Advances in Metabolism in Mucosal Immunity
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Advances in Metabolomics".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 7982
Special Issue Editor
Special Issue Information
Dear Colleagues,
The gastrointestinal tract is the largest immune organ in the body. It has co-evolved with commensal microbiota to protect the host from infection and maintain gut homeostasis. The intestinal microbiome is critical for proper development and function of mucosal immunity. Recent evidence suggests that this interaction is in part dependent on the metabolites produced by the bacteria. How microbiota-specific metabolites influence the function and presence of mucosal immune cells is just beginning to be elucidated.
Many questions remain in the field: Which metabolites are important? How do they regulate innate and adaptive immune cells? Are there particular ones that are associated with intestinal diseases? When do they first appear in the intestine? As such, this Special Issue of Metabolites will be focused on publishing new advances in our knowledge on functional characterization of bacterial metabolites, identification of novel bacterial metabolites involved in mucosal immune regulation and disease, and mechanisms of how metabolites regulate intestinal immunity.
Dr. Liza Konnikova
Guest Editor
Manuscript Submission Information
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Keywords
- SCFA
- bacterial byproducts
- metabolites
- intestinal mucosa
- immunity
- microbiome
- inflammation
- homeostasis
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