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Biomimetic and Functional Materials for Biomedical and Dental Applications

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 371

Special Issue Editor


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Guest Editor
School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Interests: dental materials; resin bonding agents; physical properties; antibacterial properties; caries prevention; drug carrier compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Improvements and innovations in the fields of chemistry, physics and engineering have empowered us with an enhanced understanding of the composition and control of materials in terms of structure, property, and performance relationships. Consequently, significant advancements have been made in the engineering of innovative functional and biomimetic materials that take inspiration from nature. These materials are therefore expected to have an impact on many aspects of human life, including health sciences and the environment. In particular, the design and development of such materials for healthcare applications are highly demanding. Research studies on the application of biomimetic and functional materials in the fields of biomedicine and dentistry focus on the development of materials with enhanced mechanical properties and biocompatibility that mimic the characteristics of natural soft and hard tissues in the human body. However, the research and application of biomimetic materials in healthcare remain in an early stage of investigation. Therefore, this Special Issue of Molecules will serve as a platform for the analysis of recent advances in the development and utilization of biomimetic functional materials in both biomedical sciences and dentistry. I kindly invite you to submit contributions in the form of short communications, original research articles or review papers.

Prof. Dr. Fusun Ozer
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • functional materials
  • biomimetic materials
  • biomimetic
  • mechanical properties
  • biomedical
  • bioengineering
  • tissue engineering

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Published Papers (1 paper)

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Research

19 pages, 2417 KiB  
Article
Modification of 316L Stainless Steel, Nickel Titanium, and Cobalt Chromium Surfaces by Irreversible Immobilization of Fibronectin: Towards Improving the Coronary Stent Biocompatibility
by Hesam Dadafarin, Evgeny Konkov, Hojatollah Vali, Irshad Ali and Sasha Omanovic
Molecules 2024, 29(20), 4927; https://doi.org/10.3390/molecules29204927 - 18 Oct 2024
Viewed by 289
Abstract
An extracellular matrix protein, fibronectin (Fn), was covalently immobilized on 316L stainless steel, L605 cobalt chromium (CoCr), and nickel titanium (NiTi) surfaces through an 11-mercaptoundecanoic acid (MUA) self-assembled monolayer (SAM) pre-formed on these surfaces. Polarization modulation infrared reflection adsorption spectroscopy (PM-IRRAS) confirmed the [...] Read more.
An extracellular matrix protein, fibronectin (Fn), was covalently immobilized on 316L stainless steel, L605 cobalt chromium (CoCr), and nickel titanium (NiTi) surfaces through an 11-mercaptoundecanoic acid (MUA) self-assembled monolayer (SAM) pre-formed on these surfaces. Polarization modulation infrared reflection adsorption spectroscopy (PM-IRRAS) confirmed the presence of Fn on the surfaces. The Fn monolayer attached to the SAM was found to be stable under fluid shear stress. Deconvolution of the Fn amide I band indicated that the secondary structure of Fn changes significantly upon immobilization to the SAM-functionalized metal substrate. Scanning electron microscopy and energy dispersive X-ray analysis revealed that the spacing between Fn molecules on a modified commercial stent surface is approximately 66 nm, which has been reported to be the most appropriate spacing for cell/surface interactions. Full article
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