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Medicina, Volume 61, Issue 5

2025 May - 173 articles

Cover Story: Despite the widespread success of total knee arthroplasty (TKA), 10–20% of patients are dissatisfied, often due to persistent pain, instability, or unnatural knee motion. Advancements in surgical techniques, alignment philosophies, and implant designs have been introduced to increase the satisfaction rate. Medial stabilized TKA have been developed to better replicate native knee kinematics and improve clinical and functional outcomes. This review provides an overview on the current clinical evidence on two types of medial stabilized TKA implants (medial congruent and medial pivot), focusing on different alignment and soft tissue balancing techniques. View this paper
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Articles (173)

  • Article
  • Open Access
2 Citations
2,475 Views
15 Pages

Background and Objectives: The foramen lacerum (FL), located at the base of the skull, is generally considered the safest anatomical pathway for accessing the internal carotid artery (ICA) and the vidian canal (VC) during surgical procedures. We aime...

  • Article
  • Open Access
5 Citations
2,923 Views
19 Pages

Core Exercise as Non-Pharmacological Strategy for Improving Metabolic Health in Prediabetic Women

  • Nuray Yiğiter,
  • Faruk Akçınar,
  • Yavuz Yasul,
  • Vedat Çınar,
  • Taner Akbulut and
  • Gian Mario Migliaccio

Background and Objectives: Prediabetes (PD) is characterized by impaired glucose metabolism and is associated with an elevated risk of type 2 diabetes and cardiovascular diseases. This study aimed to investigate the effects of an 8-week core exercise...

  • Review
  • Open Access
1 Citations
2,221 Views
10 Pages

Genicular Arteries Embolization for Patients with Osteoarthritis, Their Selection, and Follow-Up Based on MRI Findings

  • Aurelija Domarkienė,
  • Lukas Kalytis,
  • Gytis Kanapienis,
  • Marius Kurminas and
  • Algirdas Edvardas Tamošiūnas

Osteoarthritis (OA) is a leading cause of disability worldwide, with its prevalence rising due to aging populations. Management ranges from conservative treatments such as weight management and pharmacologic therapy to surgical interventions such as...

  • Article
  • Open Access
1 Citations
1,056 Views
11 Pages

Computer Viewing Model for Classification of Erythrocytes Infected with Plasmodium spp. Applied to Malaria Diagnosis Using Optical Microscope

  • Eduardo Rojas,
  • Irene Cartas-Espinel,
  • Priscila Álvarez,
  • Matías Moris,
  • Manuel Salazar,
  • Rodrigo Boguen,
  • Pablo Letelier,
  • Lucia San Martín,
  • Valeria San Martín and
  • Neftalí Guzmán
  • + 1 author

Background and Objectives: Malaria is a disease that can result in a variety of complications. Diagnosis is carried out by an optical microscope and depends on operator experience. The use of artificial intelligence to identify morphological patterns...

  • Article
  • Open Access
1,195 Views
10 Pages

Background and Objectives: The transoral endoscopic thyroidectomy-vestibular approach (TOETVA) and parathyroidectomy-vestibular approach (TOEPVA) are scar-free alternatives to conventional surgery but are classified as clean-contaminated due to the o...

  • Article
  • Open Access
1 Citations
1,744 Views
10 Pages

Trends in Group A Streptococcus Pharyngitis and Co-Infection with Severe Acute Respiratory Syndrome Coronavirus 2: A Retrospective Observational Study

  • Hidenori Takahashi,
  • Yugo Satake,
  • Saori Shimizu,
  • Satomi Fujihara,
  • Syunsuke Takano,
  • Suzuko Fukasawa,
  • Kaeyong Park,
  • Naoya Toba,
  • Takahiko Yano and
  • Masaharu Shinkai
  • + 5 authors

Background and Objectives: Group A Streptococcus (GAS) is a leading cause of acute pharyngitis with seasonal outbreaks. The coronavirus disease 2019 (COVID-19) pandemic significantly altered respiratory infection trends; however, its impact on GAS ph...

  • Review
  • Open Access
1 Citations
3,658 Views
12 Pages

Corticosteroid Use in Musculoskeletal and Neuraxial Interventions: Effects on Glycemic Control

  • Brian Singer,
  • Dovid Chaimovitz,
  • Thomas Bucek,
  • Eli Dayon,
  • Aimee Abbott-Korumi,
  • Moshe Spatz,
  • Tejaswi Makkapati,
  • Hayk Petrosyan and
  • Laurent Delavaux

Effective multidisciplinary pain management involves an in-depth knowledge not only of diagnosis and treatment but of how interventional procedures affect patients across all health domains. One of the most common pharmacological tools utilized in pa...

  • Article
  • Open Access
837 Views
11 Pages

Background and Objectives: Padua (1997) and Bland (2000) have already proposed neurophysiological classification scales for patients with carpal tunnel syndrome (CTS), where the absence of orthodromic sensory response is used as a criterion of a seve...

  • Article
  • Open Access
2,620 Views
13 Pages

Psychometric Properties of the Improved Report of Oslo Trauma Research Centre Questionnaires on Overuse Injuries (OSTRC-O2) and Health Problems (OSTRC-H2)

  • Giulio Leonardi,
  • Giovanni Galeoto,
  • Filippo Maselli,
  • Roberto Napoli,
  • Simone Favaretto,
  • Martina Tomassini,
  • Giuseppe Plebani,
  • Lorenzo Carraro and
  • Domenico Angilecchia

Background and Objectives: The Oslo Sports Trauma Research Centre Overuse Injury Questionnaire (OSTRC-O2) and the Oslo Sports Trauma Research Centre Questionnaire on Health Problems (OSTRC-H2) scales are designed to objectively monitor various overus...

  • Review
  • Open Access
1 Citations
2,737 Views
23 Pages

Splanchnic vein thrombosis (SVT) is a heterogeneous group of disorders affecting the portal, mesenteric, splenic, and hepatic veins. While frequently associated with liver cirrhosis and malignancy, SVT also occurs in non-cirrhotic, non-neoplastic pat...

  • Article
  • Open Access
1 Citations
1,145 Views
11 Pages

Background and Objectives: To examine individual-level sex differences in traditional and non-traditional risk factors and their potential effects on the severity of coronary artery disease (CAD). Materials and Methods: A cross-sectional analysis was...

  • Article
  • Open Access
1 Citations
2,469 Views
16 Pages

Integrating Brain-Computer Interface Systems into Occupational Therapy for Enhanced Independence of Stroke Patients: An Observational Study

  • Erika Endzelytė,
  • Daiva Petruševičienė,
  • Raimondas Kubilius,
  • Sigitas Mingaila,
  • Jolita Rapolienė and
  • Inesa Rimdeikienė

Background and Objectives: Brain-computer interface (BCI) technology is revolutionizing stroke rehabilitation by offering innovative neuroengineering solutions to address neurological deficits. By bypassing peripheral nerves and muscles, BCIs enable...

  • Article
  • Open Access
1,579 Views
13 Pages

Quality of Life, Caregiver Burden, and Symptoms of Depression and Anxiety in Parents of Children with Spinal Muscular Atrophy: A Comparison with Healthy Controls

  • Zehra Koyuncu,
  • Seda Sönmez Kurukaya,
  • Fitnat Uluğ,
  • Tuğçe Damla Dilek,
  • Yılmaz Zindar,
  • Büşra Arslan,
  • Berkay Tayşi,
  • Elif Anaç,
  • Mustafa Balkanas and
  • Sema Saltık
  • + 4 authors

Background: Spinal muscular atrophy (SMA) is a disease that leads to muscle weakness and significantly affects the lives of both patients and caregivers. This study aims to compare quality of life, caregiver burden, symptoms of depression and anxiety...

  • Article
  • Open Access
1 Citations
1,093 Views
16 Pages

Biomarker Patterns and Their Association with Lung Injury in COVID-19 Patients

  • Alexandru Constantin Sîrbu,
  • Anca Daniela Farcaș,
  • Ioana Corina Bocsan,
  • Maria Adriana Neag,
  • Ștefan Cristian Vesa,
  • Șoimița Mihaela Suciu and
  • Anca Dana Buzoianu

Background and Objectives: The study investigates the relationship between accessible biomarkers and the extent of lung damage, assessed with computed tomography (CT) imaging, in patients hospitalized for COVID-19. Materials and Methods: This retrosp...

  • Systematic Review
  • Open Access
4,698 Views
11 Pages

Efficacy and Safety of Nitrous Oxide (N2O) Inhalation Sedation Compared to Other Sedative Agents in Dental Procedures: A Systematic Review with Meta-Analysis

  • Francesca Piccialli,
  • Marco Fiore,
  • Roberto Giurazza,
  • Fabrizio Falso,
  • Vittorio Simeon,
  • Paolo Chiodini,
  • Diana Russo and
  • Luigi Laino

Background and Objectives: Dental procedures can be distressing, particularly for patients who are anxious or uncooperative. In such cases, effective sedation not only facilitates the clinician’s work but also enhances patient comfort and accep...

  • Article
  • Open Access
2,968 Views
10 Pages

Background: This retrospective study evaluated and compared oncological outcomes in patients with localized prostate cancer treated either by laparoscopic radical prostatectomy (LRP) or by external beam radiotherapy (EBRT) combined with androgen depr...

  • Article
  • Open Access
1 Citations
1,830 Views
19 Pages

Aim: This study aimed to investigate the effect of Euthyroid Sick Syndrome (ESS) on non-invasive mechanical ventilation (NIV) failure and in-hospital mortality. We also examined the impact of prolonged low fT3 levels before intensive care unit (ICU)...

  • Article
  • Open Access
2 Citations
1,525 Views
11 Pages

Clinical Effectiveness, Clinical Stability, and Effects on Serum Galectin-7 Levels of Dupilumab and JAK Inhibitors in Moderate-to-Severe Atopic Dermatitis: A Real-World, Single-Center Analysis

  • Akihiro Horie,
  • Tomomitsu Miyagaki,
  • Chikako Hiranuma,
  • Mami Iijima,
  • Yoshiaki Hara,
  • Shinya Oba,
  • Mina Hashimoto,
  • Reina Omori,
  • Tatsuro Okano and
  • Takafumi Kadono

Background and Objectives: Several biologics and oral Janus kinase (JAK) inhibitors have been developed and shown in clinical trials and real-world studies to be effective and safe in moderate-to-severe atopic dermatitis (AD). In this study, we aimed...

  • Article
  • Open Access
968 Views
12 Pages

Clinical and Sociodemographic Characteristics of Patients with Peripheral Facial Paralysis in Medical Rehabilitation: A Comprehensive Description

  • María Navarro-Martínez,
  • Paula Rodríguez-Fernández,
  • Sandra Núñez-Rodríguez and
  • Jerónimo Javier González-Bernal

Background and Objectives: Peripheral facial paralysis (PFP) is a condition with diverse etiologies, requiring multidisciplinary management. This study aimed to describe the sociodemographic, clinical, and functional characteristics of patients with...

  • Review
  • Open Access
1,684 Views
12 Pages

Prostate-Specific Membrane Antigen Positron Emission Tomography (PSMA-PET) in Initial Staging of Prostate Cancer Patients: The Beginning of a New Era

  • Juan Gómez Rivas,
  • Irene de la Parra,
  • Sarelis Infante,
  • Laura Ibañez,
  • Beatriz Gutierrez Hidalgo,
  • María Nieves Cabrera,
  • Javier Puente,
  • Noelia Sanmamed,
  • Luis Enrique Ortega Polledo and
  • Jesús Moreno Sierra
  • + 1 author

Background and Objectives: Prostate cancer (PCa) is a common disease, with a significant number of patients initially diagnosed with locoregional or distant metastases. This is why it is essential to have imaging tests with sufficient sensitivity and...

  • Review
  • Open Access
1 Citations
1,529 Views
9 Pages

Artificial Intelligence and Novel Technologies for the Diagnosis of Upper Tract Urothelial Carcinoma

  • Nikolaos Kostakopoulos,
  • Vasileios Argyropoulos,
  • Themistoklis Bellos,
  • Stamatios Katsimperis and
  • Athanasios Kostakopoulos

Background and Objectives: Upper tract urothelial carcinoma (UTUC) is one of the most underdiagnosed but, at the same time, one of the most lethal cancers. In this review article, we investigated the application of artificial intelligence and novel t...

  • Review
  • Open Access
16 Citations
11,052 Views
26 Pages

Strategies to Reduce Hospital Length of Stay: Evidence and Challenges

  • Rahim Hirani,
  • Dhruba Podder,
  • Olivia Stala,
  • Ryan Mohebpour,
  • Raj K. Tiwari and
  • Mill Etienne

Hospital length of stay (HLOS) is a critical healthcare metric influencing patient outcomes, resource utilization, and healthcare costs. While reducing HLOS can improve hospital efficiency and patient throughput, it also poses risks such as premature...

  • Review
  • Open Access
1 Citations
2,498 Views
10 Pages

Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are increasingly used in patients with type 2 diabetes, chronic kidney disease, and heart failure. However, their safety and efficacy in patients with congenital or surgically altered uro...

  • Systematic Review
  • Open Access
1 Citations
2,998 Views
14 Pages

Comparative Efficacy and Tolerability of Treatments for Erythromelalgia: A Systematic Review

  • Abdullah S. Algarni,
  • Reem M. Alharthi,
  • Shaden O. Alqurashi,
  • Ruba M. Alghanmi,
  • Rimaz R. Aldawsari,
  • Maysaa A. Alghamdi and
  • Ramy Samargandi

Background and Objectives: Erythromelalgia (EM) is an uncommon condition marked by recurring redness, intense burning sensations, and elevated limb warmth. This syndrome can be significantly debilitating, and finding effective treatment options often...

  • Article
  • Open Access
2 Citations
887 Views
11 Pages

Comparison of the Effects of Spinal Anaesthesia on Frontal QRS-T Angle in Term and Post-Term Pregnancies Planned for Elective Caesarean Section: A Prospective Study

  • Ahmet Kaya,
  • Mahmut Alp Karahan,
  • Tugba Bingol Tanriverdi,
  • Alev Esercan,
  • Melike Bostanci Erkmen and
  • Zulkif Tanriverdi

Background and Objectives: Post-term pregnancies are associated with increased risks of perinatal complications. This study aimed to evaluate potential cardiac electrophysiological changes in pregnant women by comparing the QRS duration, interval of...

  • Perspective
  • Open Access
1 Citations
1,103 Views
10 Pages

The Hippocratic principle primum non nocere, or “first, do no harm”, serves as a vital lens through which to re-evaluate modern oncology practices. While recent advances such as immunotherapy, targeted agents, and precision medicine have...

  • Article
  • Open Access
1,012 Views
13 Pages

Background and Objectives: Degenerative cervical myelopathy (DCM), a major subtype of degenerative cervical disorders, presents with diverse sagittal alignment patterns. However, radiography-based phenotyping remains underexplored. This study aimed t...

  • Article
  • Open Access
1,740 Views
12 Pages

The Interplay of Cancer and Hypertension: Rising Mortality and Widening Disparities Across the United States (1999–2023)

  • Ibrahim Ali Nasser,
  • Shereen Asghar,
  • Laraib Masud,
  • Muhammad Ali Hafeez,
  • Sonia Hurjkaliani,
  • Eeshal Zulfiqar,
  • Maryam Shahzad,
  • Husain Ahmed,
  • Shahrukh Khan and
  • Raheel Ahmed
  • + 7 authors

Background and Objectives: Growing evidence suggests a strong relationship between hypertension and cancer, which can increase the risk of poor prognosis. However, data regarding mortality related to cancer and hypertension are limited. Our study aim...

  • Review
  • Open Access
6 Citations
4,997 Views
20 Pages

The Global Burden of Maxillofacial Trauma in Critical Care: A Narrative Review of Epidemiology, Prevention, Economics, and Outcomes

  • Antonino Maniaci,
  • Mario Lentini,
  • Luigi Vaira,
  • Salvatore Lavalle,
  • Salvatore Ronsivalle,
  • Francesca Maria Rubulotta,
  • Lepanto Lentini,
  • Daniele Salvatore Paternò,
  • Cosimo Galletti and
  • Luigi La Via
  • + 2 authors

Background and Objectives: Maxillofacial trauma represents a significant global health challenge with substantial physical, psychological, and socioeconomic consequences. Materials and Methods: This narrative review analyzed 112 articles published be...

  • Article
  • Open Access
2 Citations
1,285 Views
12 Pages

Osteogenic Potential and Bone Matrix Maturity: Comparison of Demineralized Bone Matrix and P15 Polypeptide iFactor® in an In Vitro Study

  • Anell Olivos-Meza,
  • Monica Maribel Mata-Miranda,
  • Marcelo Robles-Rodríguez,
  • Gustavo Jesús Vázquez-Zapién,
  • Melissa Guerrero-Ruiz and
  • Carlos Landa-Solís

Background and Objectives: Demineralized bone matrix (DBM) is a widely used bone graft substitute due to its osteoconductive and osteoinductive properties. However, its efficacy varies due to differences in donor, processing, and storage conditions....

  • Review
  • Open Access
2 Citations
2,664 Views
18 Pages

The Role and Appropriate Selection of Guidewires in Biliopancreatic Endoscopy

  • Daniele Alfieri,
  • Claudia Delogu,
  • Stefano Mazza,
  • Aurelio Mauro,
  • Erica Bartolotta,
  • Alessandro Cappellini,
  • Davide Scalvini,
  • Francesca Torello Viera,
  • Marco Bardone and
  • Andrea Anderloni

Guidewires are indispensable tools in biliopancreatic endoscopy, playing a critical role in facilitating access and enabling the advancement of various devices during interventions such as Endoscopic Retrograde Cholangiopancreatography (ERCP) and End...

  • Article
  • Open Access
3 Citations
1,244 Views
14 Pages

Background and Objectives: Central sensitization (CS) has been identified as a significant factor influencing persistent pain and dissatisfaction following total knee arthroplasty (TKA). However, its effect on unicompartmental knee arthroplasty (UKA)...

  • Review
  • Open Access
4 Citations
11,060 Views
31 Pages

Tuberculosis remains a significant public health challenge globally. The emergence of multidrug-resistant Mycobacterium tuberculosis strains presents one of the biggest hurdles in tuberculosis management. Both first- and second-line tuberculosis drug...

  • Article
  • Open Access
3 Citations
2,630 Views
17 Pages

Trends in Myocardial Infarction Morbidity and Mortality from Ischemic Heart Disease in Middle-Aged Lithuanian Population from 2000 to 2023: Data from Population-Based Kaunas Ischemic Heart Disease Register

  • Ricardas Radisauskas,
  • Lolita Sileikiene,
  • Daina Kranciukaite-Butylkiniene,
  • Sarunas Augustis,
  • Erika Jasukaitiene,
  • Dalia Luksiene,
  • Abdonas Tamosiunas,
  • Karolina Marcinkeviciene,
  • Dalia Virviciute and
  • Gintare Sakalyte
  • + 1 author

Background and Objectives: Over the past decades, various epidemiological analyses have reported a significant decrease in the number of deaths related to cardiovascular diseases (CVDs). Trends in acute myocardial infarction (AMI) morbidity and morta...

  • Article
  • Open Access
1 Citations
1,008 Views
8 Pages

Selective Versus Non-Selective Thoracic Fusion for Adolescent Idiopathic Scoliosis Lenke 1B/1C Curves: Multi-Center Clinical and Radiographic Analysis at 2-Year Follow-Up

  • Yoshinari Miyaoka,
  • Masashi Uehara,
  • Tomohiro Banno,
  • Shoji Seki,
  • Tetsuro Ohba,
  • Hiroki Oba,
  • Shota Ikegami,
  • Terue Hatakenaka,
  • Daisuke Kurogochi and
  • Jun Takahashi
  • + 6 authors

Background and Objectives: This retrospective cohort study compared selective thoracic fusion (STF) and non-STF for adolescent idiopathic scoliosis (AIS) Lenke 1B/1C curves. Although STF is considered an attractive option for patients with a compensa...

  • Review
  • Open Access
9 Citations
5,312 Views
35 Pages

Multimodal Prehabilitation in Major Abdominal Surgery—Rationale, Modalities, Results and Limitations

  • George Andrei Popescu,
  • Dana Galieta Minca,
  • Nader Mugurel Jafal,
  • Cristian Valentin Toma,
  • Sorin Tiberiu Alexandrescu,
  • Radu Virgil Costea and
  • Catalin Vasilescu

Recent evidence revealed that an adequate preoperative physiological reserve is crucial to overcome surgical stress response. Consequently, a new concept, called prehabilitation, emerged, aiming to improve the preoperative functional reserve of patie...

  • Article
  • Open Access
3 Citations
1,831 Views
12 Pages

Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D

  • David Palomar-Albert,
  • Jorge Zamora-Ortiz,
  • Federico Palomar-Llatas,
  • Marta Escudero-Martínez,
  • Alba Naranjo-Cuellar and
  • Maria Isabel Pastor-Orduña

Background and Objectives: Chronic wounds severely impair patients’ quality of life (QoL), impacting physical, emotional, and functional well-being. Understanding the multidimensional effects of treatment is key to implementing effective, patie...

  • Article
  • Open Access
2 Citations
1,060 Views
10 Pages

Retinal Hemorrhages and Long-Term Ocular Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy

  • Emrah Utku Kabataş,
  • Seda Aydoğan,
  • Ahmet Alp Bilgiç,
  • Nurdan Dinlen Fettah,
  • Naciye Kabataş,
  • Dilek Dilli and
  • Ayşegül Zenciroğlu

Background and Objective: This study aims to investigate the clinical significance and risk factors of retinal hemorrhages (RH) and white-centered retinal hemorrhages (Roth spots, RS) in neonates with hypoxic-ischemic encephalopathy (HIE), as well as...

  • Systematic Review
  • Open Access
1,655 Views
18 Pages

Autogenous Periosteal Graft Along with Open Flap Debridement Versus Open Flap Debridement Alone for the Treatment of Grade II Furcation Defect in Chronic Periodontitis Patients: A Systematic Review and Meta-Analysis

  • Swapna A. Mahale,
  • Prasad Dhadse,
  • Sumedha Thosar,
  • Vedant Bhandari,
  • Akhil Patil,
  • Sadatullah Syed,
  • Ranjeet Ajit Bapat,
  • Tanay Chaubal,
  • Sumaiya Zabin Eusufzai and
  • Shahabe Saquib Abullais

Background and Objectives: Periodontal regeneration involves techniques intended at restoring the lost supporting tissue around a periodontally weakened tooth. These regenerative methods frequently utilize periosteal grafts to stimulate the evolvemen...

  • Article
  • Open Access
2 Citations
1,048 Views
13 Pages

Impact of Institutional Monthly Volume of Transcatheter Edge-to-Edge Repair Procedures for Significant Mitral Regurgitation: Evidence from the GIOTTO-VAT Study

  • Nicola Corcione,
  • Paolo Ferraro,
  • Filippo Finizio,
  • Michele Cimmino,
  • Michele Albanese,
  • Alberto Morello,
  • Giuseppe Biondi-Zoccai,
  • Paolo Denti,
  • Antonio Popolo Rubbio and
  • Arturo Giordano
  • + 18 authors

Background and Objectives: Mitral valve transcatheter edge-to-edge repair (TEER) is a widely adopted therapeutic approach for managing significant mitral regurgitation (MR) in high-risk surgical candidates. While procedural safety and efficacy have b...

  • Article
  • Open Access
2 Citations
778 Views
11 Pages

Does Body Mass Index Impact Outcomes in Patients Undergoing Minimally Invasive Mitral Valve Surgery?

  • Mariafrancesca Fiorentino,
  • Elisa Mikus,
  • Diego Sangiorgi,
  • Alberto Tripodi,
  • Simone Calvi,
  • Elena Tenti,
  • Antonino Costantino and
  • Carlo Savini

Background: This study examines the impact of Body Mass Index (BMI) on outcomes after mitral valve surgery via right minithoracotomy, an approach that may reduce wound complications in obese patients. Methods: Between January 2010 and December 2024,...

  • Article
  • Open Access
1,306 Views
12 Pages

Ultrasonography of the Vagus Nerve for ALS Patients: Correlations with Clinical Data and Dysfunction of the Autonomic Nervous System

  • Ovidijus Laucius,
  • Justinas Drūteika,
  • Tadas Vanagas,
  • Renata Balnytė,
  • Andrius Radžiūnas and
  • Antanas Vaitkus

Background and Objectives: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the degeneration of both upper and lower motor neurons, leading to the rapid decline of motor function. In recent years, dysfu...

  • Article
  • Open Access
977 Views
13 Pages

Serial Changes in Vitamin D Status in Patients During Severe Acute Respiratory Distress Syndrome and Extracorporeal Membrane Oxygenation

  • Martina Hermann,
  • Jelena Poslussny,
  • Gernot Gerger,
  • Helmuth Haslacher,
  • Georg Mayrhofer,
  • Verena Eva Tretter,
  • Mathias Maleczek and
  • Cem Ekmekcioglu

Background and Objectives: Therapeutic interventions, such as extracorporeal membrane oxygenation (ECMO) therapy, in patients suffering from severe acute respiratory distress syndrome (ARDS) may reduce their vitamin D levels. Many observational studi...

  • Article
  • Open Access
1 Citations
1,505 Views
14 Pages

Prevalence of Genetic Variants Associated with Atrial Fibrillation Risk in the Asymptomatic Young Adult Population

  • Manoranjani Murugan,
  • Sambandam Ravikumar,
  • Irisappan Ganesh,
  • Yogesh Vetriselvan,
  • Arunagiri Priyadharshini and
  • Vishnu Bhat Ballambattu

Background and Objectives: Atrial fibrillation (AF) is the most common cardiac arrhythmia globally, leading to a high risk of stroke and heart failure. Genetic factors are known to play an essential role in AF risk. However, studies on genetic predis...

  • Review
  • Open Access
1 Citations
1,123 Views
11 Pages

Mpox Infection and Endocrine Health: Bridging the Knowledge Gap

  • Christos Savvidis,
  • Manfredi Rizzo and
  • Ioannis Ilias

Mpox (MPX), caused by the Monkeypox virus (MPXV), is a zoonotic orthopoxvirus infection with increasing global relevance due to sustained human-to-human transmission. While primarily known for cutaneous and systemic involvement, emerging evidence sug...

  • Article
  • Open Access
1,126 Views
12 Pages

Elevated Leukocyte Glucose Index (LGI) Is Associated with Diabetic Ketoacidosis (DKA) Severity and Presence of Microvascular Complications

  • Mircea Cătălin Coșarcă,
  • Raluca Maria Tilinca,
  • Nicolae Alexandru Lazăr,
  • Suzana Vasilica Șincaru,
  • Bogdan Corneliu Bandici,
  • Cosmin Carașca,
  • Ráduly Gergő,
  • Adrian Vasile Mureșan and
  • Mariana Cornelia Tilinca

Background and Objectives: Diabetic ketoacidosis (DKA) represents the most prevalent hyperglycemic emergency and poses a significant life-threatening metabolic risk for individuals with diabetes. The present study examines the predictive role of the...

  • Article
  • Open Access
883 Views
12 Pages

Background and Objectives: This study aimed to evaluate the predictive value of ultrasonographic abdominal muscle thickness and thickening ratios for expiratory muscle strength in SCI patients. Materials and Methods: A case-controlled, cross-sectiona...

  • Article
  • Open Access
763 Views
7 Pages

Optimal Localization of the Foramen Ovale for Transseptal Puncture Using the Vertebral Body Units

  • Dong Hoon Kang,
  • Sung Eun Park,
  • Jong Woo Kim,
  • Seong Ho Moon,
  • Ho Jeong Cha,
  • Jong Hwa Ahn and
  • Joung Hun Byun

Background and Objectives: Although transesophageal or intracardiac echocardiography and radiofrequency needles are employed to guide transseptal puncture, their routine utilization is associated with substantial expense. No reports have analyzed the...

  • Systematic Review
  • Open Access
2 Citations
1,563 Views
15 Pages

Beyond Diagnosis: Exploring Residual Autonomy in Dementia Through a Systematic Review

  • Anna Anselmo,
  • Francesco Corallo,
  • Maria Pagano,
  • Davide Cardile,
  • Angela Marra,
  • Giuseppa Maresca,
  • Rosaria De Luca,
  • Antonella Alagna,
  • Angelo Quartarone and
  • Irene Cappadona
  • + 1 author

Background and Objectives: The connection between cognitive decline and autonomy represents a complex and multifactorial area of research. Cognitive decline manifests as a progressive impairment of higher mental functions and is typical of neurodegen...

  • Article
  • Open Access
2 Citations
2,547 Views
14 Pages

Platelet-Rich Plasma Provides Superior Clinical Outcomes Without Radiologic Differences in Lateral Epicondylitis: Randomized Controlled Trial

  • Taha Kizilkurt,
  • Ahmet Serhat Aydin,
  • Taha Furkan Yagci,
  • Ali Ersen,
  • Celal Caner Ercan and
  • Artür Salmaslioglu

Background and Objectives: Lateral epicondylitis, commonly known as tennis elbow, is a prevalent condition characterized by pain and tenderness over the lateral epicondyle. Various treatment options, including corticosteroids, platelet-rich plasma (P...

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Medicina - ISSN 1648-9144