Proteomic and Metabolomic Analyses of Fisheries and Aquaculture

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 2472

Special Issue Editor


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Guest Editor
Centre of Marine Sciences (CCMAR), Universidade do Algarve, Campus de Gambelas, 8005-139 Faro, Portugal
Interests: proteomics; metabolomics; fish nutrition; allergenicity; aquaculture

Special Issue Information

Dear Colleagues,

Aquaculture is an intensive and fast-growing industry that is designed to cope with a high demand for fish products. It is estimated that aquaculture can provide 62 percent of the total fish consumption by 2030. The latest guidelines for animal welfare, food safety, and the environment, besides consumer’s acceptance of farmed fish, are a challenge for the industry. Nutritional studies provide data about more sustainable ingredients in feeds, improving the production efficiency and fishes’ health/performance, which, therefore, comply with the sustainable development goals of the United Nations 2030 agenda. Furthermore, cutting-edge technologies like proteomics and metabolomics contribute to the study of fishes’ performance and welfare.

This Special Issue of Metabolites on proteomic and metabolomic analyses of fisheries and aquaculture will focus on studies of fish tissues and fluids resulting from wild fisheries and/or fish farming practices, including nutritional and welfare studies. In addition, new methods and data analysis concepts will be presented.

Dr. Denise Schrama
Guest Editor

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Keywords

  •  proteomics
  •  metabolomics
  •  aquaculture
  •  fisheries
  •  fish nutrition
  •  fish welfare
  •  fish pathology

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Published Papers (1 paper)

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Research

22 pages, 4088 KiB  
Article
Metabolomics and Multi-Omics Determination of Potential Plasma Biomarkers in PRV-1-Infected Atlantic Salmon
by Lada Ivanova, Oscar D. Rangel-Huerta, Haitham Tartor, Maria K. Dahle, Silvio Uhlig and Christiane Kruse Fæste
Metabolites 2024, 14(7), 375; https://doi.org/10.3390/metabo14070375 - 2 Jul 2024
Viewed by 1831
Abstract
Metabolomic analysis has been explored to search for disease biomarkers in humans for some time. The application to animal species, including fish, however, is still at the beginning. In the present study, we have used targeted and untargeted metabolomics to identify metabolites in [...] Read more.
Metabolomic analysis has been explored to search for disease biomarkers in humans for some time. The application to animal species, including fish, however, is still at the beginning. In the present study, we have used targeted and untargeted metabolomics to identify metabolites in the plasma of Atlantic salmon (Salmo salar) challenged with Piscine orthoreovirus (PRV-1), aiming to find metabolites associated with the progression of PRV-1 infection into heart and skeletal muscle inflammation (HSMI). The metabolomes of control and PRV-1-infected salmon were compared at three time points during disease development by employing different biostatistical approaches. Targeted metabolomics resulted in the determination of affected metabolites and metabolic pathways, revealing a substantial impact of PRV-1 infection on lipid homeostasis, especially on several (lyso)phosphatidylcholines, ceramides, and triglycerides. Untargeted metabolomics showed a clear separation of the treatment groups at later study time points, mainly due to effects on lipid metabolism pathways. In a subsequent multi-omics approach, we combined both metabolomics datasets with previously reported proteomics data generated from the same salmon plasma samples. Data processing with DIABLO software resulted in the identification of significant metabolites and proteins that were representative of the HSMI development in the salmon. Full article
(This article belongs to the Special Issue Proteomic and Metabolomic Analyses of Fisheries and Aquaculture)
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