation; neuroprotection; retinal metabolism; nutritional supplements; bioinformatics; vitamins; retinal dysfunction; fibrosis; peroxisome proliferator-activated receptor; hypoxia-inducible factor; nicotinamide adenine dinucleotide; drug delivery; experimental model development; pathology
Special Issues, Collections and Topics in MDPI journals
Interests: ophthalmology; ocular ultrasound; medical retina; retinal diseases; glaucoma
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The retina in the eye is essential for vision and is highly vulnerable to a range of pathological insults. Retinal degeneration due to aging, inflammation, and vascular damage remains a major cause of irreversible vision loss worldwide. In recent years, significant attention has been directed toward the role of metabolic regulation in maintaining retinal health, particularly in the context of high myopia, age-related macular degeneration, and glaucoma. Clinical and experimental studies suggest that targeted nutrients may exert protective effects by reducing oxidative stress, modulating inflammation, and preserving retinal integrity. Furthermore, innovative therapies such as cell-based treatments and advanced drug delivery systems, including eye drops capable of crossing ocular barriers, have emerged as promising strategies to restore or preserve vision. Light therapy has also gained interest as a non-invasive modality to modulate retinal physiology and potentially slow down degenerative progression.
This Special Issue will focus on recent advances across multiple fronts—including nutritional interventions, optometric management, regenerative therapies, drug delivery innovations, and digital health applications to address retinal degeneration, ischemia, and inflammatory retinal disorders in various eye diseases. By bringing together cutting-edge research and clinical insights, this collection can inspire new therapeutic strategies that can protect vision and enhance quality of life worldwide.
Dr. Deokho Lee
Dr. Livio Vitiello
Guest Editors
Manuscript Submission Information
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Keywords
- nutritional supplementations
- high myopia
- optometry
- cell therapy
- drug delivery
- age-related macular degeneration
- glaucoma
- retinal degeneration
- choroidal thinning
- scleral remodeling
- light therapy
- digital healthcare
- prematurity of retionopathy
- carotid artery occlusion
- retinal ischemia
- inflammation
- eye drop
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