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Nutrition and Brain Health Across the Lifespan: Insights into Mental, Cognitive, and Sleep Outcomes in Health and Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Neuro Sciences".

Deadline for manuscript submissions: 25 December 2025 | Viewed by 776

Special Issue Editors

Dr. Piril Hepsomali

E-Mail Website
Guest Editor
School of Psychology and Clinical Language Sciences, University of Reading, Reading RG6 6ET, UK
Interests: nutritional psychiatry; gut–brain axis; neuroscience; psychobiotics; functional foods; inflammation
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Adele Costabile

E-Mail Website
Guest Editor
School of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK
Interests: gut microbiota and microbiome; functional foods; clinical nutrition; metagenomics and microbial genomics; metabolomics; metabolic health
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

There is growing evidence that nutrition is vital role for supporting mental well-being, cognitive function, and sleep health through varied interacting biological and neural mechanisms. This Special Issue invites cutting-edge contributions from in vitro, preclinical, and human studies, including cross-sectional, longitudinal, and intervention-based designs, that explore how nutrition influences brain health across the human lifespan, from early development to older adulthood. We are particularly interested in work that investigates or elucidates underlying mechanistic pathways in both healthy individuals and clinical populations across all stages of life. We welcome a wide range of manuscript types, including original research articles, systematic, narrative and scoping reviews, meta-analyses, short communications, and commentaries and perspectives.

Dr. Piril Hepsomali
Prof. Dr. Adele Costabile
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutritional psychiatry and neuroscience
  • gut microbiome
  • oral microbiome
  • gut–brain axis
  • systemic and neuroinflammation
  • cognitive function
  • mental health
  • sleep and circadian rhythms
  • cognitive development
  • infant and child brain health
  • adolescent mental health
  • aging and cognitive decline
  • psychobiotics
  • functional foods
  • nutrition
  • diet
  • brain imaging
  • neurotransmitters
  • non-communicable diseases
  • metabolic disorders

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Published Papers (1 paper)

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Research

18 pages, 758 KB  
Article
How Important Are Dietary Habits Compared to Other Factors for Sleep Quality?—An Analysis Using Data from a Specific Region in Japan
by Makoto Hazama, Hiroyo Kagami-Katsuyama, Naohito Ito, Mari Maeda-Yamamoto and Jun Nishihira
Nutrients 2025, 17(17), 2787; https://doi.org/10.3390/nu17172787 - 27 Aug 2025
Viewed by 431
Abstract
Background/Objectives: The improvement of sleep quality is unquestionably a critical issue in public health. While numerous factors influence sleep quality, the relative importance of dietary habits remains insufficiently understood. The objective of this study is to evaluate the contribution of dietary habits [...] Read more.
Background/Objectives: The improvement of sleep quality is unquestionably a critical issue in public health. While numerous factors influence sleep quality, the relative importance of dietary habits remains insufficiently understood. The objective of this study is to evaluate the contribution of dietary habits by quantitatively comparing the effects of various determinants of sleep quality. Methods: Using sleep diary data from healthy males and females residing in a specific region of Japan, we estimated a dynamic multivariate panel model (DMPM) to obtain posterior predictive distributions on a scale that allows for comparisons across factor categories. Three outcome variables were adopted to measure sleep quality: presence or absence of daytime drowsiness, ease of falling asleep, and ease of waking up. The determinants of sleep quality examined in the analysis were categorized into six groups: stress factors, bedtime conditions, weather conditions, physical characteristics, exercise habits, and dietary habits. Results: The analysis revealed that although there were some seasonal and gender differences, dietary habits showed effect sizes that were no smaller than those of other determinants across all outcome variables. Conclusions: These results suggest that improving dietary habits, along with enhancing exercise habits and bedtime conditions, is a valid and equally important strategy for promoting better sleep. Full article
(This article belongs to the Special Issue Nutrition and Brain Health Across the Lifespan: Insights into Mental, Cognitive, and Sleep Outcomes in Health and Disease)
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