Nutritional Interventions to Enhance Skeletal Muscle Function and Metabolism in Aging
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".
Deadline for manuscript submissions: 15 April 2026 | Viewed by 44
Special Issue Editors
Interests: nutrition; exercise; body composition; muscle and fat mass; muscle metabolism; muscle biomarkers; healthy aging
Interests: exercise; nutrition; musculoskeletal health; skeletal muscle; inflammation; immunology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Skeletal muscle, the body’s most abundant tissue, is essential for movement, posture, and overall mobility. Beyond its mechanical role, healthy skeletal muscle serves as a major regulator of energy metabolism and insulin sensitivity, thereby contributing to the prevention of type 2 diabetes, obesity, and cardiovascular disease. Furthermore, skeletal muscle acts as an endocrine organ by communicating with other tissue types to reduce the risk of disease. Maintaining skeletal muscle health is therefore critical for preserving physical function, independence, and overall health across the lifespan.
With advancing age, skeletal muscle undergoes loss of mass, among other structural and functional changes. These include shifts in muscle fiber type, declines in contractile properties, and reductions in metabolic capacity. Such alterations impair physical performance and increase susceptibility to frailty, disability, and chronic disease. Understanding the mechanisms underlying these changes is essential for developing strategies to mitigate age-related decline.
Nutritional interventions offer promising approaches to preserve and enhance musculoskeletal health in aging populations. Adequate protein intake, omega-3 fatty acids, creatine, and other key nutrients have been shown to support muscle mass, strength, and metabolism. This Special Issue seeks to advance knowledge on how nutrition influences skeletal muscle function and metabolism in the context of aging. We welcome contributions that explore molecular, cellular, and physiological mechanisms, as well as translational studies in animal models and human populations
Dr. Zahra Farahnak
Dr. Stephen Cornish
Guest Editors
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Keywords
- skeletal muscle
- nutrition
- nutritional interventions
- muscle function
- muscle metabolism
- aging
- healthy aging
- muscle structure
- chronic disease
- frailty
- muscle physiology
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