Respiratory Viruses in the Age of Metagenomics
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Systems Microbiology".
Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 13934
Special Issue Editor
2. Laboratoire de Virologie, IAI, CBN, Hospices Civils de Lyon, Lyon, France
3. Centre National de Reference Virus Influenzae, IAI, CBN, Hospices Civils de Lyon, Lyon, France
Interests: bioinformatics; influenza; molecular biology; virology; influenza A virus; virome; microbiome; respiratory tract infection; metagenomics
Special Issue Information
Dear Colleagues,
Respiratory viruses cause both common acute respiratory infections and severe complications, including pneumonia and exacerbation of chronic respiratory diseases. A large number of individuals are affected each year worldwide, with substantial medical and economic impact.
In recent years, clinical metagenomic next-generation sequencing (mNGS) has been shifting paradigms in microbiology by providing access to genomes of whole microbial communities in clinical samples. Combined with other omics approaches, mNGS allows one to take a holistic perspective of respiratory virus infection and presents new prospects in the field of respiratory viruses’ surveillance and biology, including improved diagnosis and surveillance and a better understanding of pathogenesis and options for treatment.
The aim of this Special Issue is to present advances in our understanding of respiratory viruses’ epidemiology, pathogenesis, and control, in the era metagenomics.
For this purpose, we welcome the submission of research articles, review articles, and short communications using mNGS to provide novel insights into the various aspects of respiratory virus infection: the diagnosis of new or divergent viruses, technical challenges and the interpretation issues of mNGS, epidemiology, within-host evolution of respiratory viruses, virus–host interactions (pathogenesis, host responses to infection, the role of the respiratory virome, interactions with the microbiome), clinical management, therapy, and prevention.
Dr. Laurence Josset
Guest Editor
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Keywords
- Respiratory viruses;
- Metagenomics;
- Microbiome;
- Virome;
- Next-generation sequencing;
- Respiratory tract infection;
- Influenza;
- Respiratory syncytial virus;
- Epidemiology;
- Diagnosis;
- Diversity;
- Pathogenesis;
- Treatment;
- Prevention.
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