Integration of Proteomics and Metabolomics: A Comprehensive Approach to Omics Research
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Advances in Metabolomics".
Deadline for manuscript submissions: closed (28 February 2026) | Viewed by 2170
Special Issue Editor
Interests: metabolomics; proteomics; metabolic flux analysis; PTMs; cross-omics; data integration; systems biology; computational modelling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The regulatory interplay between metabolism, hub molecules, proteins, and protein modification is known to regulate cellular homeostasis, and alterations can lead to disease development. Cross-omics approaches combining proteomics, metabolomics, and fluxomics are powerful tools to elucidate molecular mechanisms and gain functional insights into cellular homeostasis and pathobiochemical phenotypes. However, combined proteomic and metabolomic analyses remain an analytical challenge. Ideally, metabolite and protein compositions are analyzed simultaneously and are dynamically and spatially resolved. This requires the development of strategies at the level of sample preparation, mass spectrometric acquisition, bioinformatic analysis, computational modelling, and, in particular, data integration.
This Special Issue collects papers reporting on the recent developments and applications of innovative approaches in metabolomics, proteomics, and fluxomics, including computational omics, to provide new insights into the molecular aspects of pathophysiology and biochemistry in cellular homeostasis, health, and disease.
Dr. Marcel Kwiatkowski
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolomics
- proteomics
- metabolic flux analysis
- PTMs
- cross-omics
- data integration
- systems biology
- computational modelling
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