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Special Issues
Towards Precision Anesthesia and Pain Management
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Towards Precision Anesthesia and Pain Management

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 616

Special Issue Editors

Prof. Dr. Giustino Varrassi

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Guest Editor
Paolo Procacci Foundation, Rome, Italy
Interests: pain medicine; anesthesiology
Special Issues, Collections and Topics in MDPI journals
Dr. Joseph V. Pergolizzi

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Guest Editor
NEMA Research Inc., 868 106th Ave North, Naples, FL 34108, USA
Interests: perioperative and pain medicine; critical and palliative care; pharmacology and drug development
Dr. Filomena Puntillo

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Guest Editor
Anaesthesia, Intensive Care and Pain Unit, Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Piazza G. Cesare 11, 70124 Bari, Italy
Interests: anesthesiology; pain therapy; intensive care; acute postoperative pain; oncologic pain

Special Issue Information

Dear Colleagues,

Precision Medicine is a growing necessity in the clinical approach to patients. This obviously also applies to Anesthesiology and Pain Medicine, which are two important aspects in clinical medicine, especially because they are both very challenging.

The main aim of this Special Issue is to collect all the information that our colleagues involved both in the everyday clinical practice and in research are willing to share with the rest of the scientific world. Communication, especially publication, is always the best way to make aware the others of the results of our experiences. This Special Issue should provide the most updated information on the topic.

We are soliciting mainly review articles, both narrative or systematic, but also meta-analysis and original research.

Prof. Dr. Giustino Varrassi
Dr. Joseph V. Pergolizzi
Dr. Filomena Puntillo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • precision medicine
  • anesthesia
  • pain medicine

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

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Research

13 pages, 486 KiB  
Article
Emergency Awake Laparotomy Using Neuraxial Anaesthesia: A Case Series and Literature Review
by Matteo Luigi Giuseppe Leoni, Tommaso Rossi, Marco Mercieri, Giorgia Cerati, David Michael Abbott, Giustino Varrassi, Gaetano Cattaneo, Patrizio Capelli, Manuela Mazzoni and Ruggero Massimo Corso
J. Pers. Med. 2024, 14(8), 845; https://doi.org/10.3390/jpm14080845 - 9 Aug 2024
Viewed by 352
Abstract
Emergency laparotomy is a surgical procedure associated with significantly higher mortality rates compared to elective surgeries. Awake laparotomy under neuraxial anaesthesia has recently emerged as a promising approach in abdominal surgery to improve patient outcomes. This study aims to evaluate the feasibility and [...] Read more.
Emergency laparotomy is a surgical procedure associated with significantly higher mortality rates compared to elective surgeries. Awake laparotomy under neuraxial anaesthesia has recently emerged as a promising approach in abdominal surgery to improve patient outcomes. This study aims to evaluate the feasibility and potential benefits of using neuraxial anaesthesia as the primary anaesthetic technique in emergency laparotomies. We conducted a case series involving 16 patients who underwent emergency laparotomy for bowel ischemia, perforation, or occlusion. Neuraxial anaesthesia was employed as the main anaesthetic technique. We analysed patient demographics, clinical characteristics, intraoperative details, and postoperative outcomes. The primary outcome measures included the adequacy of postoperative pain control, the incidence of postoperative complications, and mortality rates. Among the 16 patients, adequate postoperative pain control was achieved, with only 2 patients requiring additional analgesia. Postoperative complications, including sepsis, wound dehiscence, and pneumonia, were observed in seven patients (44%). The observed mortality rate was relatively low at 6% (one patient). Notably, conversion to general anaesthesia was not necessary in any of the cases, and no early readmissions were reported. Our findings highlight the feasibility and potential benefits of using neuraxial anaesthesia in emergency laparotomies. The observed low mortality rate and the avoidance of conversion to general anaesthesia suggest that neuraxial anaesthesia may be a useful alternative in emergency settings. However, the occurrence of postoperative complications in 44% of patients indicates the need for cautious patient selection and close monitoring. Further research with larger sample sizes is warranted to fully elucidate the efficacy, safety, and potential impact of this technique on patient outcomes in emergency laparotomies. Full article
(This article belongs to the Special Issue Towards Precision Anesthesia and Pain Management)
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