Cardiac Transplantation: Clinical Outcome, Complications and Follow-Up

Dear Colleagues,

Cardiac transplantation represents the gold-standard treatment for patients with end-stage heart failure as it is associated with improved survival and quality of life in these patients. However, its wider application is limited by the scarce availability of suitable organ donors. The huge discrepancy between the growing number of patients suffering from heart failure and the limited number of donors has led to an increase in the use of left ventricular assist devices as a bridge to transplant therapy. New strategies are required to supplement the donor pool, including the expansion of criteria for acceptance of organ donor, the use of non-heart-beating donors, and the development of optimal preservation and perfusion techniques for the reconditioning of the heart after cardiac arrest. Cardiac transplantation may be complicated by primary graft dysfunction, acute allograft rejection, cardiac allograft vasculopathy, infection, acute and chronic renal failure, solid tumors, and hematological malignancy. This Special Issue in Medicina aims to address the whole spectrum of cardiac transplantation including clinical outcome, diagnostic and treatment of the main complications, and follow-up. Comprehensive reviews, original research (be it basic, translational, or clinical research), interesting case series or case reports, and systematic reviews or meta-analyses providing new insights into cardiac transplantation are welcome.

Dr. Antonella Galeone
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• cardiac transplantation
• primary graft failure
• mechanical circulatory support
• left ventricular assist device
• allograft rejection
• cardiac allograft vasculopathy
• quality of life
• xenotransplantation
• machine perfusion
• donation after circulatory death