The Role of Metabolic Syndrome and Insulin Resistance in Cardiovascular and Cerebrovascular Dysfunction
A special issue of Medicina (ISSN 1648-9144).
Deadline for manuscript submissions: closed (30 April 2019) | Viewed by 10103
Special Issue Editor
Interests: metabolic syndrome (MetS); obesity; stroke; cardiac, cerebro and vascular function; exercise
Special Issue Information
Dear Colleagues,
There has been an explosion in the number of individuals with metabolic disturbances, resulting in a global epidemic of metabolic syndrome and insulin resistance that shows no signs of slowing. The presence of metabolic syndrome and insulin resistance affects multiple organ beds (heart, vasculature, brain, kidney, etc.) and has clinically very significant consequences, increasing cardiovascular and cerebrovascular risk. Our basic understanding of the processes by which metabolic disease affects cardiovascular and cerebrovascular structure and function remain incomplete. For example, what roles do oxidative stress, inflammation, and their interactions play in the pathogenesis of vascular disease? In light of such questions, the purpose of this Special Issue will be to highlight the important pathways leading to cardio and cerebrovascular dysfunction related to metabolic syndrome and insulin resistance, as well as to discuss potential therapeutic approaches to ameliorate or reduce the risk of CV dysfunction.
Prof. Dr. Paul Chantler
Guest Editor
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Keywords
- cardiovascular
- cerebrovascular
- inflammation
- oxidative stress
- adipose tissue
- exercise
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