Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Implications of Bioactive Compounds in Lifelong Disorders submission deadline 31 Mar 2025 | Viewed by 35 | Submission Open
Keywords: phytochemicals; functional food; oxidative stress; metabolic syndrome; neuroinflammation; antioxidant; polyphenols; diabetes; inflammatory bowel disease; natural products; neurodegenerative disease
(This special issue belongs to the Section Pharmaceutical Science)
Current Updates in Pharmacoepidemiology
edited by
submission deadline 31 Mar 2025 | Viewed by 33 | Submission Open
Keywords: pharmacoepidemiology; real-world data; medication safety; machine learning; big data analytics; personalized medicine; drug efficacy; population health; pharmacovigilance
(This special issue belongs to the Section Pharmaceutical Science)
Innovative Approaches in Breast Reconstruction Diagnostics and the Treatment of Complications
edited by Eun Young Rha
submission deadline 31 Mar 2025 | Viewed by 30 | Submission Open
Keywords: breast reconstruction; imaging study; autologous tissue; implant; acellular dermal matrix; surgical outcome; scar
(This special issue belongs to the Section Medical Research)
Molecular and Cellular Biology of Transplantation
edited by Robert Ramm
submission deadline 31 Mar 2025 | Viewed by 23 | Submission Open
Keywords: xeno- and allotransplantation; ex vivo perfusion; costimulatory blockade; CAR Treg; accommodation
(This special issue belongs to the Section Physiology and Pathology)
Novel Approaches and Strategies in Nutrition and Feeding of Animals: 2nd Edition
edited by
submission deadline 31 Mar 2025 | Viewed by 18 | Submission Open
Keywords: animal nutrition; animal production efficiency; animal product quality (milk; eggs; meat); bioactive compounds; sustainability feeding management; advanced grazing management; feed aditives; alternative feed ingredients; fish nutrition; nutrition and health; human health
(This special issue belongs to the Section Animal Science)
Advances in Cardiac Arrest: Prognostic Performance and Management
edited by
submission deadline 31 Mar 2025 | Viewed by 16 | Submission Open
Keywords: cardiac arrest; resuscitation; emergency medicine; critical care medicine
(This special issue belongs to the Section Medical Research)
Plant Physiology: From Omic Analysis toward Physiological Mechanism Research: 2nd Edition
edited by and Fang He
submission deadline 31 Mar 2025 | Viewed by 15 | Submission Open
Keywords: plant physiology; transcriptome; proteomics; gene regulatory network; bioinformation; omics; molecular mechanisms
(This special issue belongs to the Section Plant Science)
Sports Medicine: Nutritional Sciences and Nutritional Biochemistry: 2nd Edition
edited by
submission deadline 31 Mar 2025 | Viewed by 11 | Submission Open
Keywords: sport nutrition; sport supplementation; sport biochemistry; metabolomics; miRNA
(This special issue belongs to the Section Physiology and Pathology)
Exploring the Interplay between Diet, Microbiota, and Cancer submission deadline 31 Mar 2025 | Viewed by 9 | Submission Open
Keywords: microbiota/microbiome and cancer; dysbiosis; environmental pollutants; xenobiotic; metabolic disorders; diet; health/cancer; microbiota– host symbiosis; age diet; probiotics; prebiotics
(This special issue belongs to the Section Microbiology)
Synthesis and Evaluation of Novel Anticancer and Anti-Inflammatory Agents
edited by Po-Jen Chen, and Shun-Hua Chen
submission deadline 31 Mar 2025 | Viewed by 7 | Submission Open
Keywords: anticancer agents; anti-inflammatory agents; pharmacology; molecular and cell biology; drug design; medicinal chemistry; pharmacodynamics; pharmacokinetics; structure– activity relationship (SAR)
(This special issue belongs to the Section Pharmaceutical Science)
The Role of Stem Cells in Retinal Conditions
edited by , Theo Empeslidis and Lorenzo Motta
submission deadline 15 Apr 2025 | Viewed by 73 | Submission Open
Keywords: stem cells; retinal conditions; regenerative medicine; age-related macular degeneration (AMD); retinitis pigmentosa; diabetic retinopathy; induced pluripotent stem cells (iPSCs); cell differentiation; vision restoration; clinical trials
Strategies for Controlling Synthetic Cells: Approaches, Models, Applications
edited by and
submission deadline 22 Apr 2025 | 1 articles | Viewed by 779 | Submission Open
Keywords: artificial cells; bioreactors; biosensor; cell-free systems; coacervates; controlled behavior; DNA signals; drug delivery; gene expression regulation; liposomes; microcompartments; modeling; molecular communication; nanomedicine; nanoparticles; optogenetics; polymersomes; protocells; signaling; stimulus-response; synthetic biology; synthetic cells
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Muscle Wasting, Aging, and Cancer: The Effects of Physical Exercise
edited by
submission deadline 22 Apr 2025 | Viewed by 50 | Submission Open
Keywords: sarcopenia; aging; cancer; muscle wasting; physical exercise; resistance training; satellite cells; inflammation; metabolic health; quality of life
(This special issue belongs to the Section Physiology and Pathology)
Radiological Diagnosis of Cervical Spondylosis and Carotid Artery Disease
edited by Anusha Vaddi
submission deadline 22 Apr 2025 | Viewed by 45 | Submission Open
Keywords: carotid artery disease; atherosclerosis; cervical spondylosis; c-spine; radiological diagnosis; diagnostic accuracy; AI in radiology
(This special issue belongs to the Section Medical Research)
Advances in Non-alcoholic Fatty Liver Disease: Pathophysiology, Diagnosis, and Emerging Therapies submission deadline 26 Apr 2025 | Viewed by 42 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); metabolic dysfunction-associated fatty liver disease (MAFLD); steatohepatitis; metabolic syndrome; insulin resistance; apoptosis/cell death
Sleep and Sleep Disorders in Sports and Advanced Physical Exercise: 2nd Edition submission deadline 30 Apr 2025 | Viewed by 55 | Submission Open
Keywords: sleep; sport; performance; physical exercise; sleep disorders; sleep regimens; fractured sleep; sleep at altitude; sleep medications
(This special issue belongs to the Section Physiology and Pathology)
From Muscle to Fascia: Current Trends and Future Perspectives submission deadline 30 Apr 2025 | Viewed by 36 | Submission Open
Keywords: connective tissue; deep fascia; superficial fascia; retinacula; muscle stiffness; hyaluronan; densification; biomechanics; therapies
(This special issue belongs to the Section Physiology and Pathology)
G Protein-Coupled Receptors: Molecular Mechanisms Involved in Receptor Activation and Selectivity: Second Edition submission deadline 30 Apr 2025 | Viewed by 21 | Submission Open
Keywords: G protein-coupled receptors; chemokines; dimerization; beta arrestin; biased agonist; pain; inflammation; neuroinflammation
(This special issue belongs to the Section Genetics and Genomics)
Obstructive Sleep Apnea and Related Disorders: Pathophysiological Traits and Strategies for Treatment
edited by
submission deadline 5 May 2025 | 4 articles | Viewed by 5283 | Submission Open
Keywords: obstructive sleep apnea; sleep fragmentation; cardiometabolic dysfunction; inflammation; co-morbidities
(This special issue belongs to the Section Physiology and Pathology)
Advances in the Biomedical Applications of Plants and Plant Extracts
edited by and Annamária Pallag
submission deadline 5 May 2025 | 4 articles | Viewed by 3683 | Submission Open
Keywords: herbals; plant extracts; polyphenols; anthocyanins; isolation; characterization; preparation; oxidative stress; apoptosis; inflammation; dermatitis; CNS; new target molecules
(This special issue belongs to the Section Pharmaceutical Science)
Effects of Exercise Training on Muscle Function
edited by Marco Duca and
submission deadline 26 May 2025 | 4 articles | Viewed by 4686 | Submission Open
Keywords: exercise; training; muscle function; resistance training; HIIT
(This special issue belongs to the Section Physiology and Pathology)
Conservative Management of Chronic Disease
edited by
submission deadline 26 May 2025 | 3 articles | Viewed by 2855 | Submission Open
Keywords: chronic disease  ; conservative management; trial protocol; clinical research; interventions
(This special issue belongs to the Section Medical Research)
Plant Biotic and Abiotic Stresses 2024
edited by and
submission deadline 30 May 2025 | 4 articles | Viewed by 3075 | Submission Open
Keywords: plant stress; abiotic stress; biotic stress
(This special issue belongs to the Section Plant Science)
From Stem Cells to Embryos, Congenital Anomalies and Epidemiology
edited by , Soultana Meditskou and
submission deadline 30 Jun 2025 | 4 articles | Viewed by 3702 | Submission Open
Keywords: stem cell research; human embryonic development; birth defects epidemiology; birth defects prevalence; maternal and fetal medicine; congenital anomalies prevention; ultrasound evaluation; pre-birth assessment; prenatal screening; healthcare
(This special issue belongs to the Section Epidemiology)
Musculoskeletal Pain and Disorders: Diagnosis, Treatment and Management submission deadline 30 Jun 2025 | Viewed by 96 | Submission Open
Keywords: pain; connective tissue; musculoskeletal disorders; fascia; muscles; tendons; ligaments
(This special issue belongs to the Section Physiology and Pathology)
Innovative Technologies in Pain Management submission deadline 30 Jun 2025 | Viewed by 34 | Submission Open
Keywords: pain management; extended reality (XR) technologies; gamification for pain relief; psychosocial variables; interdisciplinary approaches
(This special issue belongs to the Section Physiology and Pathology)
Biological Insights into Drug Safety for Vulnerable Populations submission deadline 30 Jun 2025 | Viewed by 29 | Submission Open
Keywords: drug safety; vulnerable populations; pharmacotherapy; drug metabolism and efficacy; pediatric medication safety; drug pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Pharmaceutical Science)
Recent Advances in Crop Genetics and Breeding
edited by Tianxiao Chen, , and Long Chen
submission deadline 31 Aug 2025 | Viewed by 3 | Submission Open
Keywords: crop; high-throughput genotyping; genetic resources; favorable haplotype; marker-assisted selection; genome editing; CRISPR-Cas9; genomic selection
(This special issue belongs to the Section Plant Science)
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