Target Identification of Marine Natural Products

Dear Colleagues,

This issue aims to bring together the latest research and advancements in identifying molecular targets for marine-derived compounds, shedding light on their potential therapeutic applications and mechanisms of action.

Marine organisms have long been recognized as a rich source of bioactive compounds with diverse chemical structures and pharmacological properties. From deep-sea sponges to coastal algae, the oceans harbor a treasure trove of natural products with immense potential for drug discovery and development. However, harnessing the therapeutic potential of marine natural products necessitates a deep understanding of the molecular targets within biological systems. Identifying these targets is crucial for elucidating the underlying mechanisms of action, optimizing drug design, and ultimately translating marine natural products into clinically relevant therapeutics.

This Special Issue welcomes original research articles, reviews, and perspectives covering a wide range of topics related to target identification in marine natural products, including but not limited to innovative approaches and technologies for target identification; mechanistic insights into the biological activities of marine natural products; target identification of marine compounds with therapeutic potential in various disease areas, such as thrombosis, vascular diasorders, cancer, infectious diseases, neurodegenerative disorders, and inflammation; bioinformatics and computational methods for target prediction and validation; case studies highlighting successful target identification and validation processes; and strategies for overcoming challenges in target identification of marine natural products.

For this Special Issue, we encourage researchers from diverse scientific disciplines to contribute their latest findings, reviews, and perspectives to this dynamic and interdisciplinary field to advance our understanding in target identification of marine natural products.

Prof. Dr. Chuanbin Shen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• marine natural products
• target identification and validation
• biomolecular interactions
• molecular therapy
• bioactive compounds targeting membrane proteins or nuclear receptors
• high-throughput screening of bioactive compounds