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New Processes in Copper Catalysis

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (15 October 2021) | Viewed by 2875

Special Issue Editor


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Guest Editor
Departamento de Quı́mica Orgánica, Facultad de Ciencias, Universidad de Cádiz, 11510 Puerto Real, Cádiz, Spain
Interests: organic chemistry; catalysis; C-H functionalization; heterogeneous catalyst; copper mixed oxides; design of experiments; microwave-assisted synthesis

Special Issue Information

Dear Colleagues, 

Amongst transition metal catalysts used in organic chemistry, copper is a low-cost coinage metal that is distributed worldwide and is also more environmentally friendly than other metallic catalysts. Moreover, copper-based catalysts can be involved in two-electron or single-electron processes depending on its oxidative stage. In addition, it is very prone to coordinate to heteroatoms and multiple bonds, which makes its use as a catalyst extremely wide and diverse, with a plethora of applications. Despite having been intensively used in catalysis, interest in this metal is raising due to its role in new functionalizations and in new homogeneous and heterogeneous copper-based catalysts alike. Therefore, this Special Issue aims to showcase the latest research on this topic.

Dr. F. Javier Moreno-Dorado
Guest Editor

Manuscript Submission Information

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Keywords

  • Organic synthesis
  • Homogeneous catalysis
  • Heterogeneous catalysis
  • Copper catalyst
  • C-H functionalization
  • Environmentally friendly catalyst
  • Low-cost catalyst

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Published Papers (1 paper)

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Research

9 pages, 3543 KiB  
Article
Copper-Catalyzed Dual Cyclization for the Synthesis of Quinindolines
by Hung-Kai Wang, Yu-Lun Chio, Gangaram Pallikonda, Hsyueh-Liang Wu, Haw-Lih Su and Jen-Chieh Hsieh
Molecules 2020, 25(22), 5303; https://doi.org/10.3390/molecules25225303 - 13 Nov 2020
Cited by 3 | Viewed by 2408
Abstract
A synthetic approach to quinindoline derivatives by the Cu-catalyzed dual cyclization has been developed. This catalytic reaction is a practical method for the systematic synthesis of quinindoline core structure, which contains a limited-step synthetic strategy and can tolerant a wide variety of substituents. [...] Read more.
A synthetic approach to quinindoline derivatives by the Cu-catalyzed dual cyclization has been developed. This catalytic reaction is a practical method for the systematic synthesis of quinindoline core structure, which contains a limited-step synthetic strategy and can tolerant a wide variety of substituents. In addition, the mechanistic study reveals that the reaction initiates from a Lewis acid accelerated addition of aniline to nitrile and provides the indole substructure, and then the subsequent Cu-catalyzed C-N coupling reaction furnishes the quinoline subunit and affords the quinindoline structure. Full article
(This article belongs to the Special Issue New Processes in Copper Catalysis)
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