Antimicrobial Resistance in Enterobacteriaceae and Enterococci

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".

Deadline for manuscript submissions: 15 September 2024 | Viewed by 596

Special Issue Editor


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Guest Editor
Tecnologico de Monterrey, School of Engineering and Sciences, Querétaro 76130, CP, Mexico
Interests: antimicrobial resistance; enterobacteriaceae

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) is a serious problem for public health worldwide, affecting communities, production systems, and the environment, having become a growing crisis that challenges the usual implementation of epidemiological control strategies. The emergence and spread of resistant strains jeopardizes the effectiveness of previously effective antibiotics, making our therapeutic arsenal increasingly less effective in fighting even the most common infections.

It is estimated that if effective control measures are not implemented, AMR may become the leading global cause of death by 2050. The continued evolution of resistant strains of Enterobacteriaceae and Enterococci has generated “Superbugs”, causing untreatable infections and increasing mortality, morbidity, and health-related costs within society. The repercussions extend beyond the clinical setting, infiltrating communities and economies, as health systems are strained by the burden of resistant infections.

This Special Issue attempts to bring together significant contributions regarding the factors that contribute to the emergence, dissemination, management, and control of AMR in these important bacterial groups. Contributions may include molecular mechanisms, clinical implications, and epidemiological dimensions of AMR.

We extend an invitation to researchers to contribute through research articles, reviews, short communications, and case reports.

Prof. Dr. Marcos De Donato
Guest Editor

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Keywords

  • molecular mechanisms of resistance
  • clinical implications
  • epidemiology
  • outbreak
  • global health One Health
  • antibiotic resistance
  • public health
  • environment

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Published Papers (1 paper)

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Research

15 pages, 1482 KiB  
Article
Microbiological Quality of Coconut Water Sold in the Grande Vitória Region, Brazil, and Phenogenotypic Antimicrobial Resistance of Associated Enterobacteria
by Valéria Modolo Peterle, Juliana Aliprandi Bittencourt Cardoso, Carolina Magri Ferraz, Delcimara Ferreira de Sousa, Natália Pereira, Alessandra Figueiredo de Castro Nassar, Vanessa Castro, Luis Antonio Mathias, Marita Vedovelli Cardozo and Gabriel Augusto Marques Rossi
Microorganisms 2024, 12(9), 1883; https://doi.org/10.3390/microorganisms12091883 (registering DOI) - 12 Sep 2024
Viewed by 357
Abstract
This study aimed to evaluate the microbiological quality of coconut water sold from street carts equipped with cooling coils or refrigerated at bakeries in the Grande Vitória Region, Brazil. Additionally, it assessed the phenotypic and genotypic antimicrobial resistance profiles of isolated enterobacteria. The [...] Read more.
This study aimed to evaluate the microbiological quality of coconut water sold from street carts equipped with cooling coils or refrigerated at bakeries in the Grande Vitória Region, Brazil. Additionally, it assessed the phenotypic and genotypic antimicrobial resistance profiles of isolated enterobacteria. The results indicated that coconut water sold at street carts had lower microbiological quality compared to refrigerated samples, as evidenced by significantly higher counts of mesophilic microorganisms. Using MALDI-TOF, the following opportunistic pathogens were identified: Citrobacter freundii, Enterobacter bugandensis, E. kobei, E. roggenkampii, Klebsiella pneumoniae, and Kluyvera ascorbata. Three isolates—E. bugandensis, K. pneumoniae, and K. ascorbata—were classified as multidrug-resistant (MDR). Widespread resistance to β-lactams and cephalosporins was detected, and some isolates were resistant to quinolones, nitrofurans, and phosphonic acids. The gene blaCTX-M-2 was detected in C. freundii, E. bugandensis, E. kobei, and K. ascorbata. However, genes blaNDM, blaKPC, blaCMY-1, and blaCMY-2 were not detected in any isolate. The findings underscore the need to enhance good manufacturing practices in this sector to control the spread of antimicrobial resistance (AMR). To our knowledge, this is the first study documenting the presence of potentially pathogenic enterobacteria in coconut water samples and their associated phenotypic and genotypic AMR profiles. Full article
(This article belongs to the Special Issue Antimicrobial Resistance in Enterobacteriaceae and Enterococci)
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