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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Tissue-Guided Repair

edited by

Tiberiu Paul Neagu

and

Ileana Peride

submission deadline 31 Dec 2025 | Viewed by 57 | Submission Open

Keywords: tissue injury; tissue repair; chronic wound; wound healing; wound dressing; skin homeostasis; wound microenvironment; wound contraction; scar; skin substitutes; guided regeneration

(This special issue belongs to the Section Dermatology)

Updates on Caries Management in the Primary and Permanent Dentition: 2nd Edition

edited by

Julian Schmoeckel

submission deadline 31 Dec 2025 | Viewed by 55 | Submission Open

Keywords: dental caries; treatment; caries management; children; adults; prevention; minimal-invasive

(This special issue belongs to the Section Dentistry and Oral Health)

Aortic Valve Replacement Innovations and Outcomes

edited by Basel Ramlawi and

Massimo Baudo

submission deadline 31 Dec 2025 | Viewed by 51 | Submission Open

Keywords: aortic valve replacement; cardiac surgery; minimally invasive; transcatheter; innovation; clinical outcomes; aortic stenosis; aortic regurgitation; technology

(This special issue belongs to the Section Cardiology)

Advances in GLP-1 Agonists and Liver Disease

edited by

Emidio Scarpellini

submission deadline 31 Dec 2025 | Viewed by 33 | Submission Open

Keywords: GLP-1 agonist; liver disease; liver steatosis; obesity; liver fibrosis

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advancements in Dental Medicine, Oral Anesthesiology and Surgery

edited by Cosmin Sinescu,

Ciprian Roi

and

Mircea Riviș

submission deadline 10 Jan 2026 | 7 articles | Viewed by 6967 | Submission Open

Keywords: oral surgery; oral anesthesiology; implantology and guided surgery; oral tissue regeneration; periodontal disease; dental materials; oral medical devices; oral diseases

(This special issue belongs to the Section Dentistry and Oral Health)

Advances in Diagnosis and Therapies of Ocular Diseases

edited by

Ana Maria Dascalu

submission deadline 10 Jan 2026 | 2 articles | Viewed by 2535 | Submission Open

Keywords: early biomarkers; retinal and optic nerve imaging; ocular surgery; glaucoma drainage devices; neuroprotection; refraction errors; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Diabetes, Hypertension, and Cardiovascular Diseases: New Insights, Risk Factors, and Drug Therapies

edited by

Christina Chrysohoou

Panagiotis Theofilis

and

Emmanouil Mantzouranis

submission deadline 10 Jan 2026 | Viewed by 176 | Submission Open

Keywords: diabetes; hypertension; cardiovascular disease; cardiovascular risk factors; novel drug therapies; novel therapies; coronary artery disease; heart failure; precision medicine; artificial intelligence

(This special issue belongs to the Section Cardiology)

New Insights into Hypertension and the Cardiovascular System: 2nd Edition

edited by

Gwo-Ping Jong

submission deadline 15 Jan 2026 | Viewed by 72 | Submission Open

Keywords: hypertension; risk factors; oxidative stress; chronic inflammation; cardiovascular diseases

(This special issue belongs to the Section Cardiology)

Nutritional Management of Adults with Obesity

edited by

Alessandro Laviano

and

Salvatore Vaccaro

submission deadline 20 Jan 2026 | Viewed by 462 | Submission Open

Keywords: obesity; metabolic phenotype of obesity; nutritional management; nutritional intervention; nutritional educational program; precision nutrition; food compounds; dietary patterns; medical nutrition therapy (MNT); lifestyle intervention; physical activity program; traditional and innovative diets; therapeutic innovations

(This special issue belongs to the Section Endocrinology)

Craniomaxillofacial Surgery 4.0: Personalized Digital Planning, Augmented Reality, Point-of-Care Manufacturing and Molecular Data Integration

edited by

Maria J. Troulis

and

Manuel Tousidonis

submission deadline 20 Jan 2026 | Viewed by 62 | Submission Open

Keywords: craniomaxillofacial surgery; 3D printing; point-of-care manufacturing; microsurgery; reconstructive surgery; head and neck oncolog; rare jaw tumors; CCOC; minimally invasive surgery; tissue engineering; personalized digital planning; augmented reality; molecular data integration

(This special issue belongs to the Section Dentistry and Oral Health)

Recent Advances in Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia

edited by

Apostolos Apostolidis

and Efstathios Papaefstathiou

submission deadline 20 Jan 2026 | Viewed by 42 | Submission Open

Keywords: LUTS; BPH; minimally invasive treatment; digital health tools; biomarkers; microbiome

(This special issue belongs to the Section Urology & Nephrology)

Minimally Invasive Procedures in Cardiac Care

edited by

Antonello D’Andrea

Vincenzo Russo

and

Alfredo Mauriello

submission deadline 24 Jan 2026 | 2 articles | Viewed by 2459 | Submission Open

Keywords: minimally invasive cardiac care; valve surgery; coronary artery bypass grafting; heart failure management; surgical techniques; implantable cardioverter defibrillator; pacemaker; stellate ganglion blockage; aortic valve; mitral valve; hybrid approaches

(This special issue belongs to the Section Cardiology)

Recent Advances and Future Challenges in Orthopaedic Trauma Surgery

edited by Zinon Kokkalis and

Dimitrios Ntourantonis

submission deadline 25 Jan 2026 | Viewed by 87 | Submission Open

Keywords: orthopaedic trauma; fracture fixation; polytrauma; non-union; geriatric fractures; implant design; surgical innovation; perioperative care; postoperative rehabilitation

(This special issue belongs to the Section Orthopedics)

Advancements and Outcomes in Transcatheter Aortic Valve Implantation (TAVI)

edited by Dimitrios Iliopoulos and

Nikolaos Schizas

submission deadline 25 Jan 2026 | Viewed by 45 | Submission Open

Keywords: TAVI; transcatheter aortic valve implantation; TAVR; aortic valve replacement; aortic valve stenosis

(This special issue belongs to the Section Cardiology)

Exercise Rehabilitation Strategies for Long-Term Conditions in the Post-Pandemic Era

edited by

David Varillas-Delgado

and Sofía Laguarta-Val

submission deadline 26 Jan 2026 | Viewed by 31 | Submission Open

Keywords: therapeutic exercise; long covid; post-COVID syndrome; sports medicine; rehabilitation medicine; physiotherapy

(This special issue belongs to the Section Epidemiology & Public Health)

Minimally Invasive Strategies and New Techniques in Cardiovascular Surgery

edited by

Alexander Weymann

, Horatiu Suciu and

Marius Mihai Harpa

submission deadline 30 Jan 2026 | Viewed by 141 | Submission Open

Keywords: minimally invasive; endoscopic surgery; mitral repair; mini-thoracotomy; hybrid approach; percutaneous therapy

(This special issue belongs to the Section Cardiology)

The Association Between Cardiovascular Disease and Lung Cancer

edited by

Francesk Mulita

and

Vasileios Leivaditis

submission deadline 30 Jan 2026 | Viewed by 41 | Submission Open

Keywords: cardiovascular disease; lung cancer; incidence; mortality; survival; radiotherapy; chemotherapy

(This special issue belongs to the Section Cardiology)

Medicine and Dentistry: New Methods and Clinical Approaches—2nd Edition

edited by

Stefano Rizza

and Rocco Franco

submission deadline 31 Jan 2026 | 11 articles | Viewed by 20029 | Submission Open

Keywords: oral health; new materials; medical approach; periodontal disease; bruxism; oral surgery

(This special issue belongs to the Section Dentistry and Oral Health)

Current and Future Trends in Dentistry and Oral Health

edited by

Eva Klarić

Bruno Špiljak

and

Luka Šimunović

submission deadline 31 Jan 2026 | 4 articles | Viewed by 4030 | Submission Open

Keywords: digital dentistry; artificial intelligence in dentistry; biomaterials; orthodontics; endodontics; periodontics; oral– systemic health; dental public health; esthetic dentistry; implantology

(This special issue belongs to the Section Dentistry and Oral Health)

Clinical Recent Research in Rehabilitation and Preventive Medicine

edited by Mihai Berteanu,

Marius Nicolae Popescu

and

Mădălina-Gabriela Iliescu

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3213 | Submission Open

Keywords: physical medicine; rehabilitation; injury prevention; wearable sensor devices (WSDs); biomechanics; regenerative medicine; musculoskeletal ultrasound (MSKUS); AI in medicine; telehealth; motion analysis

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Novel Innovations in Diabetes Mellitus Prevention, Screening and Management

edited by

Anca Pantea Stoian

Teodor Salmen

and

Mihaela Adela Iancu

submission deadline 31 Jan 2026 | 3 articles | Viewed by 2462 | Submission Open

Keywords: diabetes mellitus; prevention; screening; complications; cardiovascular disease; neuropathy; retinopathy; nephropathy

(This special issue belongs to the Section Endocrinology)

Anterior Cruciate Ligament (ACL) Injury

edited by

Riccardo D'Ambrosi

and Alessandro Carrozzo

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2334 | Submission Open

Keywords: anterior cruciate ligament; anterolateral ligament; arthroscopy; knee; sports medicine

(This special issue belongs to the Section Orthopedics)

Advances in Gynecological Cancer Research: Emerging Technologies and Future Therapeutic Strategies

edited by Jae-Yun Song and

Seongmin Kim

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1737 | Submission Open

Keywords: gynecological cancer; innovative surgical techniques; genomic profiling; personalized medicine; artificial intelligence (AI) in oncology; machine learning in diagnosis; cancer research technologies; future therapeutic strategies

(This special issue belongs to the Section Obstetrics and Gynecology)

Cardiovascular Disease: From Clinical Diagnosis to Management and Treatment

edited by Florin Mitu,

Maria-Magdalena Leon

and

Alexandra Maștaleru

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1419 | Submission Open

Keywords: cardiovascular disease; cardiac rehabilitation; secondary prevention; innovative treatment; risk stratification

(This special issue belongs to the Section Cardiology)

Recent Advances in Anesthesiology and Pain Medicine

edited by Adam Rudnik and

Izabela Duda

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1242 | Submission Open

Keywords: anesthetic procedures; perioperative monitoring; airway management; pain management; standards of anesthesia; perioperative care

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Clinical Advances in Cardiopulmonary Bypass Surgery: Innovations and Impacts on Patient Outcomes

edited by

Irina-Iuliana Costache

Ștefania-Teodora Duca

and Lucian Stoica

submission deadline 31 Jan 2026 | Viewed by 494 | Submission Open

Keywords: cardiac surgery; cardiopulmonary bypass; patient outcome; surgical techniques; extracorporeal circulation; postoperative care; perfusion strategies

(This special issue belongs to the Section Cardiology)

Clinical Treatment of Neuroendocrine Neoplasm

edited by Michele Klain and

Leandra Piscopo

submission deadline 31 Jan 2026 | Viewed by 221 | Submission Open

Keywords: neuroendocrine neoplasms; neuroendocrine cell system; gastro-entero-pancreatic NENs; immunohistochemical analysis; Ki-67 index; mitotic count; somatostatin analogue therapy; antiproliferative effect; positron emission tomography/computed tomography (PET/CT); peptide receptor radionuclide therapy (PRRT)

(This special issue belongs to the Section Oncology)

Coronary CT Angiography in Coronary Artery Disease: Challenges and Future Opportunities

edited by

Nikolaos Ktenopoulos

and Andreas Synetos

submission deadline 31 Jan 2026 | Viewed by 100 | Submission Open

Keywords: coronary CT angiography; coronary artery disease; cardiac imaging; non-invasive imaging; INOCA/ANOCA

(This special issue belongs to the Section Cardiology)

Diagnosis and Management of Upper Tract Urothelial Carcinomas

edited by

Yao-Chou Tsai

and

Shu-Yu Wu

submission deadline 31 Jan 2026 | Viewed by 84 | Submission Open

Keywords: upper urinary tract urothelial carcinoma (UTUC); nephroureterectomy; urinary tract biomarkers; chemotherapy; endoscopic management; molecular profiling; surgical treatment; target therapy

(This special issue belongs to the Section Urology & Nephrology)

Research Progress in Oral and Periodontal Surgery

edited by

Pradeep Koppolu

submission deadline 31 Jan 2026 | Viewed by 83 | Submission Open

Keywords: implants; biomarkers; mucogingival procedures; regeneration; lasers

(This special issue belongs to the Section Dentistry and Oral Health)

The Laparoscopy in Abdominal Surgery

edited by

Dan Tudor Eniu

and

Bogdan Stancu

submission deadline 31 Jan 2026 | Viewed by 77 | Submission Open

Keywords: abdominal hernia; laparoscopy; robotics; mesh; colorectal cancer; acute cholecystitis; appendicitis; gynecological surgery

(This special issue belongs to the Section Surgery)

Lung Injury and Acute Respiratory Distress Syndrome: New Insights into Mechanisms and Emerging Therapies

edited by

Denise Battaglini

and

Raffaele Merola

submission deadline 31 Jan 2026 | Viewed by 74 | Submission Open

Keywords: acute respiratory distress syndrome; lung injury; mechanical power; mechanical ventilation; transpulmonary pressure; ventilator-induced lung injury

(This special issue belongs to the Section Pulmonology)

Advances in Gastrointestinal Surgeries

edited by Matei Bratu, Bogdan Diaconescu and Florin Iordache

submission deadline 31 Jan 2026 | Viewed by 67 | Submission Open

Keywords: minimal invasive surgery; oncologic surgery; endoscopic surgery; rare cases

(This special issue belongs to the Section Surgery)

Clinical Ophthalmology: Current Status and Future Challenges

edited by

Theodora Papamitsou

, Athanasios Karamitsos and

Sofia Karachrysafi

submission deadline 31 Jan 2026 | Viewed by 67 | Submission Open

Keywords: clinical ophthalmology; ophthalmic pharmacology; biomarkers in eye diseases; ocular diagnostics; AI in ophthalmology; minimally invasive eye surgery; retinal diseases; gene therapy in ophthalmology; surgical innovations in ophthalmology; regenerative medicine for eye diseases

(This special issue belongs to the Section Ophthalmology)

Cutaneous Lymphoma: From Pathogenesis to Therapy

edited by Alina Jankowska-Konsur and

Magdalena Łyko

submission deadline 31 Jan 2026 | Viewed by 55 | Submission Open

Keywords: cutaneous lymphoma; mycosis fungoides; CTCL; CBCL; Sezary’ s syndrome; pathogenesis; therapy

Advances in Trauma Resuscitation with Focus on Musculoskeletal Injuries

edited by Kuang-Ting Yeh

submission deadline 31 Jan 2026 | Viewed by 40 | Submission Open

Keywords: damage control orthopedics; trauma-induced coagulopathy; timing of fracture fixation; hemostatic resuscitation; pelvic trauma management; extremity vascular injuries; compartment syndrome; polytrauma resuscitation; orthopedic damage control; early total care vs. damage control

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Multiple Sclerosis: Recent Advances in Clinical Diagnosis and Treatment

edited by

Vasileios Giannopapas

, John Tzartos and Sotirios Giannopoulos

submission deadline 31 Jan 2026 | Viewed by 37 | Submission Open

Keywords: multiple sclerosis; demyelination; diagnostic criteria; treatment; disease-modifying therapies; comorbidities; rehabilitation; management

Atrial Fibrillation: Clinical Complications and Treatment

edited by

Oskars Kalejs

submission deadline 31 Jan 2026 | Viewed by 37 | Submission Open

Keywords: atrial fibrillation [AFib]; rhythm control; rate control; triggers of AFib; antiarrhythmic pharmacy; upstream therapy; non-direct antiarrhythmic pharmacy; catheter ablation; prevention of stroke and systemic embolism; anticoagulants; AF-CARE concept

(This special issue belongs to the Section Cardiology)

Emerging Trends in Head and Neck Surgery

edited by Filippo Carta, Roberto Puxeddu and

Cinzia Mariani

submission deadline 31 Jan 2026 | Viewed by 32 | Submission Open

Keywords: head and neck surgery; minimally invasive surgical approaches; new technologies; personalized medicine; artificial intelligence

(This special issue belongs to the Section Surgery)

Update on Surgical Treatment for Ovarian Cancer

edited by

Christos R. Iavazzo

and Victoria Psomiadou

submission deadline 31 Jan 2026 | Viewed by 20 | Submission Open

Keywords: ovarian cancer; surgical resection; ovariotomy; HIPEC (hyperthermic intraperitoneal chemotherapy); minimally invasive surgery (MIS); neoadjuvant chemotherapy (NACT); fertility-preserving procedures; AI-assisted technologies

(This special issue belongs to the Section Obstetrics and Gynecology)

Current Trends and Challenges in the Diagnosis and Management of Pediatric Knee Disorders

edited by Marcin K. Krzysztof Waśko

submission deadline 31 Jan 2026 | Viewed by 13 | Submission Open

Keywords: patellar instability in children; osteochondritis dissecans; discoid meniscus; pediatric ACL tears; meniscal injuries in children; tibial spine avulsion fracture; physeal injuries of the knee; genu valgum/genu varum; Blount’ s disease; juvenile idiopathic arthritis of the knee

(This special issue belongs to the Section Orthopedics)

From Conception to Birth: Embryonic Development and Disease

edited by

Paschalis Theotokis

, Soultana Meditskou and

Maria Eleni Manthou

submission deadline 1 Feb 2026 | 4 articles | Viewed by 3434 | Submission Open

Keywords: embryology; organogenesis; cell differentiation; gametes; reproduction; sex ratio; birth defects; pathophysiology; disease

Evaluation, Management, and Outcomes in Perioperative Medicine

edited by Yale Tung-Chen and

Francisco Javier García Sánchez

submission deadline 15 Feb 2026 | Viewed by 210 | Submission Open

Keywords: perioperative medicine; surgical outcomes; prehabilitation; risk stratification; patient optimization; enhanced recovery; multimorbidity; postoperative complications; functional recovery; patient-centered care

(This special issue belongs to the Section Surgery)

Advances in Otorhinolaryngologic Diseases

edited by Karine Aubry, Mario Bilić and

Lana Kovač Bilić

submission deadline 15 Feb 2026 | Viewed by 74 | Submission Open

Keywords: cochlear implant; ear surgery; otology; laryngeal cancer; oropharyngeal cancer; nasal polyposis; rhinoplasty; endoscopic sinus surgery; robotic surgery; dysphonia

(This special issue belongs to the Section Surgery)

New Insights into Cerebrovascular Disease

edited by Carolina Peña-Martínez

submission deadline 16 Feb 2026 | Viewed by 54 | Submission Open

Keywords: cerebrovascular disease; stroke; small-vessel disease; vascular dementia; neuroinflammation

(This special issue belongs to the Section Neurology)

Advanced Ultrasound Technology and Its Application to Gynecologic Practice

edited by

Panagiotis Peitsidis

and Marco Gergolet

submission deadline 25 Feb 2026 | Viewed by 642 | Submission Open

Keywords: gynecology; ultrasound; uterus; adnexa; pelvis; diagnosis

(This special issue belongs to the Section Obstetrics and Gynecology)

Craniomaxillofacial Surgery: Latest Innovations and Challenges

edited by Marius Octavian Pricop and Serban Talpos-Niculescu

submission deadline 25 Feb 2026 | Viewed by 239 | Submission Open

Keywords: maxillofacial and oral oncology; infections; orthognatic surgery; clefts; reconstructive surgery; bone regeneration; trauma

(This special issue belongs to the Section Surgery)

Recent Advances in Coronary Heart Disease and Related Complications

edited by

Konstantinos Tsioufis

and

Panayiotis Iliakis

submission deadline 25 Feb 2026 | Viewed by 86 | Submission Open

Keywords: cardiology; hypertension; cardiovascular disease; coronary heart disease; structural heart disease; genomics; proteomics; interventional treatment; percutaneous coronary interventions; imaging; gene therapy

(This special issue belongs to the Section Cardiology)

Application of Artificial Intelligence in Disease Diagnosis and Treatment

edited by Ricardo Martinez-Murillo and

Oscar Casanova Carvajal

submission deadline 25 Feb 2026 | Viewed by 33 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; medical diagnosis; clinical decision support; predictive modelling; medical imaging; personalised medicine; healthcare AI applications; explainable AI

(This special issue belongs to the Section Epidemiology & Public Health)

Childhood and Adolescent Obesity: Risk Factors, Complications and Management

edited by Julian Hamilton-Shield and Dinesh Giri

submission deadline 25 Feb 2026 | Viewed by 29 | Submission Open

Keywords: childhood obesity; adolescent obesity; obesity risk factors; metabolic syndrome

(This special issue belongs to the Section Pediatrics)

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