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Life
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Non-invasive Optical Methods in Physiology or Medicine
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Non-invasive Optical Methods in Physiology or Medicine

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2574

Special Issue Editors

Dr. Maxim E. Darvin

E-Mail Website
Guest Editor
Independent Researcher, 10178 Berlin, Germany
Interests: skin physiology; skin barrier function; non-invasive analysis; photoprotection; antioxidants; spectroscopy; microscopy
Special Issues, Collections and Topics in MDPI journals
Dr. Luis Oliveira

E-Mail Website1 Website2
Guest Editor
1. Center of Innovation in Engineering and Industrial Technology, ISEP, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal
2. Physics Department, School of Engineering, Polytechnic Institute of Porto, Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal
Interests: biomedical optics; biophotonics; tissue optical clearing; optical methods for cancer detection; ultraviolet spectroscopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Non-invasive methods are crucial, are constantly being improved and are increasingly used in various fields of physiology and medicine. Optical methods include numerous spectroscopic and laser technologies based on fluorescence, vibrational and imaging techniques, which offer a number of advantages in in vivo human applications and are irreplaceable in dermatology, skin physiology and endoscopy, mainly because of the high resolution, specificity to certain substances and compartments, quickness and non-invasiveness of the measurements.

This Special Issue aims to present the current state-of-the-art research or comprehensive reviews on the application of optical methods including but not limiting to spectroscopic, fluorescence, vibrational and imaging techniques, that are already used or have the potential to be used in physiology or medicine for non-invasive in vivo diagnostics, visualization (“optical biopsy”), treatment and drug delivery control. This Special Issue will provide readers with an up-to-date information on the application of biophotonics in physiology and medicine. We welcome researches from academia or the biophotonics industry to submit original or review manuscripts and look forward to your contributions.

Dr. Maxim E. Darvin
Dr. Luis Oliveira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biophotonics
  • imaging
  • microscopy
  • spectroscopy
  • fluorescence
  • FLIM
  • Raman
  • in vivo
  • diagnostics
  • drug delivery

Published Papers (2 papers)

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Research

9 pages, 3357 KiB  
Communication
Thermographic Changes following Short-Term High-Intensity Anaerobic Exercise
by Nir Fink, Shai Bogomilsky, Avi Raz, Oshrit Hoffer and Mickey Scheinowitz
Life 2023, 13(11), 2175; https://doi.org/10.3390/life13112175 - 07 Nov 2023
Viewed by 1081
Abstract
Current studies report thermographic changes following aerobic or resistance exercise but not short, vigorous anaerobic exercise. Therefore, we investigated body surface temperature changes using thermal imaging following a short session of anaerobic exercise. We studied three different regions of interest (ROIs): the legs, [...] Read more.
Current studies report thermographic changes following aerobic or resistance exercise but not short, vigorous anaerobic exercise. Therefore, we investigated body surface temperature changes using thermal imaging following a short session of anaerobic exercise. We studied three different regions of interest (ROIs): the legs, chest, and forehead. Thermal imaging for each participant was performed before and immediately after completing a Wingate anaerobic test and every minute during a 15 min recovery period. Immediately after the test, the maximum temperature was significantly higher in all ROIs (legs, p = 0.0323; chest, p = 0.0455; forehead, p = 0.0444) compared to pre-test values. During the recovery period, both legs showed a significant and continuous temperature increase (right leg, p = 0.0272; left leg, p = 0.0382), whereas a non-significant drop was noted in the chest and forehead temperatures. Additionally, participants with a lower anaerobic capacity exhibited a higher delta increase in surface leg temperature than participants with higher anaerobic capacities, with a minimal change in surface leg temperature. This is the first study to demonstrate body surface temperature changes following the Wingate anaerobic test. This temperature increase is attributed to the high anaerobic mechanical power outputs achieved by the leg muscles and the time taken for temperature reduction post-exercise. Full article
(This article belongs to the Special Issue Non-invasive Optical Methods in Physiology or Medicine)
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16 pages, 6700 KiB  
Article
Correlation between the Capillary Blood Flow Characteristics and Endothelium Function in Healthy Volunteers and Patients Suffering from Coronary Heart Disease and Atrial Fibrillation: A Pilot Study
by Petr Ermolinskiy, Yury Gurfinkel, Egor Sovetnikov, Andrei Lugovtsov and Alexander Priezzhev
Life 2023, 13(10), 2043; https://doi.org/10.3390/life13102043 - 12 Oct 2023
Cited by 1 | Viewed by 867
Abstract
Coronary heart disease (CHD) and atrial fibrillation (AF) pose significant health risks and require accurate diagnostic tools to assess the severity and progression of the diseases. Traditional diagnostic methods have limitations in providing detailed information about blood flow characteristics, particularly in the microcirculation. [...] Read more.
Coronary heart disease (CHD) and atrial fibrillation (AF) pose significant health risks and require accurate diagnostic tools to assess the severity and progression of the diseases. Traditional diagnostic methods have limitations in providing detailed information about blood flow characteristics, particularly in the microcirculation. This study’s objective was to examine and compare the microcirculation in both healthy volunteers and patient groups with CHD and AF. Furthermore, this study aimed to identify a relationship between blood microcirculation parameters and endothelial function. Digital capillaroscopy was employed to assess the microcirculation parameters, for example, such as capillary blood flow velocity, the size of red blood cell aggregates, and the number of aggregates per min and per running mm. The results indicate significant alterations in blood flow characteristics among patients with CHD and AF compared to healthy volunteers. For example, capillary blood flow velocity is statistically significantly decreased in the case of CHD and AF compared to the healthy volunteers (p < 0.001). Additionally, the correlation between the measured parameters is different for the studied groups of patients and healthy volunteers. These findings highlight the potential of digital capillaroscopy as a non-invasive tool for evaluating blood flow abnormalities (red blood cell aggregates and decreased capillary blood flow velocity) in cardiovascular diseases, aiding in early diagnosis and disease management. Full article
(This article belongs to the Special Issue Non-invasive Optical Methods in Physiology or Medicine)
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