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Life
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Common Complications of Pregnancy
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Common Complications of Pregnancy

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Reproductive and Developmental Biology".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 7389

Special Issue Editors

Dr. Florin Gorun

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, Municipal Emergency Clinical Hospital, Timisoara, Romania
Interests: obstetrics; gynecology; infectious disease; maternal–fetal medicine; ultrasound
Special Issues, Collections and Topics in MDPI journals
Dr. Cosmin Citu

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
Interests: obstetrics; maternal–fetal medicine; infectious disease; prediction
Special Issues, Collections and Topics in MDPI journals
Dr. Amanuel Gebremedhin

E-Mail Website
Guest Editor
Curtin School of Population Health, Curtin University, Perth, WA 6101, Australia
Interests: adverse pregnancy outcomes; machine learning; casual inferences

Special Issue Information

Dear Colleagues,

According to the World Health Organization between 2000 and 2020, the maternal mortality rate decreased by about 34% worldwide, with Eastern Europe and South Asia achieving the largest reduction in maternal mortality rates (70% and 67%, respectively). However, maternal mortality is at an unacceptably high level globally, with around 287,000 deaths related to pregnancy and childbirth in 2020, almost 800 women dying every day from preventable causes related to pregnancy and childbirth, and a maternal death occurring almost every two minutes. An important strategy for preventing maternal and neonatal mortality is the early identification of pregnant women with a higher risk for complications during pregnancy. The prevention, therapeutic interventions, and diagnosis of pregnancy and birth complications are ongoing priorities for researchers and practitioners in this field.

This Special Issue aims to provide a collection of manuscripts that present an overview of the latest research on complications of pregnancy and childbirth, including but not limited to gestational diabetes, pre-eclampsia, preterm labor, placenta previa, fetal growth restriction, and intrauterine infection. We desire to additionally explore the short- and long-term consequences of complicated pregnancies regarding maternal and neonatal morbidity and mortality.

Topics will include, but are not limited to, the following:

  • Epidemiology of pregnancy-related complications and maternal or neonatal mortality/morbidity;
  • Short- and long-term consequences of pregnancy-related complications;
  • Diagnosis and prognosis of pregnancy-related complications;
  • New approaches of managing pregnancy complications.

Dr. Florin Gorun
Dr. Cosmin Citu
Dr. Amanuel Gebremedhin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pregnancy
  • high-risk pregnancy
  • preeclampsia
  • fetal growth restriction
  • gestational diabetes mellitus
  • preterm birth
  • placenta previa
  • intrauterine infection
  • maternal mortality
  • neonatal complications

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Published Papers (3 papers)

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11 pages, 522 KiB  
Article
Exploring the Link between Maternal Hematological Disorders during Pregnancy and Neurological Development in Newborns: Mixed Cohort Study
by Ebtisam Bakhsh, Maan Alkhaldi and Mostafa Shaban
Life 2023, 13(10), 2014; https://doi.org/10.3390/life13102014 - 5 Oct 2023
Cited by 7 | Viewed by 1713
Abstract
Maternal hematological disorders during pregnancy may pose a risk to the neurological development of newborns. To investigate the association between maternal hematological disorders during pregnancy and neurological outcomes in newborns, this mixed cohort study was conducted on 200 pregnant women diagnosed with hematological [...] Read more.
Maternal hematological disorders during pregnancy may pose a risk to the neurological development of newborns. To investigate the association between maternal hematological disorders during pregnancy and neurological outcomes in newborns, this mixed cohort study was conducted on 200 pregnant women diagnosed with hematological disorders during pregnancy. Some cases have been identified in the past who have completed the pregnancy in full, as well as cases in pregnancy. Currently, the children of all mothers have been followed up to evaluate the neurological outcomes of the children at the age of three months. Logistic regression analysis was used to determine the association between maternal hematological disorders and neurological outcomes in newborns. Children born to mothers with hematological disorders had a higher risk of developmental delays (OR = 1.50, 95% CI = 0.90–2.50), cognitive impairments (OR = 1.80, 95% CI = 1.20–2.70), and motor impairments (OR = 1.60, 95% CI = 1.00–2.50) compared to children born to mothers without hematological disorders. Hemophilia was associated with the highest risk of neurological outcomes (developmental delay: OR = 2.80, 95% CI = 1.60–4.90; cognitive impairment: OR = 3.20, 95% CI = 2.00–5.10; motor impairment: OR = 2.60, 95% CI = 1.50–4.60). Conclusion: Our study suggests that maternal hematological disorders during pregnancy may increase the risk of negative neurological consequences in newborns. Further research is needed to identify potential mechanisms and explore preventive measures. Full article
(This article belongs to the Special Issue Common Complications of Pregnancy)
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12 pages, 1551 KiB  
Article
Foley Catheter as a Tourniquet for Hemorrhage Prevention during Peripartum Hysterectomy in Patients with Placenta Accreta Spectrum (PAS)—A Hospital-Based Study
by Jakub Staniczek, Maisa Manasar-Dyrbuś, Ewa Winkowska, Kaja Skowronek and Rafał Stojko
Life 2023, 13(8), 1774; https://doi.org/10.3390/life13081774 - 19 Aug 2023
Viewed by 2657
Abstract
Background: Placenta accreta spectrum (PAS) is a clinical entity significantly increasing the risk of a peripartum hemorrhage. Various surgical methods have been described in the literature, which aim to reduce the risk of bleeding, although they often lack reproducibility and have been performed [...] Read more.
Background: Placenta accreta spectrum (PAS) is a clinical entity significantly increasing the risk of a peripartum hemorrhage. Various surgical methods have been described in the literature, which aim to reduce the risk of bleeding, although they often lack reproducibility and have been performed on low numbers of patients. The aim of this study was to evaluate the use of the Foley catheter as a cervical tourniquet during cesarean sections, in patients with PAS. Methods: All patients who underwent peripartum hysterectomy due to PAS in a large single-center registry were included in the present analysis. The general demographics and clinical characteristics of all participants, including blood loss, and maternal and fetal outcomes, were collected and analyzed. Results: Twelve participants were included. The mean blood loss was 1200 ± 760 ml during operation and the mean ± SD procedural duration was 89 ± 17 min. The median (Q1–Q3) length of hospital stay post-procedurally was 5 (4–6) days. None of the patients required subsequent urgent surgical procedures after hysterectomy. The median (Q1–Q3) packed red blood cell units transfused in our cohort was 2 (0–3). Conclusion: Using the Foley catheter as a tourniquet might be an effective method of excessive bleeding prevention in patients with PAS during peripartum hysterectomy. Full article
(This article belongs to the Special Issue Common Complications of Pregnancy)
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10 pages, 1896 KiB  
Case Report
Scar Ectopic Pregnancy as an Uncommon Site of Ectopic Pregnancy: A Case Report and Literature Review
by Mamoun Elawad, Suad Zaki Hamed Alyousef, Njoud Khaled Alkhaldi, Fayza Ahmed Alamri and Hanadi Bakhsh
Life 2023, 13(11), 2151; https://doi.org/10.3390/life13112151 - 31 Oct 2023
Cited by 1 | Viewed by 2688
Abstract
A cesarean scar pregnancy is a rare type of ectopic pregnancy that occurs when a fertilized egg implants in the scar from a previous cesarean section. It is a serious condition that can lead to significant morbidity and mortality if not managed promptly [...] Read more.
A cesarean scar pregnancy is a rare type of ectopic pregnancy that occurs when a fertilized egg implants in the scar from a previous cesarean section. It is a serious condition that can lead to significant morbidity and mortality if not managed promptly and appropriately. In this literature review and case report, we discuss the etiology, diagnosis, and management of cesarean scar pregnancy. We conducted a comprehensive search of relevant literature using electronic databases and included studies that reported on the diagnosis and management of cesarean scar pregnancy. We also present a case report of a patient with cesarean scar pregnancy who was managed surgically. The diagnosis of cesarean scar pregnancy is primarily done via transvaginal or transabdominal ultrasound, and medical or surgical management can be used depending on the gestational age, hemodynamic status, and patient preferences. The surgical approach, which involves hysteroscopy, laparoscopy, or laparotomy, is usually preferred, since it is associated with fast recovery and lower recurrence rates. However, it is crucial to consider the patient’s plans for future fertility when selecting the management approach. In conclusion, cesarean scar pregnancy is a rare but potentially life-threatening condition that requires prompt and appropriate management. Early diagnosis and treatment can prevent significant morbidity and mortality, and surgical management is usually preferred due to its higher success rates and lower recurrence rates. Full article
(This article belongs to the Special Issue Common Complications of Pregnancy)
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