Advances in Murine Models for Metabolic Diseases: Insights into Diabetes, Obesity, and Cardiovascular Conditions
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: 1 July 2025 | Viewed by 721
Special Issue Editor
Interests: metabolic diseases; chronic degenerative diseases; endocrinology; inflammation; oxidative stress; biochemistry; molecular biology
Special Issue Information
Dear Colleagues,
Advances in murine models are crucial for understanding the complex interplay of metabolic diseases like diabetes, obesity, and cardiovascular conditions. This Special Issue of Metabolites focuses on cutting-edge research utilizing these models to dissect disease mechanisms and identify potential therapeutic targets.
Focus: This Special Issue emphasizes innovative approaches in the murine modeling of metabolic diseases. This includes genetically modified mice (e.g., knockouts, knock-ins, and transgenics), diet-induced models (e.g., high-fat diet and high-fructose diet), and combined approaches that mimic the multifaceted nature of human diseases. We also encourage submissions exploring the impact of gut microbiota, inflammation, and other contributing factors on metabolic dysfunction in these models.
Scope: This Special Issue covers a broad spectrum of research areas, including the following:
- Mechanistic studies investigating the molecular pathways involved in disease development and progression.
- Preclinical testing of novel therapeutic interventions, including pharmacological agents, dietary interventions, and gene therapies.
- Studies exploring the link between metabolic disorders and related complications, such as cardiovascular disease, neuropathy, and nephropathy.
- Development and validation of new techniques for assessing metabolic phenotypes in mice, including metabolomics, imaging, and physiological measurements.
Purpose: This Special Issue aims at providing a comprehensive overview of the current state of the art in murine models of metabolic diseases. It serves as a valuable resource for researchers in the field, facilitating the exchange of knowledge and fostering collaborations. By highlighting recent advances and identifying knowledge gaps, this Special Issue will guide future research and accelerate the development of effective strategies for preventing and treating human metabolic disorders.
Prof. Dr. Samuel Treviño
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- murine models
- metabolic diseases
- molecular mechanisms
- biochemical pathways
- pharmacological strategies
- interactome
- comorbidities
- metabolic phenotypes
- novel techniques
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