Metabolomics in Pulmonary Diseases
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Cell Metabolism".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 4890
Special Issue Editors
Interests: metabolomics in critical care medicine; bacterial and viral diseases of the pulmonary system
Interests: sarcoidosis; nontuberculous mycobacteria; bronchial epithelial cells; ex-vivo lung model; animal model of pulmonary diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolomics, the comprehensive analysis of small molecules in biological samples, has emerged as a powerful tool in the field of pulmonary medicine such as chronic obstructive pulmonary disease (COPD), asthma, pulmonary fibrosis, Sarcoidosis, lung cancer, and viral and bacterial pneumonia. Pulmonary diseases encompass a wide range of conditions that are characterized by complex pathophysiological processes involving inflammation, oxidative stress, tissue remodeling, and metabolic dysregulation. One of the key rationales for utilizing metabolomics in pulmonary diseases is the ability to capture the dynamic metabolic changes occurring in the lungs and systemic circulation. Metabolites represent the end products of cellular metabolism and reflect the functional state of cells and tissues. By analyzing the global metabolic profile, metabolomics can provide a snapshot of the metabolite alterations associated with pulmonary diseases that can unravel dysregulated metabolic pathways in different lung conditions. This holistic approach allows for the identification of novel biomarkers for early diagnosis, disease classification, and insights into the molecular processes driving disease progression. Using metabolomics, the accurate clustering of pulmonary diseases can facilitate personalized medicine approaches that may hold great promise for improving treatment outcomes, minimizing side effects, and enhancing patient care in pulmonary disease. The scope of this Special Issue includes preclinical and clinical research in the field of metabolomics in pulmonary diseases. The Special Issue welcomes original articles, reviews, and perspectives that contribute to understanding metabolic alterations, diagnostics and prognostics biomarker discovery and stratification of diseases. We encourage submissions of papers using various metabolomics platforms including mass spectrometry, nuclear magnetic resonance and other analytical techniques on human clinical samples, animal models, and cell cultures. This Special Issue aims to provide an opportunity for researchers and experts in the field to share their new findings, methods and ideas about metabolomics and lung diseases.
Dr. Mohammad Mehdi Banoei
Dr. Mehdi Mirsaeidi
Guest Editors
Manuscript Submission Information
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Keywords
- metabolomics
- diagnostic and prognostic biomarkers
- pathogenesis
- inflammation
- progression of disease
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