Advances in Microbial Synthetic Biology

Dear Colleagues,

Microbial synthetic biology is a rapidly developing field at the intersection of biology, engineering, and computer science. Using microorganisms, researchers can design and construct new biological products and systems for useful purposes. The applications of microbial synthetic biology are vast, ranging from medicine and agriculture to environmental sustainability and bioenergy.

This Special Issue aims to highlight the latest breakthroughs and innovative approaches in this field. We invite researchers to contribute original research articles, reviews, and perspectives that explore various aspects of microbial synthetic biology, including but not limited to the following:

• Genetic design and engineering: Development of novel genetic designs for precise control of gene expression and cellular behavior in microorganisms;
• Metabolic pathway engineering: Optimization and redesign of microbial metabolic pathways for the efficient production of biofuels, pharmaceuticals, and other valuable chemicals;
• Synthetic genomics: Advances in the synthesis and assembly of large DNA sequences, including synthetic genomes, to create engineered microorganisms with targeted functions;
• Microbial consortia and communities: Engineering microbial consortia to perform complex functions, including bioremediation, nutrient cycling, and industrial bioprocesses;
• Tools and technologies: Development of new tools and technologies for synthetic biology, such as CRISPR-based genome editing and high-throughput screening methods;
• Biosensors and diagnostics: Development of microbial biosensors for environmental monitoring, disease diagnosis, and harmful substance detection;
• Applications in medicine: Engineering of microorganisms for therapeutic applications, including drug delivery, microbiome modulation, and the production of biopharmaceuticals;
• Environmental and agricultural applications: Utilization of synthetic biology to address environmental challenges, such as pollution and waste management, and to enhance agricultural productivity and sustainability.

Prof. Dr. Hailong Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• microbial gene editing
• metabolic engineering
• engineered microorganisms
• microbial biosensors
• biosynthesis