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Life, Volume 15, Issue 9

September 2025 - 159 articles

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Cover Story: Coronary microvascular dysfunction (CMD) is increasingly recognized across diverse cardiovascular diseases and linked to adverse outcomes. Several imaging modalities—positron emission tomography, computed tomography, cardiac magnetic resonance, myocardial contrast echocardiography, and transthoracic Doppler echocardiography—are proven to quantify coronary flow reserve and myocardial blood flow, both valuable markers of CMD. Furthermore, a growing number of studies have attempted to correlate CMD indices with systolic myocardial function markers, such as left ventricular ejection fraction, global longitudinal strain, and myocardial work indices. This review presents the current evidence on CMD imaging and examines the association between CMD indices and systolic function in cardiovascular diseases. View this paper

Articles (159)

  • Article
  • Open Access
539 Views
13 Pages

The Human Penile Fibro-Vascular Assembly Requires the Integrity of Ten Fibro-Ligaments

  • Heng-Shuen Chen,
  • Chu-Wen Fang,
  • Raymond W. M. Tsai,
  • Chih-Yuan Hsu,
  • Geng-Long Hsu,
  • Hsiu-Chen Lu,
  • Mang-Hung Tsai and
  • Jeff S. C. Chueh

22 September 2025

Introduction: Penile fibro-ligaments have been extensively studied for many centuries; however, there is, unfortunately, a lack of thorough understanding. We aimed to bridge the research gap between anatomy and surgical reconstruction. Methods: We ex...

  • Article
  • Open Access
320 Views
24 Pages

Use of Two PGPB Strains for the Valorization of Wastewater Sludge and Formulation of a Biofertilizer for the Recovery of Quercus ilex

  • Vanesa M. Fernández-Pastrana,
  • Daniel González-Reguero,
  • Marina Robas-Mora,
  • Diana Penalba-Iglesias,
  • María José Pozuelo de Felipe,
  • Agustín Probanza and
  • Pedro Jiménez-Gómez

22 September 2025

In response to the growing demand for agricultural production and the need for more sustainable practices, the use of biofertilizers based on the valorization of agricultural residues is presented as an alternative to traditional chemical fertilizers...

  • Article
  • Open Access
406 Views
15 Pages

Machine Learning Approaches for Early Identification of Subclinical Ketosis and Low-Grade Ruminal Acidosis During the Transition Period in Dairy Cattle

  • Samanta Arlauskaitė,
  • Akvilė Girdauskaitė,
  • Dovilė Malašauskienė,
  • Mindaugas Televičius,
  • Karina Džermeikaitė,
  • Justina Krištolaitytė,
  • Gabija Lembovičiūtė,
  • Greta Šertvytytė and
  • Ramūnas Antanaitis

22 September 2025

This study evaluated six supervised machine learning (ML) models for early detection of subclinical ketosis and low-grade ruminal acidosis in dairy cows during the transition period. Ninety-four Holstein cows were monitored for 21 days postpartum usi...

  • Article
  • Open Access
307 Views
17 Pages

Rootstock Genotype Dictates Phosphorus Deficiency Tolerance and Transcriptional Plasticity in Grafted Camellia oleifera Plants

  • Zhihua Ren,
  • Juan Liu,
  • Jin Zeng,
  • Li Cheng,
  • Huiyun Liu,
  • Yunyu Zhang,
  • Qinhua Cheng,
  • Wenjuan Su,
  • Huaiyuan Wu and
  • Dongnan Hu

22 September 2025

Rootstock choice offers a powerful lever for tailoring economically important trees to adverse environments. Camellia oleifera Abel., a premier oil-producing species cultivated widely on red-soil hills, suffers large yield losses under chronic phosph...

  • Review
  • Open Access
350 Views
17 Pages

Diagnostic and Therapeutic Particularities of Sepsis in Hemodialysis Patients

  • Maria-Daniela Tanasescu,
  • Andrei-Mihnea Rosu,
  • Alexandru Minca,
  • Andreea-Liana Rosu,
  • Maria-Mihaela Grigorie,
  • Delia Timofte and
  • Dorin Ionescu

22 September 2025

Background: Sepsis is a leading cause of morbidity and mortality among patients receiving maintenance hemodialysis (HD), reflecting a unique combination of immunologic dysfunction, comorbidities, and healthcare-related exposures. Despite advances in...

  • Brief Report
  • Open Access
361 Views
15 Pages

22 September 2025

In recent years, in response to the demand for the livestock industry to enhance cattle production performance, scholarly inquiries have centered on elucidating the underlying mechanisms by which feed additives modulate rumen microenvironment and met...

  • Case Report
  • Open Access
821 Views
16 Pages

Ultrasound-Guided Prolotherapy for Sciatica Secondary to Sacrospinous Ligament Calcification: A Potential and Previously Overlooked Etiological Factor in Deep Gluteal Syndrome—A Case Report and Literature Review

  • Yonghyun Yoon,
  • King Hei Stanley Lam,
  • Jaeyoung Lee,
  • Rowook Park,
  • Jaehyun Shim,
  • Jonghyeok Lee,
  • Daniel Chiung-Jui Su,
  • Kenneth Dean Reeves and
  • Stephen Cavallino

22 September 2025

Background: Deep gluteal syndrome (DGS) is an underdiagnosed cause of sciatica-like pain, involving the entrapment of the sciatic nerve by various structures within the subgluteal space. While cases of ossification or calcification in the context of...

  • Article
  • Open Access
369 Views
18 Pages

Drought Tolerance Evaluation and Classification of Foxtail Millet Core Germplasms Using Comprehensive Tolerance Indices

  • Yun Zhao,
  • Jun Liu,
  • Zaituniguli Kuerban,
  • Hui Wang,
  • Baiyi Yang,
  • Hong-Jin Wang,
  • Xiangwei Hu,
  • Nadeem Bhanbhro and
  • Guojun Feng

22 September 2025

Drought stress critically constrains agricultural productivity in arid and semi-arid regions, necessitating the development of drought-tolerant crop varieties for sustainable food security. This study evaluated drought tolerance in 222 foxtail millet...

  • Review
  • Open Access
1,546 Views
13 Pages

Importance of Using Sunscreen After Light or Laser Facial Treatment: A Literature Review

  • Kar Wai Alvin Lee,
  • Lisa Kwin Wah Chan,
  • Jong Keun Song,
  • Cheuk Hung Lee,
  • Jin-Hyun Kim and
  • Kyu-Ho Yi

22 September 2025

Background: The application of sunscreen after light and laser facial treatments is vital for optimizing patient outcomes and minimizing complications. This review aims to highlight the importance of sunscreen use in post-procedural care within aesth...

  • Article
  • Open Access
411 Views
19 Pages

The Prognostic Role of the Left Atrium in Hypertensive Patients with HFpEF: Does Function Matter More than Structure?

  • Artem Ovchinnikov,
  • Alexandra Potekhina,
  • Anastasiia Filatova,
  • Olga Svirida,
  • Maria Sobolevskaya,
  • Alfiya Safiullina and
  • Fail Ageev

21 September 2025

Background: In arterial hypertension (AH), adverse hemodynamic consequences in the left atrium (LA) are often observed. The prognostic significance of functional vs. structural LA abnormalities among high-risk AH patients (with heart failure with pre...

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