Life, Volume 15, Issue 9
September 2025 - 159 articles
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Cover Story: Coronary microvascular dysfunction (CMD) is increasingly recognized across diverse cardiovascular diseases and linked to adverse outcomes. Several imaging modalities—positron emission tomography, computed tomography, cardiac magnetic resonance, myocardial contrast echocardiography, and transthoracic Doppler echocardiography—are proven to quantify coronary flow reserve and myocardial blood flow, both valuable markers of CMD. Furthermore, a growing number of studies have attempted to correlate CMD indices with systolic myocardial function markers, such as left ventricular ejection fraction, global longitudinal strain, and myocardial work indices. This review presents the current evidence on CMD imaging and examines the association between CMD indices and systolic function in cardiovascular diseases. View this paper