Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Elements Cycling and Plants’ Physiological Characteristics: A Soil–Plant–Atmosphere Continuum Perspective
edited by and
submission deadline 15 Jan 2025 | 2 articles | Viewed by 2384 | Submission Open
Keywords: element cycling; microbial communities; plant nutrition; plant physiology; plant biochemistry; atmospheric composition; climate change; soil– plant– atmosphere interaction; plant– soil feedback
(This special issue belongs to the Section Diversity and Ecology)
Advances in Neuroimaging and Functional Brain Analysis
edited by Gianvincenzo Sparacia
submission deadline 15 Jan 2025 | Viewed by 335 | Submission Open
Keywords: magnetic resonance imaging; resting-state functional magnetic resonance imaging; connectomics; functional connectivity; brain networks; brain diseases assessment
(This special issue belongs to the Section Medical Research)
Advances in Endoscopy for Hepatic, Pancreatic, and Biliary Diseases
edited by John Ong
submission deadline 16 Jan 2025 | Viewed by 95 | Submission Open
Keywords: endoscopic intervention; endoscopic ultrasound; lumen apposing metal stent; radiofrequency ablation; endoscopic sleeve gastroplasty; cholangioscopy; endoscopic retrograde cholangiopancreatography; liver disease; biliary disease; pancreatobiliary disease
(This special issue belongs to the Section Medical Research)
Microbiota in Health and Disease
edited by Amélia Sarmento and
submission deadline 21 Jan 2025 | 4 articles | Viewed by 3566 | Submission Open
Keywords: microbiota; microbiome; dysbiosis; diet; metabolism; immune regulation
(This special issue belongs to the Section Microbiology)
Development and Application of Antimicrobials
edited by , and Adriana Garozzo
submission deadline 21 Jan 2025 | Viewed by 331 | Submission Open
Keywords: antiviral activity; antimicrobial activity; probiotics; bacteriocins; essential oils; natural extracts; drug delivery systems; drug development
(This special issue belongs to the Section Microbiology)
Optical Imaging and Fluorescence Imaging in Breast Cancer Diagnosis and Surgery
edited by , Angelica Conversano and Sanjay Warrier
submission deadline 22 Jan 2025 | 3 articles | Viewed by 5395 | Submission Open
Keywords: optical imaging; fluorescence imaging; breast cancer surgery; breast cancer diagnosis; breast reconstructive surgery; microscopy; breast tumor; lymph node; fluorophore
(This special issue belongs to the Section Medical Research)
Metabolic Health: The Interplay between NAFLD, MAFLD, MASLD and Cardiovascular Disease
edited by and Monika Różycka-Kosmalska
submission deadline 26 Jan 2025 | Viewed by 83 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); metabolic-dysfunction-associated fatty liver disease (MAFLD); metabolic-dysfunction-associated steatotic liver disease (MASLD); cardiovascular disease (CVD); cardiac arrhythmias; structural heart disease; coronary artery disease; hypertension
(This special issue belongs to the Section Medical Research)
Applications of Molecular Dynamics to Biological Systems
edited by
submission deadline 28 Jan 2025 | Viewed by 21 | Submission Open
Keywords: computer simulation; biophysical modeling; molecular dynamics
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Interdisciplinarity in Cardiovascular Diseases: From Pathophysiology to Diagnosis and Treatment—2nd Edition submission deadline 30 Jan 2025 | 4 articles | Viewed by 6935 | Submission Open
Keywords: interdisciplinary team; cardiovascular diseases; cardiovascular complications; gastro-esophago-enterology and hepatology; metabolic associated steato-hepatitis; gut microbiota; nephrocardiology; pulmonary diseases; rheumatology diseases; endocrinology diseases
(This special issue belongs to the Section Physiology and Pathology)
Retinal Diseases: From Molecular Mechanisms to Therapeutics
edited by
submission deadline 30 Jan 2025 | 2 articles | Viewed by 2302 | Submission Open
Keywords: retinal disease; inflammatory disease; genetic diseases; ocular drug development
(This special issue belongs to the Section Physiology and Pathology)
Advanced Strategies in Fracture Treatments
edited by and Chun-Yu Chen
submission deadline 30 Jan 2025 | 2 articles | Viewed by 1427 | Submission Open
Keywords: state of the art; peri-articular fracture; osteoporotic fracture; fragility fracture; treatment protocols
(This special issue belongs to the Section Medical Research)
Acari: Biodiversity, Biogeography and Taxonomy Studies
edited by Pavel B. Klimov
submission deadline 30 Jan 2025 | Viewed by 250 | Submission Open
Keywords: phylogenetics; systematics; evolution and co-evolution; biodiversity; ecology; host associations; role of mites in agriculture and medicine
(This special issue belongs to the Section Animal Science)
Pathogenic Mechanisms, Diagnosis, and Treatment of Hypertension: Insights and Implications
edited by Shengyu Mu and Sankar Devarajan
submission deadline 30 Jan 2025 | Viewed by 217 | Submission Open
Keywords: hypertension; cardiovascular disease; blood pressure; pathogenesis
(This special issue belongs to the Section Physiology and Pathology)
Bone Cancer: From Molecular Mechanism to Treatment
edited by and Syuan-Ling Lin
submission deadline 30 Jan 2025 | Viewed by 29 | Submission Open
Keywords: bone cancer; metastasis; angiogenesis; targeted drugs; biomarkers
(This special issue belongs to the Section Medical Research)
Advances and Applications of Sport Physiology
edited by and
submission deadline 31 Jan 2025 | 5 articles | Viewed by 7011 | Submission Open
Keywords: sports medicine; strength and conditioning; diagnostics; sport injuries; performance analysis
(This special issue belongs to the Section Physiology and Pathology)
Novel Finding in Urological Cancer Genomics
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1039 | Submission Open
Keywords: bladder cancer; prostate cancer; renal cell carcinoma; upper tract urothelial carcinoma
(This special issue belongs to the Section Genetics and Genomics)
Feature Papers in Medical Research: 3rd Edition
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 475 | Submission Open
Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research
(This special issue belongs to the Section Medical Research)
Advancements in Heart Failure Research
edited by Tzu-Hurng Cheng and
submission deadline 31 Jan 2025 | Viewed by 396 | Submission Open
Keywords: cardiac remodeling; biomarkers; precision medicine; patient-centered care; therapeutic innovations
(This special issue belongs to the Section Medical Research)
Feature Paper in Physiology and Pathology: 2nd Edition
edited by and Eleni Stamellou
submission deadline 31 Jan 2025 | 1 articles | Viewed by 351 | Submission Open
Keywords: applied physiology; biomechanics; cardiovascular pathobiology; cell physiology; comparative pathology; comparative physiology
(This special issue belongs to the Section Physiology and Pathology)
Cardioncology: From Molecular Mechanisms to Advanced Imaging and New Treatments
edited by , Giuseppe Pacileo and
submission deadline 31 Jan 2025 | Viewed by 260 | Submission Open
Keywords: cardiotoxicity; echocardiography; cardiac magnetic resonance; cardiac computed tomography; serum cardiac biomarkers; cancer therapy; arrhythmias; cardiotoxicity treatment
(This special issue belongs to the Section Physiology and Pathology)
New Trends in Otorhinolaryngology submission deadline 31 Jan 2025 | Viewed by 182 | Submission Open
Keywords: head and neck; otolaryngology; hearing loss; speech disorders; swallowing disorders; cancer; microRNA; nose; plastic surgery
(This special issue belongs to the Section Medical Research)
Novel Diagnostic and Therapeutic Approaches in Congenital Heart Diseases submission deadline 31 Jan 2025 | Viewed by 170 | Submission Open
Keywords: congenital heart disease; echocardiography; interventional cardiology; multimodal imaging; heart surgery
(This special issue belongs to the Section Medical Research)
Advancements in Postoperative Management of Patients after Surgery
edited by , , and Alessandro Cappellani
submission deadline 31 Jan 2025 | Viewed by 101 | Submission Open
Keywords: surgery; ERAS; postoperative management; recovery; pain
(This special issue belongs to the Section Medical Research)
Fertility Preservation and Sterility Treatment
edited by
submission deadline 31 Jan 2025 | Viewed by 83 | Submission Open
Keywords: fertility preservation; oncofertility; cryopreservation; basic research; gonadotoxicity; oocyte cryopreservation; sperm cryopreservation; ovarian tissue transplantation; assisted reproductive technologies
Plant Functional Genomics and Breeding
edited by
submission deadline 31 Jan 2025 | Viewed by 81 | Submission Open
Keywords: functional genomics; biological breeding; gene cloning; molecular network; genetic improvement
(This special issue belongs to the Section Plant Science)
Pancreatic Cancer Long Survivals
edited by Francesco Leonardi and
submission deadline 31 Jan 2025 | Viewed by 59 | Submission Open
Keywords: pancreatic cancer; long survival; outcome; pancreatic adenocarcinoma; long-term survival; surgical resection; chemotherapy; NGS
(This special issue belongs to the Section Physiology and Pathology)
Common and Novel Markers of Inflammation and Tissue Damage in Various Pathological Conditions submission deadline 31 Jan 2025 | Viewed by 48 | Submission Open
Keywords: body fluids; cytokines; damage-associated molecular patterns (DAMPS); inflammatory response; injury; markers of inflammation and tissue damage; metalloproteinases; novel markers; pathological conditions; proteasome; tissue damage; tissue repair processes; various diseases
(This special issue belongs to the Section Physiology and Pathology)
3D Imaging and Facial Reconstruction
edited by Marios Papadakis
submission deadline 31 Jan 2025 | Viewed by 39 | Submission Open
Keywords: 3D imaging; facial plastic surgery; reconstructive surgery; virtual surgical planning; custom implants; preoperative planning; intraoperative navigation
(This special issue belongs to the Section Medical Research)
Multidisciplinary Approach for Diagnosis and Management of Cardiac Sarcoidosis—the Role of Multi-centre Registry Development
edited by Vasileios Kouranos, Rakesh Sharma and Thomas Luescher
submission deadline 31 Jan 2025 | Viewed by 29 | Submission Open
Keywords: cardiac sarcoidosis; registry; multidisciplinary
(This special issue belongs to the Section Physiology and Pathology)
Ecology and Conservation of Small Mammals: Exploring Biodiversity, Climate Resilience, and Ecosystem Dynamics through Small Mammal Monitoring and Research: 2nd Edition submission deadline 31 Jan 2025 | Viewed by 27 | Submission Open
Keywords: small mammals; biodiversity; indicators; monitoring; assessment; communities
(This special issue belongs to the Section Diversity and Ecology)
Resistance Training in Medicine submission deadline 31 Jan 2025 | Viewed by 26 | Submission Open
Keywords: resistance training; resistance exercise; physical activity; sedentary behavior; strength training; chronic disease; risk factors; obesity; physical health
(This special issue belongs to the Section Epidemiology)
Epidemiology Studies of Cardiovascular Diseases in Older Adults
edited by Nadya Kagansky
submission deadline 31 Jan 2025 | Viewed by 25 | Submission Open
Keywords: cardiovascular diseases in older adults; gerontology; hypertension; hyperlipidemia; diabetes; obesity
(This special issue belongs to the Section Epidemiology)
Research Update on Pancreaticobiliary Endotherapy
edited by Mateusz Jagielski
submission deadline 18 Feb 2025 | Viewed by 44 | Submission Open
Keywords: acute pancreatitis; chronic pancreatitis; pancreatic necrosis; pancreatic pseudocyst; endoscopic retrograde cholangiopancreatography (ERCP); endoscopic ultrasound (EUS); transpapillary drainage; transmural drainage; endoscopic necrosectomy
(This special issue belongs to the Section Medical Research)
Immuno-Pathogenesis Skin Diseases: Novel Molecular Targets and Biomarkers: 2nd Edition submission deadline 20 Feb 2025 | 2 articles | Viewed by 2032 | Submission Open
Keywords: chronic inflammatory skin diseases; immunopathogenesis; inflammatory pathways; molecular target; biomarkers; psoriasis; atopic dermatitis; hidradenitis suppurativa; urticaria; skin cancer
(This special issue belongs to the Section Physiology and Pathology)
Therapeutic Effects of Natural Products on Human Diseases: 2nd Edition
edited by
submission deadline 25 Feb 2025 | Viewed by 156 | Submission Open
Keywords: natural products; natural extracts; cancer; neurodegenerative diseases; immunological disorders; metabolic diseases; oriental medicine; microorganisms; algae; functional foods
(This special issue belongs to the Section Pharmaceutical Science)
Structural Biology of Pathogens and Drug Development
edited by
submission deadline 25 Feb 2025 | Viewed by 6 | Submission Open
Keywords: antiviral and antibacterial medications; emerging infectious diseases; drug-resistant pathogens; structural biology; drug discovery and design; medicinal chemistry; drug screening
(This special issue belongs to the Section Microbiology)
Optogenetics and Light-Induced Processes in Synthetic Biology
edited by
submission deadline 26 Feb 2025 | Viewed by 260 | Submission Open
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Helicobacter pylori
edited by and
submission deadline 28 Feb 2025 | 4 articles | Viewed by 22243 | Submission Open
Keywords: H. Pylori; cancers; antioxidative process; diagnostic methods
(This special issue belongs to the Section Microbiology)
Effects of Environmental Factors on Challenges of Plant Breeding submission deadline 28 Feb 2025 | 4 articles | Viewed by 6304 | Submission Open
Keywords: plant breeding; winter hardiness; sowing time; adaptation to cold/frost; physiology of cold/frost tolerance; snow cover
(This special issue belongs to the Section Plant Science)
Noninvasive Skin Imaging: The Present and the Future in General Dermatology
edited by and
submission deadline 28 Feb 2025 | Viewed by 53 | Submission Open
Keywords: skin imaging; dermatoscopy; dermatology imaging; dermatosurgery; clinical dermatology
(This special issue belongs to the Section Medical Research)
Multi-Omics for Diagnosing Diseases: Bioinformatics Approaches and Integrative Data Analyses submission deadline 28 Feb 2025 | Viewed by 49 | Submission Open
Keywords: bioinformatics; computer hardware; software; and methods; first-/second-/third-generation sequencing; clinical genomics; mendelian diseases; whole-exome sequencing; evolutionary and comparative genomics; whole-genome sequencing; multi-omics; microbiome diseases
(This special issue belongs to the Section Genetics and Genomics)
Gender Medicine: Current Knowledge and Future Perspectives
edited by
submission deadline 28 Feb 2025 | Viewed by 37 | Submission Open
Keywords: gender; gender medicine; LGBTQ + health; health equity in gender medicine; intersectionality; pharmacology; reproductive health; chronic diseases; transgender healthcare; sex-specific healthcare
Clinical Research in Male Reproduction
edited by Andrea Crafa, and Richard Quinton
submission deadline 28 Feb 2025 | Viewed by 33 | Submission Open
Keywords: male infertility; male fertility; male sub-fertility; idiopathic male infertility; male reproduction
(This special issue belongs to the Section Medical Research)
Effects of Exercise on Susceptibility to Environmental and Disease Stressors
edited by Suzanne M. Schneider
submission deadline 28 Feb 2025 | Viewed by 30 | Submission Open
Keywords: aerobic exercise; physical activity; steps per day; cytokines; exerkines; hepatokines; myokines; adipokines; gut– brain axis; immune function; obesity; diabetes; cardiovascular disease; hypertension; osteoporosis; tumor growth; cognitive function; dementia; depression; sleep disorders; hyperthermia; asthma
(This special issue belongs to the Section Physiology and Pathology)
Reconstruction of Bone Defects submission deadline 28 Feb 2025 | Viewed by 27 | Submission Open
Keywords: bone and fracture biomechanics; bone healing; critical size bone defects; fracture non-union; inflammation; joint arthroplasty and fracture osteosynthesis; implant designs; materials proprieties; patient selection; primary and revision settings
(This special issue belongs to the Section Medical Research)
Urinary Microbiome and Genitourinary System Disorders: 2nd Edition submission deadline 28 Feb 2025 | Viewed by 26 | Submission Open
Keywords: microbiome; microbiota; bacteria; 16s-RNA sequencing; bladder; urinary tract infection; urgency; incontinence; lower urinary tract symptoms (LUTS)
(This special issue belongs to the Section Microbiology)
Updates in Genetic Susceptibility to Cancers
edited by Chia-Wen Tsai
submission deadline 28 Feb 2025 | Viewed by 13 | Submission Open
Keywords: cancer genomics; genome-wide association study (GWAS); single nucleotide polymorphism (SNP); genotype-phenotype correlation; prognosis; diagnosis
(This special issue belongs to the Section Medical Research)
Laparoscopy and Treatment. An All-Encompassing Solution for Surgeons
edited by Niculae Iordache and Claudiu-Octavian Ungureanu
submission deadline 5 Mar 2025 | Viewed by 31 | Submission Open
Keywords: oncological; staging laparoscopy; tool; radical surgery; diagnostic
(This special issue belongs to the Section Medical Research)
Interdisciplinarity in Cardiovascular Pathology submission deadline 10 Mar 2025 | Viewed by 7 | Submission Open
Keywords: cardiovascular disease; atherosclerosis; cardio-reno-metabolic syndrome; diabetes; obesity; obstructive pulmonary disease; sleep apnea syndrome; low-grade inflammation
(This special issue belongs to the Section Physiology and Pathology)
Etiology, Prediction and Prognosis of Ischemic Stroke
edited by , and Jiang Li
submission deadline 11 Mar 2025 | 1 articles | Viewed by 1399 | Submission Open
Keywords: ischemic stroke; recurrent stroke; etiology; machine learning; artificial intelligence; subtyping; prediction; prognosis; genetic risk factors; lifestyle factors; environmental factors; biomarkers; cerebrovascular diseases; prevention; treatment strategies
(This special issue belongs to the Section Physiology and Pathology)
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