Multiple Sclerosis and Related Disorders: Theory, Methods and Applications
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Neurology".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 20
Special Issue Editors
Interests: multiple sclerosis; neuroepidemiology; cerebrospinal fluid; blood–cerebrospinal fluid barrier; neuroinflammation; gut–brain axis; biomarkers
2. Interdepartmental Research Center for the Study of Multiple Sclerosis and Inflammatory and Degenerative Diseases of the Nervous System, University of Ferrara, 44121 Ferrara, Italy
Interests: multiple sclerosis; neuroepidemiology; cerebrospinal fluid; blood–cerebrospinal fluid barrier; neuroinflammation; gut–brain axis; biomarkers
Special Issue Information
Dear Colleagues,
Multiple sclerosis (MS) and related disorders are among the most complex and debilitating conditions in neurology, affecting millions worldwide. These chronic, immune-mediated diseases target the central nervous system, leading to neurodegeneration and progressive disability, thus significantly impacting patients' quality of life.
In recent decades, advances in neuroimaging, biomarker discovery, and therapeutic strategies have reshaped the landscape of diagnosis, clinical management, and treatment. Despite recent advancements, critical gaps remain, including the need for reliable biomarkers for early diagnosis, the optimization of individualized therapeutic strategies, and the implementation of innovative rehabilitation techniques.
To address these challenges, an interdisciplinary approach that integrates basic science, novel methodologies, and clinical applications is essential. Additionally, the increasing availability of big data and artificial intelligence (AI) presents new opportunities to revolutionize MS research and management, yet their full potential remains to be fully explored.
This Special Issue aims to bring together cutting-edge research that enhances our understanding of MS and related disorders. We seek contributions that not only deepen our knowledge of disease mechanisms but also propose novel diagnostic, therapeutic, and management strategies that can improve patient outcomes.
We invite researchers and clinicians to contribute original studies, reviews, and methodological papers that advance our understanding of MS and related conditions. Studies incorporating interdisciplinary approaches, large-scale data analysis, and novel therapeutic paradigms are particularly encouraged. Topics of interest may include but are not limited to emerging theories on MS etiology and disease progression; advances in imaging and biomarker discovery; novel therapeutic strategies, including immunomodulation and neuroprotection; machine learning and AI applications in MS diagnosis and prognosis; personalized medicine; and patient-centered care approaches.
Prof. Dr. Maura Pugliatti
Guest Editor
Dr. Caterina Ferri
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- multiple sclerosis
- biomarkers
- neurodegeneration
- neuroimaging
- disease-modifying treatments
- artificial intelligence
- telemedicine
- digital therapeutics
- personalized medicine
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