Bioactive Compounds with Applications in Health and Food
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 69423
Special Issue Editor
2. Institute of Chemical Biology, National Hellenic Research Foundation, 116 35 Athens, Greece
Interests: molecular design; bioanalysis; metabolic profiling; design and development of dietary supplements; functional food; phytoconstituents
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bioactive compounds constitute a significant field of natural products chemistry, mainly because of their structural biodiversity and their high exploitation potential. They are chemical entities that exhibit certain biological effects, related to their ability to modulate metabolic processes, and activate or inhibit receptors or enzymes with a beneficial response in the human body. Their consumption has been related to the prevention of multiple pathologies, and to the promotion of good health. Plant bioactive compounds are produced as secondary metabolites, and have singnificant and still unexplored health benefits. Natural bioactives (i.e., carotenoids, polyphenols), either isolated or in extracts, are mainly used for the development of food supplements and cosmetics, but are also widely incorporated into food products in order to enhance their sensory, nutritional, or health properties.
Stemming from the structure of natural bioactives, there is a growing trend towards the design and synthesis of new chemical entitites under the name “bio-inspired compounds”, with their structural motifs inspired by natural bioactives compounds.
This Special Issue aims to cover the current trends and the recent progress on bioactive compounds with applications in health and food. The objective of the Issue is to constitute a source of relevant information on either isolated bioactive or synthesized bioinspired compounds, as well as bioactive extracts, which could potentially be exploited for the development of pharmaceuticals, comeceuticals, and nutraceuticals.
Focus will be given to solid research findings for compounds or extracts with activities on specific biological targets or pharmacological models. Any kind of health topic related biological targtets is accepted. Papers with the main objective being the in vitro studies of the antioxidant/radical scavenging activities of plant extracts should at least provide a chemical profile of the extract, if not a complete identification and quantifiation of the relevant bioactive compounds. To this extent, studies focusing on the use of modern analytical techniques that allow for the identification of bioactive compounds and deepening the mechanisms that relate them to health are also accepted.
Types of contributions to this Special Isssue can be original research articles, short communications, and reviews/mini-reviews.
Submissions on, but not limited to, the following are welcome:
- Isolation and characterization of bioactive compounds
- Selective extraction of bioactive compounds
- Biological evaluation of selected plant extracts/ isolated and/or synthetic compounds
- Design and synthesis of bio-inspired compounds
- Hit discovery and hit-to-lead optimization of bio-inspired compounds
- Structure–activity relationship studies
Dr. Panagiotis Zoumpoulakis
Guest Editor
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Keywords
- Bioactive compounds
- Natural products
- Extraction methodologies
- Bio-inspired compounds
- Design and synthesis
- Hit discovery
- Hit-to-lead optimization
- Analytical techniques and methodologies
- Structure–activity Relationship
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