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Medicina
Special Issues
Research Progress of Surgical Oncology
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Research Progress of Surgical Oncology

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Oncology".

Deadline for manuscript submissions: closed (20 August 2022) | Viewed by 2319

Special Issue Editor

Dr. Nicolae Bacalbaşa

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: oncogynecology; hepato-biliopancreatic surgery; digestive oncological surgery; personalized medicine

Special Issue Information

Dear Colleagues,

As cancer and information regarding neoplastic process genesis continued to evolve in the last century, a similar process was reported in the field of cancer therapy, surgery remaining in a significant number of cases the cornerstone for achieving long-term survival. Meanwhile, in the last decade, the concept of personalized medicine developed, increasing in this way the chances of improving long-term outcomes. The aim of this Special Issue is to focus on the most recently reported technologies in the field of surgical oncology which are expected to improve the oncological outcomes of these cases. Special attention will be paid to the field of gynecologic oncology and hepato-biliopancreatic surgery.

Dr. Nicolae Bacalbaşa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gynecologic oncology
  • pancreatic resection
  • hepatic resection
  • intraperitoneal chemotherapy
  • extended pelvic resections
  • upper abdominal resections

Published Papers (1 paper)

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12 pages, 1129 KiB  
Systematic Review
Clinicopathological Significances of Positive Surgical Resection Margin after Radical Prostatectomy for Prostatic Cancers: A Meta-Analysis
by Minseok Kim, Daeseon Yoo, Jungsoo Pyo and Wonjin Cho
Medicina 2022, 58(9), 1251; https://doi.org/10.3390/medicina58091251 - 9 Sep 2022
Cited by 11 | Viewed by 2095
Abstract
Background and Objectives: This study aims to elucidate the positive rate and the clinicopathological significance of surgical margin after radical prostatectomy (RP) through a meta-analysis. Materials and Methods: This meta-analysis finally used 59 studies, including the information about the positive surgical [...] Read more.
Background and Objectives: This study aims to elucidate the positive rate and the clinicopathological significance of surgical margin after radical prostatectomy (RP) through a meta-analysis. Materials and Methods: This meta-analysis finally used 59 studies, including the information about the positive surgical margin (PSM) and those clinicopathological significances after RP. The subgroup analysis for the estimated rates of PSM was evaluated based on types of surgery, grade groups, and pathological tumor (pT) stages. We compared the clinicopathological correlations between positive and negative surgical margins (NSM). Results: The estimated PSM rate was 25.3% after RP (95% confidence interval [CI] 21.9–29.0%). The PSM rates were 26.0% (95% CI 21.5–31.1%) 28.0% (95% CI 20.2–37.5%) in robot-assisted RP and nerve-sparing RP, respectively. The PSM rate was significantly higher in high-grade groups than in low-grade groups. In addition, the higher pT stage subgroup had a high PSM rate compared to the lower pT stage subgroups. Patients with PSM showed significantly high PSA levels, frequent lymphovascular invasion, lymph node metastasis, and extraprostatic extension. Biochemical recurrences (BCRs) were 28.5% (95% CI 21.4–36.9%) and 11.8% (95% CI 8.1–16.9%) in PSM and NSM subgroups, respectively. Patients with PSM showed worse BCR-free survival than those with NSM (hazard ratio 2.368, 95% CI 2.043–2.744%). Conclusions: Our results showed that PSM was significantly correlated with worse clinicopathological characteristics and biochemical recurrence-free survival. Among the results in preoperative evaluations, grade group and tumor stage are useful for the prediction of PSM. Full article
(This article belongs to the Special Issue Research Progress of Surgical Oncology)
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