Special Issues

Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pharmacological Modulation of NRF2 submission deadline 31 May 2026 | 1 articles | Viewed by 660 | Submission Open
Keywords: NRF2; redox pharmacology; cancer; inflammatory diseases; neurodegenerative diseases; cardiovascular diseases
(This special issue belongs to the Section Pharmacology)
Decision-Making in Gastrointestinal Oncological Surgery: Balancing Techniques, Patient Factors and Global Health Needs
edited by
submission deadline 31 May 2026 | Viewed by 198 | Submission Open
Keywords: surgical oncology; upper gastrointestinal cancers; colorectal surgery; hepatobiliary and pancreatic surgery
(This special issue belongs to the Section Surgery)
New Advances in Inflammatory Bowel Disease and Diarrheal Disorders
edited by Ion Rogoveanu and
submission deadline 31 May 2026 | Viewed by 161 | Submission Open
Keywords: ulcerative colitis; Crohn’ s disease; Clostridium difficile; celiac disease; cytomegalovirus colitis; Yersinia colitis; intestinal tuberculosis; villous atrophy
(This special issue belongs to the Section Gastroenterology & Hepatology)
GLP-1 and GIP Receptor Agonists, Cardiometabolic Disease, Oxidative Stress and Dementia: Novel Insights and Challenges
edited by
submission deadline 31 May 2026 | Viewed by 148 | Submission Open
Keywords: glucagon-like peptide-1; glucose-dependent insulinotropic polypeptide; cardiometabolic disease; diabetes; hypertension; stroke; metabolic dysfunction-associated steatotic liver disease; oxidative stress; dementia
Emerging Trends in the Neurosurgical Management of Neuroendocrine Tumors
edited by Karol Wiśniewski and
submission deadline 31 May 2026 | Viewed by 113 | Submission Open
Keywords: neuroendocrine tumors; central nervous system; skull base surgery; pituitary neuroendocrine tumors (PitNETs); paraganglioma; brain metastases; endoscopic endonasal approach; microsurgery; peptide receptor radionuclide therapy (PRRT); immunohistochemistry; multidisciplinary management; stereotactic radiosurgery
(This special issue belongs to the Section Neurology)
Endometriosis: Surgical, Medical, and Multidisciplinary Challenges
edited by , Ilaria Cuccu and Fabio Barra
submission deadline 31 May 2026 | Viewed by 109 | Submission Open
Keywords: endometriosis; pelvic pain; infertility; minimally invasive surgery; medical therapy; diagnosis; multidisciplinary care
(This special issue belongs to the Section Surgery)
Current Concepts in Orthognathic and Cleft Surgery
edited by Matija Mamic
submission deadline 31 May 2026 | Viewed by 100 | Submission Open
Keywords: orthognathic surgery; cleft surgery; facial deformities; jaw surgery; orthofacial surgery; facial asymmetry; dentoskeletal deformities; orthodontic preparation; new technologies
(This special issue belongs to the Section Surgery)
Clinical Research in Minimally Invasive Cardiac Surgery
edited by , and Marcello Bergonzini
submission deadline 31 May 2026 | Viewed by 54 | Submission Open
Keywords: minimally; invasive; aortic valve; mitral valve; tricuspid valve; CABG; replacement; plastic; periferic cannulation; cardio-pulmonary by-pass; robotic
(This special issue belongs to the Section Cardiology)
Advances in Multiple Sclerosis: From Pathogenesis to Therapeutics submission deadline 1 Jun 2026 | Viewed by 91 | Submission Open
Keywords: multiple sclerosis; biomarkers; imaging; McDonald 2024 criteria; disease-modifying therapies; smoldering disease; progression independent of relapse activity; remyelination; microglia; clinical research
(This special issue belongs to the Section Neurology)
Insights and Advances in Cancer Biomarkers
edited by
submission deadline 5 Jun 2026 | 8 articles | Viewed by 14589 | Submission Open
Keywords: liquid biopsies; cancer biomarkers; cellular immunotherapy; single-cell sequencing; immune biomarkers; epigenetic markers; microbiome and metabolomics; proteomics; multiomics; machine learning; generative AI
(This special issue belongs to the Section Oncology)
Physiotherapy in Patients with Musculoskeletal Disorders submission deadline 5 Jun 2026 | Viewed by 242 | Submission Open
Keywords: physiotherapy; musculoskeletal disorders; diagnostic; treatment; prevention; multidisciplinary approach; physical therapy modalities
(This special issue belongs to the Section Orthopedics)
Modern Diagnostics and Therapy for Vitreoretinal Diseases submission deadline 10 Jun 2026 | 3 articles | Viewed by 3953 | Submission Open
Keywords: retinal pharmacotherapy; artificial intelligence; image recognition; optical coherence tomography; remote retinal monitoring; exudative retinal disease; geographic atrophy
(This special issue belongs to the Section Ophthalmology)
Updates in Physical Treatment of Musculoskeletal Disorders
edited by and Patricia Martinez-Merinero
submission deadline 10 Jun 2026 | Viewed by 117 | Submission Open
Keywords: musculoskeletal assessment; therapeutic exercise; manual therapy; invasive procedures; virtual reality; digital health applications; patient education; multidisciplinary pain treatment
(This special issue belongs to the Section Sports Medicine and Sports Traumatology)
Clinical Research in Orthopaedics and Trauma Surgery
edited by Nikolai Ramadanov and
submission deadline 15 Jun 2026 | 10 articles | Viewed by 17003 | Submission Open
Keywords: orthopaedics; trauma; arthroscopy; arthroplasty; artificial intelligence; fracture; osteoarthritis; hip; knee
(This special issue belongs to the Section Orthopedics)
Sports Injuries: Prevention, Treatment and Rehabilitation submission deadline 15 Jun 2026 | 7 articles | Viewed by 12831 | Submission Open
Keywords: exercise; return to sport; rehabilitation; sports therapy; muscle; tendon; joint; surgery; MRI
(This special issue belongs to the Section Orthopedics)
Emerging Trends in Infectious Disease Prevention and Control submission deadline 15 Jun 2026 | 4 articles | Viewed by 3589 | Submission Open
Keywords: antimicrobial resistance; antimicrobial stewardship; novel identification; molecular diagnosis; vaccines; artificial intelligence; epidemiology; healthcare policies; alternative therapy
(This special issue belongs to the Section Infectious Disease)
Emerging Therapies for Gastric Cancer submission deadline 15 Jun 2026 | 1 articles | Viewed by 1952 | Submission Open
Keywords: gastric cancer; oncology; therapies; individualized therapy; immunotherapy
(This special issue belongs to the Section Gastroenterology & Hepatology)
Advances in Knee Surgery: From Diagnosis to Recovery
edited by and In Jun Koh
submission deadline 15 Jun 2026 | 1 articles | Viewed by 649 | Submission Open
Keywords: knee surgery; arthroplasty; osteotomy; cartilage regeneration; meniscus repair; ligament reconstruction; artificial intelligence; robotics
(This special issue belongs to the Section Orthopedics)
Advances in Cancer Therapy from Fundamental Research to Clinical Practice—Multidisciplinary Treatment of Cancer (Therapies and Their Toxicity)
edited by and Nicolae Crisan
submission deadline 15 Jun 2026 | Viewed by 290 | Submission Open
Keywords: cancer; systemic therapy; surgery; molecular; research
(This special issue belongs to the Section Oncology)
Advances in Reconstructive and Plastic Surgery
edited by Tien-Hsiang Wang, Wen‐Kuan Chiu and
submission deadline 15 Jun 2026 | Viewed by 181 | Submission Open
Keywords: reconstructive surgery; plastic surgery; microsurgery; tissue engineering; regenerative medicine; wound healing; flap surgery; 3D surgical planning; limb salvage; craniofacial reconstruction; breast reconstruction; surgical innovation
(This special issue belongs to the Section Surgery)
Aortic Stenosis: Pathophysiological Mechanism, Multimodality Imaging, and Contemporary Treatment
edited by Elio Haroun and
submission deadline 15 Jun 2026 | Viewed by 151 | Submission Open
Keywords: aortic stenosis; pathophysiology; multimodality imaging; echocardiography; cardiac computed tomography (CT); cardiac magnetic resonance (CMR); transcatheter aortic valve replacement (TAVR); surgical aortic valve replacement (SAVR); risk stratification; prognosis
(This special issue belongs to the Section Cardiology)
Artificial Intelligence in Urology: A New Era of Precision and Innovation
edited by Campetella Marco and
submission deadline 15 Jun 2026 | Viewed by 140 | Submission Open
Keywords: artificial intelligence; robotic surgery; diagnosis; bladder cancer; kidney cancer; prostate cancer
(This special issue belongs to the Section Urology & Nephrology)
Parkinson’s Disease: Advances in Pathological Insights and Therapeutic Innovations
edited by Sevasti Bostantjopoulou and Ioannis Dagklis
submission deadline 15 Jun 2026 | Viewed by 115 | Submission Open
Keywords: Parkinson’ s disease; pathophysiology; disease-modifying therapies; alpha-synuclein; genetics; agents targeting GBA1 and LRRK2 activity; GLP1 agonists; microbiota; biomarkers; environmental factors and lifestyle
(This special issue belongs to the Section Neurology)
New Advances in Oral Care submission deadline 15 Jun 2026 | Viewed by 107 | Submission Open
Keywords: oral health; oral diseases; preventive dentistry; periodontal health; orofacial pain
(This special issue belongs to the Section Dentistry and Oral Health)
Recent Advances in Cervical and Vulvar Cancer
edited by Silviu Cristian Voinea and
submission deadline 19 Jun 2026 | Viewed by 574 | Submission Open
Keywords: gynaeco-oncology; women’ s health; surgery; radiotherapy; chemotherapy; lymphadenectomy; sentinel lymph node; radical hysterectomy; vulvectomy; brachytherapy
(This special issue belongs to the Section Obstetrics and Gynecology)
Cutting-Edge Research into Cancer Radiotherapy
edited by Geert O.R.J. Janssens and
submission deadline 19 Jun 2026 | Viewed by 368 | Submission Open
Keywords: FLASH radiotherapy; image-guided radiotherapy; proton therapy; real-time imaging; tumor tracking; AI linear accelerators
(This special issue belongs to the Section Oncology)
ACL: From Injury to Return to Sport
edited by
submission deadline 19 Jun 2026 | Viewed by 194 | Submission Open
Keywords: ACL; rehabilitation; neuromuscular training; return to sport; surgical techniques
(This special issue belongs to the Section Sports Medicine and Sports Traumatology)
Updates on Prevention of Acute Heart Failure
edited by
submission deadline 20 Jun 2026 | 3 articles | Viewed by 7324 | Submission Open
Keywords: acute heart failure; treatment of acute heart failure; management of acute heart failure; prevention of acute heart failure; chronic decompensated heart failure
(This special issue belongs to the Section Cardiology)
Development and Application of Digestive Endoscopy
edited by , Sara Nikolic and
submission deadline 20 Jun 2026 | 1 articles | Viewed by 1637 | Submission Open
Keywords: endoscopy; endoscopic ultrasound; interventional endoscopy; robotic endoscopy; gastroenterology; advanced imaging
(This special issue belongs to the Section Gastroenterology & Hepatology)
The Burden of COVID-19 Pandemic on Mental Health, 2nd Edition submission deadline 20 Jun 2026 | 1 articles | Viewed by 1043 | Submission Open
Keywords: COVID-19 pandemic; mental health; therapy; psychological stress; psychiatric disorders
(This special issue belongs to the Section Epidemiology & Public Health)
Artificial Intelligence in Medicine: Shaping the Future of Healthcare submission deadline 20 Jun 2026 | Viewed by 206 | Submission Open
Keywords: artificial intelligence; machine learning; diagnostic imaging; clinical decision support systems; precision medicine
New Advance in Primary and Secondary Immunodeficiencies
edited by Gary Ira Kleiner and Melissa Gans
submission deadline 22 Jun 2026 | Viewed by 143 | Submission Open
Keywords: inborn errors of immunity; immunogenetics; primary immunodeficiency; secondary immunodeficiency; immunomodulators; stem cell transplant; gene therapy
(This special issue belongs to the Section Hematology and Immunology)
Prosthodontics and Restorative Dentistry: New Insights and Future Directions
edited by Edoardo Mancuso and
submission deadline 22 Jun 2026 | Viewed by 63 | Submission Open
Keywords: prosthodontics; restorative dentistry; digital dentistry; CAD/CAM and 3D Printing; adhesive dentistry; esthetics and function; personalized dentistry
(This special issue belongs to the Section Dentistry and Oral Health)
Sports Cardiology: From Athletes to Advanced Technologies for Cardiovascular Prevention and Exercise Prescription submission deadline 25 Jun 2026 | Viewed by 144 | Submission Open
Keywords: sports cardiology; athlete’ s heart; sudden cardiac death prevention; exercise prescription; cardiovascular screening; wearable devices; artificial intelligence (AI); cardiac imaging (echocardiography; CMR); risk stratification; return to play protocols
(This special issue belongs to the Section Cardiology)
Liver Surgery: Current Treatment and Future Options
edited by
submission deadline 25 Jun 2026 | Viewed by 86 | Submission Open
Keywords: liver surgery; hepatic resection; liver transplantation; hepatocellular carcinoma; liver cirrhosis; liver failure; liver metastasis; cholangiocarcinoma
(This special issue belongs to the Section Gastroenterology & Hepatology)
Pulmonary Fibrosis: Current Understanding and Future Directions
edited by Satoshi Okamori and
submission deadline 28 Jun 2026 | 1 articles | Viewed by 1677 | Submission Open
Keywords: pulmonary fibrosis; interstitial lung disease (ILD); idiopathic pulmonary fibrosis (IPF); hypersensitivity pneumonitis; bronchoscopy; cryobiopsy; fibrotic lung disease; acute exacerbations; pleuroparenchymal fibroelastosis; rehabilitation; nutrition
(This special issue belongs to the Section Pulmonology)
New Insights into Gynecological Disease
edited by and Valentina Billone
submission deadline 30 Jun 2026 | 5 articles | Viewed by 12719 | Submission Open
Keywords: gynecological disease; endometriosis; gynecological cancer; nutraceutical supplementation; infertility; minimally invasive surgery; fertility preservation; psychological implications in gynecological malignancies; ethical and medico-legal implications; PCOS
(This special issue belongs to the Section Obstetrics and Gynecology)
Techniques, Risks and Recovery of Hip Surgery
edited by , and Enrique Guerado
submission deadline 30 Jun 2026 | 5 articles | Viewed by 4599 | Submission Open
Keywords: hip surgery; hip fracture; hip arthroplasty; hip arthroscopy  
(This special issue belongs to the Section Orthopedics)
Updates on the Changing Landscape of Immunotherapy and Targeted Therapy in Cancer submission deadline 30 Jun 2026 | 4 articles | Viewed by 3291 | Submission Open
Keywords: cancer immunotherapy; cancer targeted therapy; immune checkpoint targeted therapy; cell therapy in cancer; signal transduction inhibitors; small molecules of cancer drugs; tumor microenvironment; efficacy biomarkers for cancer therapy; mechanisms of resistance
(This special issue belongs to the Section Oncology)
Multiple Sclerosis and Related Disorders: Theory, Methods and Applications
edited by Maura Pugliatti and
submission deadline 30 Jun 2026 | 3 articles | Viewed by 2603 | Submission Open
Keywords: multiple sclerosis; biomarkers; neurodegeneration; neuroimaging; disease-modifying treatments; artificial intelligence; telemedicine; digital therapeutics; personalized medicine
(This special issue belongs to the Section Neurology)
New Research on Endodontic Therapy submission deadline 30 Jun 2026 | 1 articles | Viewed by 2562 | Submission Open
Keywords: endodontics; root canal therapy; root anatomy; pulp therapy; endodontic microsurgery; education; rotary endodontics
(This special issue belongs to the Section Dentistry and Oral Health)
Ventricular Arrhythmias: Current Advances and Future Perspectives
edited by Zefferino Palamà, and Antonio Gianluca Robles
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1172 | Submission Open
Keywords: sudden death; cardiomyopathies; catheter ablation; cardiac mapping; cardiac imaging
(This special issue belongs to the Section Cardiology)
Artificial Intelligence: A Possible 'Game Changer' in the Fight Against Cancer
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 909 | Submission Open
Keywords: artificial intelligence; cancer biology; drug discovery and repurposing; diagnosis and detection; treatment optimization; clinical practice and patient support
(This special issue belongs to the Section Oncology)
Recent Advances in Digestive Endoscopy submission deadline 30 Jun 2026 | 1 articles | Viewed by 767 | Submission Open
Keywords: digestive endoscopy; cholangiopancreatography; advanced endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatology)
Medical Imaging in the Detection of Urological Malignancies submission deadline 30 Jun 2026 | 1 articles | Viewed by 262 | Submission Open
Keywords: urological malignancies; MRI; radiomics; artificial intelligence; abdominal imaging; pelvic imaging
(This special issue belongs to the Section Urology & Nephrology)
Peripheral Artery Disease in Thromboinflammation Era: Pathophysiological, Clinical and Therapeutic Implications submission deadline 30 Jun 2026 | Viewed by 230 | Submission Open
Keywords: thromboinflammation; peripheral artery disease; atherosclerosis; acute limb ischemia
(This special issue belongs to the Section Cardiology)
Osteoporosis: Advances in Diagnosis, Risk Assessment, Surgical Treatment, and Regenerative Therapies
edited by Yusuke Oshita and Takayuki Imura
submission deadline 30 Jun 2026 | Viewed by 146 | Submission Open
Keywords: osteoporosis; fragility fracture; bone mineral density (BMD)
(This special issue belongs to the Section Orthopedics)
Motion Preservation in Spine Surgery: Joint-Sparing Strategies for Balancing Stability and Mobility
edited by Antonio Bocchetti, Raffaele de Falco and Ciro Mastantuoni
submission deadline 30 Jun 2026 | Viewed by 104 | Submission Open
Keywords: spine surgery; motion preservation; cervical disc arthroplasty; lumbar disc replacement; dynamic stabilization; hybrid constructs; minimally invasive spine surgery; adjacent segment disease
(This special issue belongs to the Section Neurology)
Recent Advances in Erectile Dysfunction
edited by Andrea Cocci and Mikolaj Frankiewicz
submission deadline 30 Jun 2026 | Viewed by 93 | Submission Open
Keywords: erectile dysfunction; male sexual health; penile prosthesis; prosthetic surgery; regenerative medicine; shockwave therapy; platelet-rich plasma; stem cell therapy; phosphodiesterase type-5 inhibitors; cardiovascular risk
(This special issue belongs to the Section Urology & Nephrology)
Cardiopulmonary Resuscitation: Current Advances and Best Practices
edited by Tiziana Bove and Francesco Meroi
submission deadline 30 Jun 2026 | Viewed by 92 | Submission Open
Keywords: resuscitation; emergency; intensive care medicine; CPR; ECLS; prognosis
(This special issue belongs to the Section Intensive Care/ Anesthesiology)
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