Chemical Biology of Antimicrobial Resistance, 2nd Edition
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Cross-Field Chemistry".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 458
Special Issue Editor
Interests: novel pathogen; magnetic assembly; magnetic separation; synthetic microbe; rhizosphere microbiome; antimicrobial therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The O’Neill report on antimicrobial resistance (AMR) projects that by 2050, AMR could be responsible for up to 10 million deaths annually. ESKAPE pathogens—Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species—have already led to hundreds of fatalities. These pathogens have further evolved into multidrug-resistant strains, including Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria, Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococci (VRE), for which no effective treatments currently exist. Concurrently, drug-resistant pathogenic fungi such as Candida albicans, Candida auris, and Aspergillus fumigatus are emerging as significant threats to clinical patients.
Given the urgency of this situation, there is a critical need to develop new therapeutics targeting these deadly multidrug-resistant pathogens through novel mechanisms of action. This Special Issue seeks to gather research in chemical biology aimed at addressing this global crisis, which could lead to unprecedented consequences. The scope includes the discovery of new drug-resistant genes and their underlying mechanisms, the environmental distribution and transmission of MDR genes, strategies to control the environmental spread of MDR genes and pathogens, molecular probes for studying antimicrobial resistance and antibiotic mechanisms, novel diagnostic methods, antibiotic molecules with innovative modes of action, and new antibiotic strategies and targets.
Submissions of manuscripts presenting original research in the expansive field of chemical biology are welcome. I anticipate that this Special Issue will offer valuable and distinctive insights into the pressing challenge of antimicrobial resistance.
Prof. Dr. Qilin Yu
Guest Editor
Manuscript Submission Information
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Keywords
- antimicrobial resistance
- resistance mechanism
- antibiotics
- diagnostics
- new mode of action
- antibiotic target
- structure–activity relationship
- molecular probe
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Related Special Issue
- Chemical Biology of Antimicrobial Resistance in Molecules (9 articles)
