Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metabolic Health: The Interplay between NAFLD, MAFLD, MASLD and Cardiovascular Disease
edited by and Monika Różycka-Kosmalska
submission deadline 26 Jan 2025 | 1 articles | Viewed by 746 | Submission Open
Keywords: non-alcoholic fatty liver disease (NAFLD); metabolic-dysfunction-associated fatty liver disease (MAFLD); metabolic-dysfunction-associated steatotic liver disease (MASLD); cardiovascular disease (CVD); cardiac arrhythmias; structural heart disease; coronary artery disease; hypertension
(This special issue belongs to the Section Medical Research)
Applications of Molecular Dynamics to Biological Systems
edited by
submission deadline 28 Jan 2025 | Viewed by 69 | Submission Open
Keywords: computer simulation; biophysical modeling; molecular dynamics
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Interdisciplinarity in Cardiovascular Diseases: From Pathophysiology to Diagnosis and Treatment—2nd Edition submission deadline 30 Jan 2025 | 9 articles | Viewed by 11833 | Submission Open
Keywords: interdisciplinary team; cardiovascular diseases; cardiovascular complications; gastro-esophago-enterology and hepatology; metabolic associated steato-hepatitis; gut microbiota; nephrocardiology; pulmonary diseases; rheumatology diseases; endocrinology diseases
(This special issue belongs to the Section Physiology and Pathology)
Retinal Diseases: From Molecular Mechanisms to Therapeutics
edited by
submission deadline 30 Jan 2025 | 5 articles | Viewed by 5473 | Submission Open
Keywords: retinal disease; inflammatory disease; genetic diseases; ocular drug development
(This special issue belongs to the Section Physiology and Pathology)
Advanced Strategies in Fracture Treatments
edited by and Chun-Yu Chen
submission deadline 30 Jan 2025 | 5 articles | Viewed by 3799 | Submission Open
Keywords: state of the art; peri-articular fracture; osteoporotic fracture; fragility fracture; treatment protocols
(This special issue belongs to the Section Medical Research)
Pathogenic Mechanisms, Diagnosis, and Treatment of Hypertension: Insights and Implications
edited by Shengyu Mu and Sankar Devarajan
submission deadline 30 Jan 2025 | 1 articles | Viewed by 1053 | Submission Open
Keywords: hypertension; cardiovascular disease; blood pressure; pathogenesis
(This special issue belongs to the Section Physiology and Pathology)
Acari: Biodiversity, Biogeography and Taxonomy Studies
edited by Pavel B. Klimov
submission deadline 30 Jan 2025 | Viewed by 302 | Submission Open
Keywords: phylogenetics; systematics; evolution and co-evolution; biodiversity; ecology; host associations; role of mites in agriculture and medicine
(This special issue belongs to the Section Animal Science)
Bone Cancer: From Molecular Mechanism to Treatment
edited by and Syuan-Ling Lin
submission deadline 30 Jan 2025 | Viewed by 83 | Submission Open
Keywords: bone cancer; metastasis; angiogenesis; targeted drugs; biomarkers
(This special issue belongs to the Section Medical Research)
Advances in Novel Biomaterials-Based Fertilizing Products and Bio-Fertilizers for Sustainable Agricultural Production submission deadline 31 Jan 2025 | 7 articles | Viewed by 14791 | Submission Open
Keywords: biomaterials and bio-nanomaterials; bio-based hydrogels and polymers; lignocellulosic biomass and its derivatives; sustainable agriculture; biodegradability; stimuli-responsive fertilizer delivery; controlled-release fertilizers; bio-synthesis processes and characterization; control/sustained fertilizer release mechanisms; biofertilizers; plant growth-promoting microbes; fertilizers’ use efficiency; plant physiology; productivity; and quality
(This special issue belongs to the Section Plant Science)
Advances and Applications of Sport Physiology
edited by and
submission deadline 31 Jan 2025 | 5 articles | Viewed by 8119 | Submission Open
Keywords: sports medicine; strength and conditioning; diagnostics; sport injuries; performance analysis
(This special issue belongs to the Section Physiology and Pathology)
Feature Paper in Physiology and Pathology: 2nd Edition
edited by and Eleni Stamellou
submission deadline 31 Jan 2025 | 5 articles | Viewed by 2587 | Submission Open
Keywords: applied physiology; biomechanics; cardiovascular pathobiology; cell physiology; comparative pathology; comparative physiology
(This special issue belongs to the Section Physiology and Pathology)
New Trends in Otorhinolaryngology submission deadline 31 Jan 2025 | 3 articles | Viewed by 2529 | Submission Open
Keywords: head and neck; otolaryngology; hearing loss; speech disorders; swallowing disorders; cancer; microRNA; nose; plastic surgery
(This special issue belongs to the Section Medical Research)
Interaction between Dietary Components and Gut Microbiota: Their Effect on Human and Animal Health submission deadline 31 Jan 2025 | 2 articles | Viewed by 2080 | Submission Open
Keywords: gut microbiota; dietary components; disease prevention and development; probiotic and prebiotic; omics approaches; animals’ gut health
(This special issue belongs to the Section Microbiology)
Feature Papers in Medical Research: 3rd Edition
edited by
submission deadline 31 Jan 2025 | 2 articles | Viewed by 1712 | Submission Open
Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research
(This special issue belongs to the Section Medical Research)
Advancements in Heart Failure Research
edited by Tzu-Hurng Cheng and
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1558 | Submission Open
Keywords: cardiac remodeling; biomarkers; precision medicine; patient-centered care; therapeutic innovations
(This special issue belongs to the Section Medical Research)
Novel Finding in Cancer Genomics
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1463 | Submission Open
Keywords: bladder cancer; prostate cancer; renal cell carcinoma; upper tract urothelial carcinoma
(This special issue belongs to the Section Genetics and Genomics)
Pancreatic Cancer Long Survivals
edited by Francesco Leonardi and
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1010 | Submission Open
Keywords: pancreatic cancer; long survival; outcome; pancreatic adenocarcinoma; long-term survival; surgical resection; chemotherapy; NGS
(This special issue belongs to the Section Physiology and Pathology)
Plant Functional Genomics and Breeding
edited by
submission deadline 31 Jan 2025 | 2 articles | Viewed by 967 | Submission Open
Keywords: functional genomics; biological breeding; gene cloning; molecular network; genetic improvement
(This special issue belongs to the Section Plant Science)
Antioxidants—Key Players in Innovative Pharmaceutical Products and Food Supplements
edited by Bogdan Manolescu, Eliza Oprea and
submission deadline 31 Jan 2025 | Viewed by 564 | Submission Open
Keywords: antioxidants; delivery systems; controlled release; bioavailability; bioactive natural products; food supplements
(This special issue belongs to the Section Pharmaceutical Science)
Resistance Training Is Medicine submission deadline 31 Jan 2025 | 1 articles | Viewed by 508 | Submission Open
Keywords: resistance training; resistance exercise; physical activity; sedentary behavior; strength training; chronic disease; risk factors; obesity; physical health
(This special issue belongs to the Section Epidemiology)
Cardioncology: From Molecular Mechanisms to Advanced Imaging and New Treatments
edited by , Giuseppe Pacileo and
submission deadline 31 Jan 2025 | Viewed by 323 | Submission Open
Keywords: cardiotoxicity; echocardiography; cardiac magnetic resonance; cardiac computed tomography; serum cardiac biomarkers; cancer therapy; arrhythmias; cardiotoxicity treatment
(This special issue belongs to the Section Physiology and Pathology)
Novel Diagnostic and Therapeutic Approaches in Congenital Heart Diseases submission deadline 31 Jan 2025 | Viewed by 284 | Submission Open
Keywords: congenital heart disease; echocardiography; interventional cardiology; multimodal imaging; heart surgery
(This special issue belongs to the Section Medical Research)
Common and Novel Markers of Inflammation and Tissue Damage in Various Pathological Conditions submission deadline 31 Jan 2025 | Viewed by 222 | Submission Open
Keywords: body fluids; cytokines; damage-associated molecular patterns (DAMPS); inflammatory response; injury; markers of inflammation and tissue damage; metalloproteinases; novel markers; pathological conditions; proteasome; tissue damage; tissue repair processes; various diseases
(This special issue belongs to the Section Physiology and Pathology)
Advancements in Postoperative Management of Patients After Surgery
edited by , , and Alessandro Cappellani
submission deadline 31 Jan 2025 | Viewed by 189 | Submission Open
Keywords: surgery; ERAS; postoperative management; recovery; pain
(This special issue belongs to the Section Medical Research)
The Regulation Networks of the Circadian Clock in Plants
edited by
submission deadline 31 Jan 2025 | Viewed by 165 | Submission Open
Keywords: plant circadian; circadian clock; transcriptional; post-transcriptional; epigenetic mechanisms
(This special issue belongs to the Section Plant Science)
Ecology and Conservation of Small Mammals: Exploring Biodiversity, Climate Resilience, and Ecosystem Dynamics through Small Mammal Monitoring and Research: 2nd Edition submission deadline 31 Jan 2025 | Viewed by 133 | Submission Open
Keywords: small mammals; biodiversity; indicators; monitoring; assessment; communities
(This special issue belongs to the Section Diversity and Ecology)
Fertility Preservation and Sterility Treatment
edited by
submission deadline 31 Jan 2025 | Viewed by 131 | Submission Open
Keywords: fertility preservation; oncofertility; cryopreservation; basic research; gonadotoxicity; oocyte cryopreservation; sperm cryopreservation; ovarian tissue transplantation; assisted reproductive technologies
3D Imaging and Facial Reconstruction
edited by Marios Papadakis
submission deadline 31 Jan 2025 | Viewed by 110 | Submission Open
Keywords: 3D imaging; facial plastic surgery; reconstructive surgery; virtual surgical planning; custom implants; preoperative planning; intraoperative navigation
(This special issue belongs to the Section Medical Research)
Epidemiology Studies of Cardiovascular Diseases in Older Adults
edited by Nadya Kagansky
submission deadline 31 Jan 2025 | Viewed by 93 | Submission Open
Keywords: cardiovascular diseases in older adults; gerontology; hypertension; hyperlipidemia; diabetes; obesity
(This special issue belongs to the Section Epidemiology)
Inflammation and Natural Products: 2nd Edition
edited by , and Irene García Domínguez
submission deadline 31 Jan 2025 | Viewed by 73 | Submission Open
Keywords: natural products; inflammation; biological activity; anti-inflammatory activity; antioxidant activity; anticancer potential; terrestrial products; marine products; phytochemistry; pharmacology
(This special issue belongs to the Section Pharmaceutical Science)
The Multifaceted Role of B Cells in the Pathogenesis of Rheumatic Diseases
edited by Achilleas Floudas
submission deadline 31 Jan 2025 | Viewed by 71 | Submission Open
Keywords: B cells; antibodies; arthritis; RNAseq; ACPA; RF; antigen-specific
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Multidisciplinary Approach for Diagnosis and Management of Cardiac Sarcoidosis—the Role of Multi-centre Registry Development
edited by Vasileios Kouranos, Rakesh Sharma, Thomas Luescher and Khattar Rajdeep
submission deadline 31 Jan 2025 | Viewed by 68 | Submission Open
Keywords: cardiac sarcoidosis; registry; multidisciplinary
(This special issue belongs to the Section Physiology and Pathology)
Advancing Nanotechnology in Cancer Theranostics
edited by
submission deadline 31 Jan 2025 | Viewed by 51 | Submission Open
Keywords: nanotechnology; cancer; nanoscale materials; nanoparticles; diagnostic accuracy; therapeutic efficacy; metastasis detection and prediction; targeted drug delivery; personalized cancer therapy
(This special issue belongs to the Section Medical Research)
Molecular Mechanisms and Therapeutic Effects of Drugs in Cancer—2nd Edition submission deadline 14 Feb 2025 | 1 articles | Viewed by 553 | Submission Open
Keywords: cancer; therapy; cancer drug; molecular mechanism; signaling pathways; targeted therapy; in silico drug response studies; innovative cancer treatment
(This special issue belongs to the Section Medical Research)
Innovations in Pathology and Viral Oncology
edited by Luca Roncati
submission deadline 17 Feb 2025 | Viewed by 81 | Submission Open
Keywords: pathology; viral oncology; gynecological oncology; hematological oncology; head and neck tumors; human papilloma virus (HPV); HPV-test; PAP-test; oncoviruses; cancer
(This special issue belongs to the Section Physiology and Pathology)
Research Update on Pancreaticobiliary Endotherapy
edited by Mateusz Jagielski
submission deadline 18 Feb 2025 | Viewed by 100 | Submission Open
Keywords: acute pancreatitis; chronic pancreatitis; pancreatic necrosis; pancreatic pseudocyst; endoscopic retrograde cholangiopancreatography (ERCP); endoscopic ultrasound (EUS); transpapillary drainage; transmural drainage; endoscopic necrosectomy
(This special issue belongs to the Section Medical Research)
Immuno-Pathogenesis Skin Diseases: Novel Molecular Targets and Biomarkers: 2nd Edition submission deadline 20 Feb 2025 | 2 articles | Viewed by 2528 | Submission Open
Keywords: chronic inflammatory skin diseases; immunopathogenesis; inflammatory pathways; molecular target; biomarkers; psoriasis; atopic dermatitis; hidradenitis suppurativa; urticaria; skin cancer
(This special issue belongs to the Section Physiology and Pathology)
Robot-Assisted Surgery: New Trends and Solutions
edited by and Felipe Boff Maegawa
submission deadline 20 Feb 2025 | 2 articles | Viewed by 1878 | Submission Open
Keywords: robotic surgery; minimally invasive abdominal surgery; minimally invasive liver surgery; minimally invasive pancreatic surgery
(This special issue belongs to the Section Medical Research)
Gynecological Endocrinology: From Physiological Mechanisms to Clinical Practice
edited by Ralitsa Robeva
submission deadline 20 Feb 2025 | Viewed by 196 | Submission Open
Keywords: PCOS; hypothalamic amenorrhea; congenital adrenal hyperplasia; hypogonadotropic hypogonadism; premature ovarian insufficiency (POI)
(This special issue belongs to the Section Physiology and Pathology)
Vascular Disease: Etiologic, Diagnostic, Prognostic and Therapeutic Research—2nd Edition submission deadline 21 Feb 2025 | 6 articles | Viewed by 6119 | Submission Open
Keywords: vascular diseases; etiology; diagnosis; prognosis; therapy
(This special issue belongs to the Section Medical Research)
Effects of Physical Training on Youth Athletes' Physical Performance, Health and Well-Being
edited by , and Oliver Gonzalo-Skok
submission deadline 25 Feb 2025 | 4 articles | Viewed by 3599 | Submission Open
Keywords: biological maturation; strength; endurance; speed; sleep; psychosocial; physical activity; conditioning; long-term athlete development; body composition
(This special issue belongs to the Section Physiology and Pathology)
Therapeutic Effects of Natural Products on Human Diseases: 2nd Edition
edited by
submission deadline 25 Feb 2025 | Viewed by 276 | Submission Open
Keywords: natural products; natural extracts; cancer; neurodegenerative diseases; immunological disorders; metabolic diseases; oriental medicine; microorganisms; algae; functional foods
(This special issue belongs to the Section Pharmaceutical Science)
Structural Biology of Pathogens and Drug Development
edited by
submission deadline 25 Feb 2025 | Viewed by 108 | Submission Open
Keywords: antiviral and antibacterial medications; emerging infectious diseases; drug-resistant pathogens; structural biology; drug discovery and design; medicinal chemistry; drug screening
(This special issue belongs to the Section Microbiology)
Pathophysiology, Diagnosis and Treatment of Immune Disease
edited by and Lucia Vietri
submission deadline 26 Feb 2025 | 1 articles | Viewed by 2269 | Submission Open
Keywords: immune disease treatment; autoimmunity; biomarkers; treatment; immunology
(This special issue belongs to the Section Physiology and Pathology)
Optogenetics and Light-Induced Processes in Synthetic Biology
edited by
submission deadline 26 Feb 2025 | Viewed by 322 | Submission Open
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Pathophysiology, Diagnosis, and Treatments of Intestinal Diseases
edited by Amosy Ephreim M’Koma
submission deadline 26 Feb 2025 | Viewed by 100 | Submission Open
Keywords: gastrointestinal disease/disorders; pathophysiology; diagnostics and treatment
(This special issue belongs to the Section Physiology and Pathology)
Carbon and Nitrogen Cycles in Terrestrial Ecosystems
edited by
submission deadline 26 Feb 2025 | Viewed by 37 | Submission Open
Keywords: process-based modeling and machine learning; field experiments and meta-analysis; terrestrial carbon and nitrogen cycles; role of living organisms in biogeochemical cycles
(This special issue belongs to the Section Diversity and Ecology)
Helicobacter pylori
edited by and
submission deadline 28 Feb 2025 | 8 articles | Viewed by 25936 | Submission Open
Keywords: H. Pylori; cancers; antioxidative process; diagnostic methods
(This special issue belongs to the Section Microbiology)
Effects of Environmental Factors on Challenges of Plant Breeding submission deadline 28 Feb 2025 | 5 articles | Viewed by 7816 | Submission Open
Keywords: plant breeding; winter hardiness; sowing time; adaptation to cold/frost; physiology of cold/frost tolerance; snow cover
(This special issue belongs to the Section Plant Science)
Fertility Preservation in Female and Male Benign and Malignant Conditions: 2nd Edition
edited by Arianna D’Angelo, Suman Dadhich and Ali Thwaini
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1472 | Submission Open
Keywords: oncofertility; fertility preservation; cancer; oncology; fertility; egg freezing; embryo freezing; sperm freezing; freezing; IVF; premature ovarian failure; premature ovarian insufficiency; testicular failure; ovarian tissue freezing; PESA; TESE
(This special issue belongs to the Section Reproductive and Developmental Biology)
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