Interplay between Genomic Alterations and Metabolism in Cancer
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Integrative Metabolomics".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 1945
Special Issue Editors
Interests: cancer genomics; translational cancer research
Special Issue Information
Dear Colleagues,
During the last decade, omics technologies have revolutionized our understanding of cancer biology. Genomic, epigenomic, transcriptomic, and metabolomic profiling of cancers has brought forth unprecedented advances in basic and clinical cancer research. The integration of multi-omics information, exploiting computational and algorithmic tools, takes us a step closer to understanding the physiology and behavior of cancer cells, paving the way for the identification of new biomarkers and therapeutic targets. Τhe role of cellular metabolism in cancer has been known since the 1920s, thanks to the pioneering studies of Warburg on aerobic glycolysis. Today, it is well established that metabolic reprogramming of cancer cells is regulated by both oncogenes and tumor suppressors during tumor initiation, progression, and metastasis.
This Special Issue on “Interplay between Genomic Alterations and Metabolism in Cancer” aims to attract original contributions that address key aspects of cancer biology relevant to elucidating the oncogenic mutation-driven metabolic alterations in cancer cells, profiling the cellular response upon treatment with bioactive compounds, and understanding the role of metabolic pathways in acquired resistance to anticancer agents. Literature reviews as well as innovative studies are welcomed and will be considered for publication.
Dr. Olga Papadodima
Dr. Konstantinos Voutetakis
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer metabolism
- genomics
- transcriptomics
- metabolomics
- acquired resistance
- driver mutations
- integrative analysis
- cancer biology
- biomarkers and therapeutic targets
