Microglia, Behavior, and Sex Differences: Neuroimmune Mechanisms in Development and Disease
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 28 May 2026 | Viewed by 10
Special Issue Editor
Interests: inflammation; natural products; neuro-inflammation; microalgae; microglia; behavior
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to launch the first edition of the Special Issue of Life, titled "Microglia, Behavior, and Sex Differences: Neuroimmune Mechanisms in Development and Disease."
Microglia, the resident immune cells of the central nervous system, play essential roles not only in immune surveillance but also in shaping brain development, synaptic plasticity, and behavioral outcomes. In recent years, increasing evidence has shown that microglial function implicated in the pathophysiology of numerous neurological and psychiatric disorders, including autism spectrum disorders, depression, Alzheimer's disease, and multiple sclerosis.
This Special Issue aims to gather cutting-edge research that advances our understanding of microglial biology and its impact on neurodevelopment and disease, with a particular focus on behavioral outcomes and sex-specific mechanisms. We welcome original research articles and reviews addressing topics such as microglial ontogeny, sex hormones and neuroinflammation, behavioral consequences of microglial dysregulation, and the development of sex-specific therapeutic strategies.
We believe this Special Issue will serve as a valuable reference for researchers working in the fields of neuroimmunology, behavioral neuroscience, and neurodevelopment. We look forward to your contributions and to fostering interdisciplinary dialog in this dynamic area of research.
Dr. Irene García Domínguez
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- microglia
- neuroinflammation
- sex differences
- neurodevelopment
- behavior
- neuroimmune mechanisms
- brain disorders
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
