Metabolic Volume Measurements

Dear Colleagues,

Metabolic volume refers to the volume of a region in PET scans that has a specific clinical interest. Metabolic volume measurements have mostly been applied to oncology for the quantitative analysis of tumors, and several studies suggest that this parameter, termed metabolic tumor volume, may hold significant diagnostic and prognostic value. However, technical issues, lack of measuring standards, and incosistent results may be reasons for the reluctance to clinically adopt this metric to-date. Challenges in region segmentation or in the identification of an optimum marker, such as total lesion glycolycis or actual lesion volume size, need to be further explored in order to clearly demonstrate the clinical value of metabolic volume measurements, which seem to be of consequence, not only to oncology, but also to inflammatory conditions and neurological disorders such as depression or dementia. Therefore, we invite both technical and clinical studies covering a wide range of metabolic volume measurement methodologies and applications.  The aim is to offer a diverse, state-of-the-art perspective on the role of metabolic volume in PET studies; explore the clinical significance of this metric; and its impact in treatment planning, patient management, and the prognosis of a disease.

Dr. Maria Kallergi
Guest Editor

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