Infections in Kidney Transplantation
A special issue of Medicina (ISSN 1648-9144).
Deadline for manuscript submissions: closed (31 August 2019) | Viewed by 3118
Special Issue Editor
Special Issue Information
Dear Colleagues,
Kidney transplantation remains as the treatment of choice for many patients with end-stage kidney disease. Patient and graft survival have improved, mainly due to advances in immunosuppression regimens and antimicrobial prophylaxis.However, infection is the second most common cause of death with a functioning graft in renal transplant recipients (RTRs). Thus, prevention as well as early diagnosis and management are critical to improving patient and graft survival. Donor and recipient screening are essential to optimize both pre- and post-transplant preventative strategies, including vaccination. Improved diagnostics tools and their increased application in routine care now allow for specific microbiological diagnoses to better target therapy. The increasing availability of directly acting anti-viral (DAA) agents for hepatitis C treatment is allowing for the expansion of the donor pool and increasing recipient eligibility. Increasing Gram-negative resistance remains a challenge, particularly for urinary tract infections in RTRs. The role of the microbiome and individualized care are being increasingly recognized. In this Issue, we will provide an update on the prevention, diagnosis, and management of common infections in RTRs and provide some insights into future directions and emerging trends in the area of infections in RTRs.
Dr. Orla Morrissey
Guest Editor
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Keywords
- kidney transplantation
- prophylaxis
- hepatitis C
- cytomegalovirus
- BK virus
- Enterobacteriaceae
- resistance
- fungus
- pneumocystis
- microbiome
- whole-genome sequencing