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Advances in the Design and Synthesis of Novel Macrocyclic Host Molecules

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 2451

Special Issue Editor


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Guest Editor
Department of Chemistry & Nanoscience Centre, University of Jyväskylä, Jyväskylä, Finland
Interests: supramolecular and macrocyclic chemistry; interlocked molecules; molecular nanotopology; molecular recognition

Special Issue Information

Dear Colleagues,

Macrocycles hold a privileged place in the field of molecular recognition. Suitably designed, they can recognize ions and small molecules with great levels of selectivity, even in competing media such as water. Every day, macrocyclic hosts are finding new applications in the context of anion capture, transport, sensing, molecular machinery, etc. The structural diversity of synthetic macrocycles is constantly expanding, and the rapid development of strategies enabling access to macrocyclic species with complex topologies (e.g., multiply interlocked catenanes and knots) is likely to push the boundaries of the field in new directions in the near future. It is therefore timely to gather studies reflecting the current state-of-the-art of the host–guest chemistry of macrocycles.

The aim of this Special Issue is to highlight some of the latest developments in all areas of research related to the design and synthesis of macrocyclic hosts.

Prof. Dr. Fabien B. L. Cougnon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • macromolecules
  • host–guest complexes
  • anion recognition
  • supramolecular interactions

Published Papers (1 paper)

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Research

7 pages, 883 KiB  
Communication
Self-Assembly of a Purely Organic Bowl in Water via Acylhydrazone Formation
by Guangcheng Wu, Tianyu Jiao and Hao Li
Molecules 2023, 28(3), 976; https://doi.org/10.3390/molecules28030976 - 18 Jan 2023
Cited by 3 | Viewed by 2093
Abstract
A bowl-shaped molecule can be self-assembled by condensing a triscationic hexaaldehyde compound and three equiv. of a dihydrazide linkers in pure water. The molecular bowl is thus composed of a triscationic π-electron deficient platform, as well as a hexagonal rim that contains six [...] Read more.
A bowl-shaped molecule can be self-assembled by condensing a triscationic hexaaldehyde compound and three equiv. of a dihydrazide linkers in pure water. The molecular bowl is thus composed of a triscationic π-electron deficient platform, as well as a hexagonal rim that contains six acylhydrazone functions. When the counteranions are chloride, the solid-state structure reveals that this molecular bowl undergoes dimerization via N–H···Cl hydrogen bonds, forming a cage-like dimer with a huge inner cavity. This molecular bowl can employ its cavity to accommodate a hydrophobic guest, namely 1-adamantanecarboxylic acid in aqueous media. Full article
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