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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Lung Cancer Diagnosis and Treatment

edited by

Roberto G. Carbone

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2143 | Submission Open

Keywords: lung cancer mechanism; diagnosis; treatment; biology molecular; imaging; surgery

(This special issue belongs to the Section Pulmonology)

Advances in Facial Plastic and Aesthetic Surgery

edited by

Gennaro D'Orsi

and Benedetto Longo

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1975 | Submission Open

Keywords: face; oral reconstruction; aesthetic surgery; microsurgery; facial surgery

(This special issue belongs to the Section Surgery)

Updates on Caries Management in the Primary and Permanent Dentition: 2nd Edition

edited by

Julian Schmoeckel

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1790 | Submission Open

Keywords: dental caries; treatment; caries management; children; adults; prevention; minimal-invasive

(This special issue belongs to the Section Dentistry and Oral Health)

Current Trends in Breast Reconstructive Surgery

edited by

Daniele Fusario

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1621 | Submission Open

Keywords: breast reconstruction; breast cancer; oncoplastic; alloplastic breast reconstruction; autologous breast reconstruction; outcomes; complications; patient satisfaction

(This special issue belongs to the Section Surgery)

Oral–Systemic Link: Biomarkers, Inflammation, and Disease Cross-Talk

edited by Ana Glavina and

Antonija Tadin

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1537 | Submission Open

Keywords: oral–systemic connection; periodontal disease; inflammatory biomarkers; systemic inflammation; oral microbiome; disease cross-talk; cardiovascular diseases; diabetes mellitus

(This special issue belongs to the Section Dentistry and Oral Health)

Obstructive Sleep Apnea: New Insights and Future Directions

edited by

Cheng-Jung Wu

Ming-Shao Tsai

and

Wen-Te Liu

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1400 | Submission Open

Keywords: obstructive sleep apnea; sleep surgery; precision medicine; artificial intelligence; drug-induced sleep endoscopy (DISE); pharmacotherapy; upper airway stimulation; pediatric sleep apnea; phenotypes

(This special issue belongs to the Section Pulmonology)

The Challenges and Prospects in Clinical Cardiology and Angiology: 2nd Edition

edited by Vincenzo Zaccone and

Giulio Francesco Romiti

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1339 | Submission Open

Keywords: cardiology; angiology; cardiovascular diseases; vascular health; diagnostic techniques; treatment strategies; translational research

(This special issue belongs to the Section Cardiology)

Physiotherapy in Musculoskeletal Pain: Assessment and Management—2nd Edition

edited by Mónica Grande-Alonso and

Ferran Cuenca-Martínez

submission deadline 30 Sep 2026 | 1 articles | Viewed by 967 | Submission Open

Keywords: musculoskeletal pain; sensorimotor factors; therapeutic exercise; motor imagery; new technologies; chronic pain; therapeutic education; manual therapy; rehabilitation; functional evaluation

(This special issue belongs to the Section Orthopedics)

Pathogenesis of Periodontitis: Mechanisms and Clinical Applications

edited by Francesco Spadari,

Matteo Pellegrini

and

Federica Pulicari

submission deadline 30 Sep 2026 | 1 articles | Viewed by 831 | Submission Open

Keywords: microbiome; biomarkers; inflammation; systemic health; periodontal treatment

(This special issue belongs to the Section Dentistry and Oral Health)

Advances in the Diagnosis and Treatment of Cutaneous Melanoma

edited by

Konstantinos Seretis

and Nikolaos Bounas

submission deadline 30 Sep 2026 | 1 articles | Viewed by 715 | Submission Open

Keywords: cutaneous melanoma; early diagnosis; immunotherapy; targeted therapy; molecular biomarkers; precision medicine; surgical management; sentinel lymph node biopsy; dermoscopy; melanoma prognosis

(This special issue belongs to the Section Dermatology)

Oral and Maxillofacial Surgery: From Diagnosis to Treatment

edited by Frank Wilde and Andreas Sakkas

submission deadline 1 Oct 2026 | 1 articles | Viewed by 1471 | Submission Open

Keywords: oral and maxillofacial surgery; clinical diagnosis; maxillofacial trauma; odontogenic infections; orthognathic surgery; reconstructive surgery; temporomandibular disorders; virtual surgical planning; artificial intelligence; patient-specific implants

(This special issue belongs to the Section Dentistry and Oral Health)

Total Hip Arthroplasty: New Perspectives on Primary and Revision Implants

edited by

Francesco Castagnini

and

Stefano Lucchini

submission deadline 1 Oct 2026 | 1 articles | Viewed by 1122 | Submission Open

Keywords: total hip arthroplasty; primary hip implants; revision hip surgery; hip reconstruction surgical approaches; hip revision components; complex hip reconstruction

(This special issue belongs to the Section Orthopedics)

Precision and Regenerative Interventional Pain Medicine: Imaging-Guided, Neuromodulatory and Minimally Invasive Advances

edited by Giuliano Lo Bianco,

Alaa Abd-Elsayed

and Leonardo Kapural

submission deadline 1 Oct 2026 | 2 articles | Viewed by 1105 | Submission Open

Keywords: interventional pain medicine; imaging-guided procedures; neuromodulation; regenerative medicine; pulsed radiofrequency; cryoanalgesia; spinal cord stimulation; chronic pain; precision medicine; ultrasound-guided interventions

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Recent Advances in Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia

edited by

Apostolos Apostolidis

and Efstathios Papaefstathiou

submission deadline 5 Oct 2026 | 3 articles | Viewed by 7221 | Submission Open

Keywords: LUTS; BPH; minimally invasive treatment; digital health tools; biomarkers; microbiome

(This special issue belongs to the Section Urology & Nephrology)

Vitreoretinal Diseases: From Pathophysiology to Therapeutics

edited by Evita Evangelia Christou and Petros Petrou

submission deadline 10 Oct 2026 | Viewed by 351 | Submission Open

Keywords: retina; vitreous; inherited disorders; gene therapy; vitrectomy; scleral buckle; imaging

(This special issue belongs to the Section Ophthalmology)

Advances in Rheumatic and Musculoskeletal Diseases and Health Promotion, 2nd Edition

edited by

Kyoung Kim

and

Do-youn Lee

submission deadline 10 Oct 2026 | Viewed by 210 | Submission Open

Keywords: rheumatic disease; osteoarthritis; rheumatoid arthritis; ankylosing spondylitis; systemic lupus erythematosus; musculoskeletal disorders; sarcopenia; osteoporosis; health promotion; epidemiology; rehabilitation; physical function; functional performance; aging; prevention

(This special issue belongs to the Section Hematology and Immunology)

Early Diagnosis and Management of Glioma

edited by Maurizio Iacoangeli and

Denis Aiudi

submission deadline 15 Oct 2026 | 6 articles | Viewed by 15842 | Submission Open

Keywords: glioma; glioblastoma; neuroimaging; neuro-oncology; early diagnosis; modern technologies; neurosurgery; tumor biology; early therapy; new therapies

(This special issue belongs to the Section Oncology)

Global Perspectives on Sepsis: Epidemiology, Awareness and Treatment Strategies

edited by Alice Dragoescu

submission deadline 15 Oct 2026 | 6 articles | Viewed by 15656 | Submission Open

Keywords: sepsis; global health; treatment strategies; early diagnosis; personalized medicine; immunopathology; awareness campaigns

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Updates on Risk Factors, Prevention and Treatment of Knee Disease

edited by

Giuseppe Solarino

Giuseppe Maccagnano

and

Michele Coviello

submission deadline 15 Oct 2026 | 3 articles | Viewed by 14619 | Submission Open

Keywords: sports medicine; trauma; degenerative; regenerative; rehabilitation; prevention

(This special issue belongs to the Section Orthopedics)

Abdominal Surgery: Innovative Techniques and Challenges

edited by

Tania Triantafyllou

and

Athanasios Pantelis

submission deadline 15 Oct 2026 | 8 articles | Viewed by 7663 | Submission Open

Keywords: minimally invasive surgery; abdominal surgery; surgical innovation; laparoscopy; robotic surgery; embedded systems; image-guided surgery

(This special issue belongs to the Section Surgery)

Clinical Ophthalmology: Current Status and Future Challenges

edited by

Theodora Papamitsou

, Athanasios Karamitsos and

Sofia Karachrysafi

submission deadline 15 Oct 2026 | 3 articles | Viewed by 4817 | Submission Open

Keywords: clinical ophthalmology; ophthalmic pharmacology; biomarkers in eye diseases; ocular diagnostics; AI in ophthalmology; minimally invasive eye surgery; retinal diseases; gene therapy in ophthalmology; surgical innovations in ophthalmology; regenerative medicine for eye diseases

(This special issue belongs to the Section Ophthalmology)

Hematologic Malignancies: Diagnosis, Prognosis and Management

edited by Ádám Jona and

Zsófia Miltényi

submission deadline 15 Oct 2026 | 2 articles | Viewed by 3094 | Submission Open

Keywords: malignant lymphoma; treatment; prognostication; stem cell transplantation; cellular therapy

(This special issue belongs to the Section Oncology)

Updates on Refractive Surgery

edited by Matteo Posarelli and Antonio Leccisotti

submission deadline 15 Oct 2026 | Viewed by 198 | Submission Open

Keywords: lasik; refractive surgery; klex; multifocal IOL; laser vision correction; extended depth of focus IOL

(This special issue belongs to the Section Ophthalmology)

Advances in Digital Technologies for Modern Joint Arthroplasty

edited by Tommaso Bonanzinga and

Alberto Favaro

submission deadline 15 Oct 2026 | Viewed by 173 | Submission Open

Keywords: joint arthroplasty; digital technologies; smart technologies; artificial intelligence; pre-operative planning

(This special issue belongs to the Section Orthopedics)

Diagnosis and Treatment of Urologic Oncology

edited by

Juan Gómez Rivas

and Jesús Moreno Sierra

submission deadline 20 Oct 2026 | 6 articles | Viewed by 12006 | Submission Open

Keywords: bladder cancer; kidney cancer; personalized medicine; prostate cancer; robotic surgery; targeted therapy; testicular cancer

(This special issue belongs to the Section Urology & Nephrology)

Novel Insights in Laparoscopic Surgery of Colorectal Carcinoma

edited by

Stylianos A. Kapiris

submission deadline 20 Oct 2026 | 3 articles | Viewed by 5712 | Submission Open

Keywords: laparoscopic surgery; colorectal cancer; icg; newer technologies

(This special issue belongs to the Section Oncology)

Recent Trends in Physical Therapy for Musculoskeletal Disorders

edited by

Carlos Romero-Morales

and Ángel González-De-La-Flor

submission deadline 20 Oct 2026 | 3 articles | Viewed by 3553 | Submission Open

Keywords: musculoskeletal disorders; physical therapy; rehabilitation; manual therapy; exercise prescription; movement analysis

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

New Advances and Challenges in Plastic Surgery

edited by

Alberto Bolletta

Emanuele Cigna

and Mirco Pozzi

submission deadline 20 Oct 2026 | 1 articles | Viewed by 2158 | Submission Open

Keywords: plastic surgery innovations; reconstructive techniques; aesthetic surgery advances; microsurgery and super-microsurgery; regenerative and digital technologies

(This special issue belongs to the Section Surgery)

New Insights into Breast Cancer Multidisciplinary Care

edited by Alexandru E. Eniu and

Nicoleta Zenovia Antone

submission deadline 20 Oct 2026 | 1 articles | Viewed by 807 | Submission Open

Keywords: breast cancer; personalized medicine; multidisciplinary treatement; patient's clinical; pathway

(This special issue belongs to the Section Oncology)

Advancements and Innovations in Dental Implantology

edited by

Roberta Gasparro

and

Adina Simona Coșarcă

submission deadline 20 Oct 2026 | Viewed by 631 | Submission Open

Keywords: bone augmentation; dental implants; tilted implants; preimplant reconstructive surgery

(This special issue belongs to the Section Dentistry and Oral Health)

Diabetes and Obesity: Innovations in Mechanisms, Diagnostics, and Patient Care

edited by Malgorzata Mysliwiec and

Anna Wołoszyn-Durkiewicz

submission deadline 20 Oct 2026 | 1 articles | Viewed by 615 | Submission Open

Keywords: diabetes; obesity; diagnosis; patient care; endocrinology

(This special issue belongs to the Section Endocrinology)

Asthma Exacerbations and Respiratory Management

edited by

Antonio Matías Esquìnas

submission deadline 20 Oct 2026 | Viewed by 310 | Submission Open

Keywords: acute asthma exacerbations; severe asthma; immunotherapy; non-invasive ventilation; high-flow nasal oxygen therapy; intensive care; respiratory failure; aerosol therapy

(This special issue belongs to the Section Pulmonology)

Cancer Care at the End of Life: Balancing Disease-Directed Treatment, Palliative Care, and Symptom-Oriented Approaches

edited by

Gudrun Kreye

Josef Singer

and

Nguyen-Son Le

submission deadline 20 Oct 2026 | Viewed by 249 | Submission Open

Keywords: end-stage cancer; overtreatment; end-of-life care; symptom control; comfort care; quality of life; intensive care; palliative care; shared decision-making

(This special issue belongs to the Section Oncology)

Transforming Liver Transplantation: Cutting-Edge Surgical Approaches and Clinical Care

edited by

Shekhar Gogna

submission deadline 20 Oct 2026 | Viewed by 207 | Submission Open

Keywords: liver transplantation; machine perfusion; organ preservation; donor expansion; immunosuppression; perioperative management; surgical innovation; transplant oncology

(This special issue belongs to the Section Gastroenterology & Hepatology)

Thyroid Cancer—Recent Advances and Future Directions

edited by Albertas Daukša and

Dalia Daukšienė

submission deadline 20 Oct 2026 | Viewed by 115 | Submission Open

Keywords: thyroid cancer; epigenetic; genetic mutations; DNA methylation; non-coding RNAs; prognosis and risk stratification; therapies; kinase inhibitors

(This special issue belongs to the Section Endocrinology)

Interventional Radiology and Imaging in Cancer Diagnosis

edited by

Katarzyna Skrobisz

and Michal Studniarek

submission deadline 25 Oct 2026 | 7 articles | Viewed by 6065 | Submission Open

Keywords: oncologic imaging; image-guided biopsy; advanced MRI techniques; genitourinary imaging; active surveillance imaging; minimally invasive biopsy; radiology in surgical planning; radiologic–pathologic correlation; clinical radiology

(This special issue belongs to the Section Oncology)

Clinical Advances and Challenges in the Treatment of Malocclusions and Temporomandibular Disorders

edited by

Alessandro Nota

Simona Tecco

and

Laura Pittari

submission deadline 25 Oct 2026 | 3 articles | Viewed by 3538 | Submission Open

Keywords: TMD; orthodontics; digital dentistry; mandibular kinematics

(This special issue belongs to the Section Dentistry and Oral Health)

Evaluation, Management, and Outcomes in Perioperative Medicine

edited by Yale Tung-Chen and

Francisco Javier García Sánchez

submission deadline 25 Oct 2026 | 3 articles | Viewed by 3321 | Submission Open

Keywords: perioperative medicine; surgical outcomes; prehabilitation; risk stratification; patient optimization; enhanced recovery; multimorbidity; postoperative complications; functional recovery; patient-centered care

(This special issue belongs to the Section Surgery)

Emerging Trends in Immunodermatology and Autoimmune Skin Disorders

edited by

Giovanni Damiani

and Magdalena Spałkowska

submission deadline 25 Oct 2026 | 1 articles | Viewed by 2115 | Submission Open

Keywords: autoimmune skin disorders; cutaneous lupus erythematosus; systemic lupus erythematosus; autoantibodies; systemic sclerosis; dermatomyositis; vitiligo; pemphigus; pemphigoid

(This special issue belongs to the Section Dermatology)

Innovations in Cancer Radiation Therapy

edited by

Elona Juozaitytė

and Erika Korobeinikova

submission deadline 25 Oct 2026 | 1 articles | Viewed by 880 | Submission Open

Keywords: radiation oncology; cancer radiotherapy; adaptive radiotherapy; stereotactic radiotherapy; proton therapy; MRI-guided radiotherapy; precision oncology; artificial intelligence

(This special issue belongs to the Section Oncology)

Progress in Total Knee Arthroplasty

edited by Pierangelo Za and

Giuseppe Papalia

submission deadline 25 Oct 2026 | 1 articles | Viewed by 690 | Submission Open

Keywords: total knee replacement; mechanical alignment; kinematic alignment; functional alignment; robot-assisted surgery; computer navigation; implant design; personalized arthroplasty; rehabilitation

(This special issue belongs to the Section Orthopedics)

Contemporany Advances in Diagnosis and Therapeutic Management in Head and Neck Cancer

edited by Federico Bolognesi,

Giovanni Salzano

and

Danilo Di Giorgio

submission deadline 25 Oct 2026 | 1 articles | Viewed by 528 | Submission Open

Keywords: head and neck cancer; oral cavity squamous cell carcinoma; diagnosis; surgery; complications; neck dissection; microsurgical reconstruction; facial paralysis; radiotherapy; immunotherapy; prognostic factors; oncologic outcomes

(This special issue belongs to the Section Oncology)

Innovate to Prevent: Pathophysiology, Personalized Care and Future of Preeclampsia Management

edited by

Chitkasaem Suwanrath

submission deadline 25 Oct 2026 | Viewed by 341 | Submission Open

Keywords: preeclampsia; pregnancy-induced hypertension; placental insufficiency; angiogenic factors; biomarkers; early diagnosis; risk assessment; aspirin; precision medicine; maternal health

(This special issue belongs to the Section Obstetrics and Gynecology)

Traumatic Brain Injury (TBI): Symptoms, Diagnosis and Treatment

edited by Nasim Ahmed

submission deadline 25 Oct 2026 | Viewed by 257 | Submission Open

Keywords: traumatic brain injury; biomarker; prognostication; short term outcomes; long-term outcomes; neuroimaging; acute management; rehabilitation; neuroinflammation; secondary brain injury; functional recovery

(This special issue belongs to the Section Neurology)

Recent Advances in Acute Pancreatitis: Diagnosis, Treatment, and Future Perspectives

edited by

Manuela Mastronardi

, Alan Biloslavo and Antonio La Greca

submission deadline 25 Oct 2026 | Viewed by 252 | Submission Open

Keywords: acute pancreatitis; minimally invasive management; biomarkers; artificial intelligence

(This special issue belongs to the Section Gastroenterology & Hepatology)

Updates in Anterior Segment Eye Research

edited by

Mayank A. Nanavaty

submission deadline 25 Oct 2026 | Viewed by 162 | Submission Open

Keywords: anterior segment; cornea; cataract surgery; refractive surgery; ocular imaging; intraocular lenses; corneal transplantation; ocular surface disease; precision medicine; clinical innovation

(This special issue belongs to the Section Ophthalmology)

New Strategies for the Diagnosis and Treatment of Rheumatic and Musculoskeletal Diseases: 2nd Edition

edited by

Elena Amaricai

and

Carmen Delia Nistor-Cseppento

submission deadline 26 Oct 2026 | 1 articles | Viewed by 760 | Submission Open

Keywords: osteoarthritis; inflammatory rheumatic diseases; osteoporosis; low back pain; physical medicine; rehabilitation; disability; quality of life

(This special issue belongs to the Section Hematology and Immunology)

Retinopathy: From Basic Research to Clinical Practice

edited by

Elena Pacella

and

Mariaelena Malvasi

submission deadline 26 Oct 2026 | Viewed by 242 | Submission Open

Keywords: retinopathy; oxidative stress; retinal hypoxia; ischemic retinal damage; choroidal hypoperfusion; microvascular dysfunction; retinal biomarkers; optical coherence tomography (OCT); systemic vascular disease; optical coherence tomography angiography (OCTA)

(This special issue belongs to the Section Ophthalmology)

Implant Dentistry: Current Practices and Future Direction

edited by Vincent Bennani and Arthi Veerasamy

submission deadline 26 Oct 2026 | Viewed by 155 | Submission Open

Keywords: implant biomechanics; prosthetic component design; digital implant impression techniques; peri-implant tissue health and disease management; long-term clinical outcomes and future trends in implant dentistry

(This special issue belongs to the Section Dentistry and Oral Health)

Physiotherapy and Neurorehabilitation: Emerging Trends and Therapies

edited by

Irimia Mollinedo-Cardalda

and Esther Monge Pereira

submission deadline 27 Oct 2026 | Viewed by 215 | Submission Open

Keywords: neurorehabilitation; physiotherapy; neuroplasticity; motor imagery; stroke; motor learning; pediatric neurology; telerehabilitation; virtual reality; rehabilitation technologies

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Displaying special issue 101-150 on page 3 of 8.

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