Altered Cellular Pathways in Human Health and Diseases
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (18 August 2023) | Viewed by 1415
Special Issue Editors
Interests: cancer; signaling pathways; therapy; metabolism; in silico
Special Issues, Collections and Topics in MDPI journals
Interests: cancer; signaling pathways; therapy; metabolism; in silico
Special Issue Information
Dear Colleagues,
A regulatory molecular pathway is important for the proper functioning and homeostasis of the human body. Alteration in the cellular pathways by a wide range of factors, such as diet, molecular environment, genetic behavior, etc., plays an important role in the progression of various diseases. Changes in bioenergetics pathways, including carbohydrate metabolism, lipid metabolism, amino acid metabolism and others, regulate a number of crucial factors inside the cells. A change or imbalance of all these factors inside the cells sends a message via cellular cell and response to their molecular machinery to perform cellular homeostasis-associated functions. In continuation of this, different signaling pathways, such as JAK STAT, NFkB, Notch, AMPK, Akt, Apoptosis, Estrogen, Insulin, MAPK, mTOR signaling and others, also maintain cellular homeostasis inside the cell. During disease, alterations in metabolism pathways, signaling pathways and other crucial pathways involved in the physiological homeostasis of the human body become noteworthy factors for the development of different diseases, including life-threatening diseases such as cancer, neurodegenerative diseases and others.
In this Special Issue, we invite the submission of original research articles (in vitro, animal and human studies, as well as in silico studies), review articles and perspectives that could stimulate the continuing efforts to better understand the cellular pathways and associated disease and their therapy. We welcome submissions from a broad range of topics, including (but not limited to) the following: immune factors, mechanisms of action, pathogenesis, aggressiveness of disease, experimental therapeutics, etc.
Dr. Prem P. Kushwaha
Dr. Shashibhal M Pandey
Dr. Jayadev Joshi
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pathways
- disease
- drug
- metabolism
- cancer
