Microfluidic for High-Throughput Screening
A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "C:Chemistry".
Deadline for manuscript submissions: closed (25 February 2020) | Viewed by 25699
Special Issue Editor
Interests: microfludics; organ-on-a-chip; in vitro models; drug screening
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microfluidics and lab-on-a-chip technologies have increasingly been used in the past two decades for miniaturizing biochemical analysis and cell-based screening assays. Following the rapid development of a variety of single-phase and multi-phase microfluidic techniques, scalable and complex architectures have been proposed for both single-cell analysis and in vitro models of disease. Therefore, by combining the miniaturization benefits of microfluidics with advances in microfabrication techniques, these systems provide an excellent platform for high-throughput screening applications, offering cost-saving opportunities compared to a standard well-plate based system. Such features offer unique capabilities for screening limited samples of human tissue, ultra-low sample volumes, stem cell research, and for innovating drug discovery, all of which can impact biological investigation, clinical practice, and industrial procedures. In particular, the integration of physiologically relevant in vitro models of disease has great potential to reduce animal-based research and aid precision medicine.
Accordingly, this Special Issue seeks to showcase research papers, short communications, and review articles that focus on novel microfluidic systems and novel methodological application of microfluidic techniques for high-throughput and high content screening, high-throughput experimentation, automation, and large-scale identification/manipulation of biological tissue.
Dr. Michele Zagnoni
Guest Editor
Manuscript Submission Information
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Keywords
- Microfluidics
- High-throughput screening
- Large-scale experimentation
- High content screens
- Miniaturized drug discovery
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